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Results for “Pharmacokinetics of MDV3100”

24 trials

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Showing 20 of 24 results

Early research (Phase 1)Study completedNCT02740985
What this trial is testing

Clinical Study of AZD4635 in Patients With Advanced Solid Malignancies

Who this might be right for
Advanced Solid MalignanciesNon-Small Cell Lung Cancer (NSCLC)Metastatic Castrate-Resistant Prostate Carcinoma (mCRPC)+1 more
AstraZeneca 313
Testing effectiveness (Phase 2)Ended earlyNCT02607228
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 (Alobresib) as a Single Agent and In Combination With Enzalutamide in Participants With Metastatic Castrate-Resistant Prostate Cancer

Who this might be right for
Metastatic Castrate-Resistant Prostate Cancer
Gilead Sciences 31
Early research (Phase 1)Study completedNCT02138162
What this trial is testing

Investigate the Effect of Severely Diminished Liver Function on the Metabolism, Safety, and Tolerability of a Single Oral Dose of Enzalutamide in Men

Who this might be right for
Severe Hepatic ImpairmentNormal Hepatic Function
Astellas Pharma Europe B.V. 16
Testing effectiveness (Phase 2)Study completedNCT02711956
What this trial is testing

ZEN003694 in Combination With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer

Who this might be right for
Metastatic Castration-Resistant Prostate Cancer
Zenith Epigenetics 75
Testing effectiveness (Phase 2)Active Not RecruitingNCT04557449
What this trial is testing

Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors

Who this might be right for
LiposarcomaProstate CancerBreast Neoplasms+1 more
Pfizer 362
Early research (Phase 1)Study completedNCT01901133
What this trial is testing

Hepatic Impairment Study With MDV3100 in Subjects With Mild and Moderate Hepatic Impairment Compared to a Healthy Control Group

Who this might be right for
Pharmacokinetics of MDV3100Healthy SubjectsKidney Diseases
Astellas Pharma Europe B.V. 33
Early research (Phase 1)Looking for participantsNCT07277270
What this trial is testing

GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors

Who this might be right for
Neoplasms
GlaxoSmithKline 84
Early research (Phase 1)Not Yet RecruitingNCT07783282
What this trial is testing

Learn How Enzalutamide, Apalutamide and Bicalutamide Affect the Way Fezolinetant is Processed in Men With Prostate Cancer

Who this might be right for
Prostate Cancer
Astellas Pharma Global Development, Inc. 56
Early research (Phase 1)Study completedNCT01913379
What this trial is testing

Drug-drug Interaction Study With MDV3100 (ASP9785) and Gemfibrozil and Itraconazole

Who this might be right for
Healthy SubjectsPharmacokineticsDrug-Drug Interaction
Astellas Pharma Europe B.V. 41
Early research (Phase 1)Study completedNCT01911715
What this trial is testing

Explore the Routes of Elimination of MDV3100

Who this might be right for
Healthy SubjectsPharmacokinetics of MDV3100
Astellas Pharma Europe B.V. 6
Early research (Phase 1)Study completedNCT04094519
What this trial is testing

Evaluate the Effect of Multiple Doses of Enzalutamide on the Pharmacokinetics of Substrates of P-glycoprotein (Digoxin) and Breast Cancer Resistant Protein (Rosuvastatin) in Male Subjects With Prostate Cancer

Who this might be right for
Prostate Cancer
Astellas Pharma Global Development, Inc. 24
Early research (Phase 1)Study completedNCT02225093
What this trial is testing

Evaluate How Daily Dosing With Enzalutamide Affects the Metabolism of Caffeine and Dextromethorphan in Men With Prostate Cancer

Who this might be right for
Pharmacokinetics of DextromethorphanPharmacokinetics of CaffeineProstate Cancer
Astellas Pharma Europe B.V. 12
Large-scale testing (Phase 3)Looking for participantsNCT06629779
What this trial is testing

Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

Who this might be right for
Metastatic Castration-Resistant Prostate Cancer
Pfizer 900
Testing effectiveness (Phase 2)Ended earlyNCT03437941
What this trial is testing

Study to Evaluate Exicorilant (CORT125281) in Combination With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer

Who this might be right for
Metastatic Castration-Resistant Prostate Cancer
Corcept Therapeutics 39
Early research (Phase 1)Study completedNCT01597193
What this trial is testing

Safety Study of Enzalutamide (MDV3100) in Patients With Incurable Breast Cancer

Who this might be right for
Breast Cancer
Pfizer 101
Early research (Phase 1)Study completedNCT02138799
What this trial is testing

Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Who this might be right for
Drug-Drug Interaction (DDI)Healthy SubjectsPharmacokinetics of Enzalutamide
Astellas Pharma Europe B.V. 28
Early research (Phase 1)Study completedNCT03569280
What this trial is testing

Evaluation of Safety and Efficacy of KPG-121 Plus Enzalutamide, Abiraterone or Apalutamide in CRPC Patients

Who this might be right for
Castration-Resistant Prostate Cancer
Kangpu Biopharmaceuticals, Ltd. 16
Early research (Phase 1)Ended earlyNCT03150056
What this trial is testing

Dose Escalation and Dose Expansion Study of GSK525762 in Combination With Androgen Deprivation Therapy in Participants With Castrate-resistant Prostate Cancer

Who this might be right for
Solid Tumours
GlaxoSmithKline 73
Early research (Phase 1)Study completedNCT01911728
What this trial is testing

Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates

Who this might be right for
Pharmacokinetics of MDV3100Castration Resistant Prostate Cancer (CRPC)
Astellas Pharma Europe B.V. 14
Early research (Phase 1)Study completedNCT02991911
What this trial is testing

A Phase 1/1b Study of MEDI3726 in Adults Subjects With Metastatic Castration Resistant Prostate Cancer

Who this might be right for
Metastatic Castration Resistant Prostate Cancer
MedImmune LLC 33
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