Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Pediatric Recurrent Central Nervous System Tumors”

128 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 128 results

Testing effectiveness (Phase 2)Ended earlyNCT00074334
What this trial is testing

TP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT02650401
What this trial is testing

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Who this might be right for
Solid TumorsCNS Tumors
Hoffmann-La Roche 69
Early research (Phase 1)Study completedNCT02975882
What this trial is testing

Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Childhood Solid NeoplasmRecurrent Malignant Solid NeoplasmRecurrent Primary Central Nervous System Neoplasm+2 more
Children's Oncology Group 33
Testing effectiveness (Phase 2)WithdrawnNCT00053040
What this trial is testing

Immunotoxin Therapy in Treating Children With Recurrent Malignant Gliomas

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium
Early research (Phase 1)Active Not RecruitingNCT03500991
What this trial is testing

HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

Who this might be right for
Central Nervous System Tumor, PediatricGliomaEpendymoma+6 more
Seattle Children's Hospital 10
Early research (Phase 1)Study completedNCT01158300
What this trial is testing

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 28
Early research (Phase 1)Not Yet RecruitingNCT07513194
What this trial is testing

GPC3 CAR T Cells With IL-15 and IL-21 for Recurrent ATRT and CNS Rhabdoid Tumors (RADIANT)

Who this might be right for
Atypical Teratoid Rhabdoid TumorCentral Nervous System Rhabdoid Tumor
Baylor College of Medicine 21
Testing effectiveness (Phase 2)Study completedNCT04238819
What this trial is testing

Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Who this might be right for
Relapsed Solid TumorRefractory Solid Tumor
Eli Lilly and Company 47
Not applicableStudy completedNCT01503086
What this trial is testing

Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation Therapy

Who this might be right for
Brain NeoplasmRecurrent Brain Neoplasm
Children's Oncology Group 45
Early research (Phase 1)Study completedNCT01528046
What this trial is testing

Metformin in Children With Relapsed or Refractory Solid Tumors

Who this might be right for
Solid TumorsPrimary Brain Tumors
H. Lee Moffitt Cancer Center and Research Institute 26
Testing effectiveness (Phase 2)Looking for participantsNCT05096481
What this trial is testing

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaRecurrent Medulloblastoma
Nationwide Children's Hospital 120
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Testing effectiveness (Phase 2)Study completedNCT03220035
What this trial is testing

Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+20 more
National Cancer Institute (NCI) 4
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07567469
What this trial is testing

A Safety and Efficacy Study of Combined Fianlimab + Cemiplimab in Children and Young Adults With Recurrent or Progressive High-Grade Glioma or Posterior Fossa-A Ependymoma

Who this might be right for
High-Grade Glioma (HGG)Posterior Fossa-A Ependymoma
Regeneron Pharmaceuticals 120
Early research (Phase 1)Study completedNCT00005796
What this trial is testing

Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors

Who this might be right for
Bone Marrow SuppressionBrain and Central Nervous System TumorsDrug/Agent Toxicity by Tissue/Organ
Indiana University 10
Testing effectiveness (Phase 2)Study completedNCT00179907
What this trial is testing

A Phase I/II Study of the Photon Radiosurgery System

Who this might be right for
Brain Tumor, RecurrentGlioblastoma Multiforme
Ann & Robert H Lurie Children's Hospital of Chicago 35
Early research (Phase 1)Study completedNCT01132911
What this trial is testing

A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas

Who this might be right for
LymphomaSarcomaWilmsTumor+1 more
National Cancer Institute (NCI) 5
Early research (Phase 1)Ended earlyNCT01204450
What this trial is testing

Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcoma

Who this might be right for
Brain and Central Nervous System TumorsNeuroblastomaSarcoma+1 more
UNC Lineberger Comprehensive Cancer Center 7
Testing effectiveness (Phase 2)Study completedNCT03213678
What this trial is testing

Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+30 more
National Cancer Institute (NCI) 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT02932280
What this trial is testing

Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment

Who this might be right for
Solid TumorCentral Nervous System TumorLymphoma+1 more
Memorial Sloan Kettering Cancer Center 14
Next Page