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Results for “Ph-negative Adult Acute Lymphoblastic Leukemia”

112 trials

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Showing 20 of 112 results

Very early researchStudy completedNCT01184885
What this trial is testing

A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy

Who this might be right for
Lymphoid Malignancies (New or Relapsed)Acute Lymphoblastic LeukemiaBurkitt Lymphoma+3 more
Sidney Kimmel Cancer Center at Thomas Jefferson University 7
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06773936
What this trial is testing

Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

Who this might be right for
Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaCD19+ Acute Leukemia
SWOG Cancer Research Network 55
Not applicableUnknownNCT01193933
What this trial is testing

Multicenter Clinical Trial for Adult Ph-negative ALL. Non-intensive But Non-iterruptive Treatment

Who this might be right for
Ph-negative Adult Acute Lymphoblastic Leukemia
National Research Center for Hematology, Russia 321
Not applicableLooking for participantsNCT06481228
What this trial is testing

Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL

Who this might be right for
Philadelphia Positive Acute Lymphoblastic LeukemiaAcute Lymphoblastic Leukemia, Adult
Institute of Hematology & Blood Diseases Hospital, China 82
Large-scale testing (Phase 3)UnknownNCT02611492
What this trial is testing

A Phase III Randomized Trial of the Reduction of Chemotherapy in Philadelphia Chromosome-positive ALL of Young Adults

Who this might be right for
Philadelphia Chromosome Positive Adult Acute Lymphoblastic Leukemia
Assistance Publique - Hôpitaux de Paris 265
Testing effectiveness (Phase 2)Looking for participantsNCT06918431
What this trial is testing

Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Who this might be right for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeLymphoblastic Lymphoma
City of Hope Medical Center 53
Early research (Phase 1)Looking for participantsNCT05157971
What this trial is testing

Venetoclax and a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed B Cell Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic LeukemiaPh-Like Acute Lymphoblastic Leukemia
City of Hope Medical Center 24
Testing effectiveness (Phase 2)UnknownNCT04740203
What this trial is testing

Sequential CD19 and CD22 CAR-T Therapy for Newly Diagnosed Ph- B-ALL

Who this might be right for
B-Cell Acute Lymphoblastic Leukemia, Adult
Zhejiang University 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT05456698
What this trial is testing

Efficacy and Safety of Inotuzumab Ozogamicin in Treating Adult Patients With Ph Negative ALL With Minimal Residual Disease Positive After Induction Chemotherapy

Who this might be right for
Acute Lymphocytic Leukemia
Institute of Hematology & Blood Diseases Hospital, China 31
Testing effectiveness (Phase 2)Looking for participantsNCT06220487
What this trial is testing

A Single-arm, Open-label Study of Olverembatinib, CD3/CD19 Bispecific T-cell Engager, and Chidamide in Patients With Newly Diagnosed Ph+ALL

Who this might be right for
Acute Lymphoblastic LeukemiaPhiladelphia ChromosomePhiladelphia-Positive ALL+2 more
Nanfang Hospital, Southern Medical University 67
Early research (Phase 1)Study completedNCT00351975
What this trial is testing

Belinostat and Azacitidine in Treating Patients With Advanced Hematologic Cancers or Other Diseases

Who this might be right for
Accelerated Phase of DiseaseAdult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11+17 more
National Cancer Institute (NCI) 56
Testing effectiveness (Phase 2)Ended earlyNCT03523429
What this trial is testing

PETHEMA-BLIN-01/PET069014 (BLIN-01)

Who this might be right for
Philadelphia Chromosome-negative or BCR-ABL-negative, CD19-positive ALL
PETHEMA Foundation 11
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05931757
What this trial is testing

Olverembatinib Combined With Blinatumomab in the Treatment of Ph+ ALL

Who this might be right for
Philadelphia-Positive ALL
The First Affiliated Hospital of Soochow University 22
Testing effectiveness (Phase 2)Ended earlyNCT01028716
What this trial is testing

Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Acute Biphenotypic LeukemiaAcute Erythroid Leukemia in RemissionAcute Leukemia in Remission+27 more
Fred Hutchinson Cancer Center 46
Testing effectiveness (Phase 2)Looking for participantsNCT06738368
What this trial is testing

Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeT Acute Lymphoblastic Leukemia
University of Washington 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06658925
What this trial is testing

Olverembatinib as Maintenance Therapy or Preemptive Therapy After Allo-HSCT in Ph+ALL

Who this might be right for
Ph+ Acute Lymphoblastic Leukemia (Ph+ALL)HSCTTyrosine Kinase Inhibitor
Institute of Hematology & Blood Diseases Hospital, China 50
Not applicableUnknownNCT05024357
What this trial is testing

TKI Maintenance Therapy Following Allo-HSCT in Newly Diagnosed Ph+ Adult ALL

Who this might be right for
Precursor Cell Lymphoblastic Leukemia-LymphomaPhiladelphia-Positive Acute Lymphoblastic LeukemiaALL, Adult
First Affiliated Hospital Xi'an Jiaotong University 80
Not applicableNot Yet RecruitingNCT07356960
What this trial is testing

Evaluation of the Efficacy of Ponatinib in Ph+ ALL in the Real-world

Who this might be right for
Acute Lymphobkastic LeukemiaPhiladelphia Chromosome Positive Acute Lymphoblastic Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 103
Testing effectiveness (Phase 2)Study completedNCT04554485
What this trial is testing

Blinatumomab Followed by High-dose Chemotherapy for Ph-negative Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Lymphoblastic Leukemia, Acute, AdultPh Negative ALLNewly Diagnosed
Institute of Hematology and Blood Transfusion, Czech Republic 27
Not applicableLooking for participantsNCT06785324
What this trial is testing

Study of Nutrition and Exercise in Adults Hospitalized for Treatment of Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Philadelphia Chromosome NegativeB Cell Acute Lymphoblastic Leukemia (B-ALL)B-ALL
University of Chicago 20
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