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Results for “Pharmacodynamic”

7,471 trials

Showing 20 of 7,471 results

Early research (Phase 1)Study completedNCT02104765
What this trial is testing

LY2951742 in Healthy Japanese and Caucasian Participants

Who this might be right for
Migraine Disorders
Eli Lilly and Company 45
Early research (Phase 1)Looking for participantsNCT06809400
What this trial is testing

LY4006896 in Healthy Participants and Participants With Parkinson's Disease

Who this might be right for
Parkinson Disease
Eli Lilly and Company 127
Early research (Phase 1)Study completedNCT02316756
What this trial is testing

A Single Ascending Dose Study To Evaluate Safety And Pharmacokinetics Of Compound PF-06648671 In Healthy Subjects

Who this might be right for
Healthy Subjects
Pfizer 18
Testing effectiveness (Phase 2)Study completedNCT00797745
What this trial is testing

A Pharmacokinetics/Pharmacodynamics Study of SCH 900518 in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis C (Protocol No. P05104AM2)(COMPLETED)

Who this might be right for
Hepatitis C, Chronic
Merck Sharp & Dohme LLC 111
Early research (Phase 1)Study completedNCT02348372
What this trial is testing

Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of GSK1278863A in Healthy Subjects

Who this might be right for
Anaemia
GlaxoSmithKline 34
Early research (Phase 1)Study completedNCT02340572
What this trial is testing

First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRS-080

Who this might be right for
Healthy
Pieris Pharmaceuticals GmbH 48
Testing effectiveness (Phase 2)Study completedNCT02246595
What this trial is testing

Studying Complement Inhibition in Early, Newly Developing Septic Organ Dysfunction

Who this might be right for
Severe SepsisSeptic Shock
InflaRx GmbH 72
Early research (Phase 1)Study completedNCT01814839
What this trial is testing

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

Who this might be right for
TTR-mediated Amyloidosis
Alnylam Pharmaceuticals 85
Early research (Phase 1)Ended earlyNCT03816839
What this trial is testing

Evaluation of Orally Administered Amcenestrant (SAR439859) in Japanese Postmenopausal Patients With Advanced Breast Cancer (AMEERA-2)

Who this might be right for
Breast Cancer
Sanofi 10
Early research (Phase 1)Study completedNCT01263119
What this trial is testing

LY2216684 and Warfarin in Healthy Subjects

Who this might be right for
Major Depressive Disorder
Eli Lilly and Company 18
Early research (Phase 1)Study completedNCT02418819
What this trial is testing

Examine Safety, Pharmacokinetics, And Pharmacodynamic Of Pf 06412562 In Subjects With Schizophrenia

Who this might be right for
Schizophrenia
Pfizer 103
Testing effectiveness (Phase 2)Study completedNCT00729872
What this trial is testing

A Phase 2a Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of AG011 in Ulcerative Colitis

Who this might be right for
Moderately Active Ulcerative Colitis
ActoGeniX N.V. 60
Testing effectiveness (Phase 2)Study completedNCT04826172
What this trial is testing

Exploratory Study on the Safety, Tolerability, and Pharmacodynamics of IMB-1018972 in Subjects With Angina Due to Obstructive Coronary Artery Disease (IMPROVE-Ischemia)

Who this might be right for
IschemiaCoronary Artery Disease
Imbria Pharmaceuticals, Inc. 58
Testing effectiveness (Phase 2)Ended earlyNCT02607228
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 (Alobresib) as a Single Agent and In Combination With Enzalutamide in Participants With Metastatic Castrate-Resistant Prostate Cancer

Who this might be right for
Metastatic Castrate-Resistant Prostate Cancer
Gilead Sciences 31
Early research (Phase 1)Study completedNCT03192345
What this trial is testing

A First-in-human Study of the Safety, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of SAR439459 Monotherapy and Combination of SAR439459 and Cemiplimab in Patients With Advanced Solid Tumors

Who this might be right for
Malignant Solid Tumor
Sanofi 161
Early research (Phase 1)Study completedNCT03061981
What this trial is testing

Evaluate The Safety,Tolerability, PK and PD Of DA-1241 In Healthy Male Subjects

Who this might be right for
Diabetes Mellitus, Type 2
Dong-A ST Co., Ltd. 60
Early research (Phase 1)Ended earlyNCT01514981
What this trial is testing

AMG 761 in Adults With Asthma

Who this might be right for
Asthma
Amgen 7
Early research (Phase 1)Ended earlyNCT00651365
What this trial is testing

A Safety and Dose-finding Study of JNJ-38877605 in Patients With Advanced or Refractory Solid Tumors.

Who this might be right for
Neoplasms
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 14
Early research (Phase 1)Study completedNCT01510951
What this trial is testing

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of AMG 811 in Subjects With Psoriasis

Who this might be right for
Psoriasis
Amgen 9
Early research (Phase 1)Study completedNCT02616445
What this trial is testing

Phase I MAD, Fed-Fasted, CSF Study of UE2343 in Healthy Subjects

Who this might be right for
Healthy Volunteers
Actinogen Medical 40
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