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Results for “Pharmacokinetics of YM178”

32 trials

Showing 20 of 32 results

Early research (Phase 1)Study completedNCT01476800
What this trial is testing

Assess Pharmacokinetic Interaction of Multiple Dose Ketoconazole on Single Dose YM178 Oral Controlled Absorption System (OCAS) in Healthy Adult Volunteers

Who this might be right for
Healthy SubjectsPharmacokinetics of YM178
Astellas Pharma Inc 24
Early research (Phase 1)Study completedNCT00856570
What this trial is testing

A Clinical Study to Determine the Effect of YM178 on the Pharmacokinetics of Warfarin in Healthy Subjects

Who this might be right for
Overactive BladderPharmacokinetics
Astellas Pharma Inc 24
Early research (Phase 1)Study completedNCT01646294
What this trial is testing

Compare the Actions in the Body of Healthy Subjects of Three Modified Release Formulations of YM178 Under Fasted and Fed Conditions With One Immediate Release Formulation of YM178 Under Fasted Conditions

Who this might be right for
Pharmacokinetics of YM178Healthy Subjects
Astellas Pharma Europe B.V. 34
Early research (Phase 1)Study completedNCT01478490
What this trial is testing

To Compare Blood and Urine Concentrations of Mirabegron (YM178) in Healthy Poor or Extensive Metabolizers for CYP2D6 and to Assess the Effect of Mirabegron on the Metabolism of Metoprolol

Who this might be right for
Pharmacokinetics of MirabegronHealthy Subjects
Astellas Pharma Inc 28
Early research (Phase 1)Study completedNCT00940121
What this trial is testing

Pharmacokinetics of Oral Mirabegron With Different Release Rates Versus Intravenous (IV) Mirabegron

Who this might be right for
HealthyPharmacokinetics of Mirabegron
Astellas Pharma Inc 91
Early research (Phase 1)Study completedNCT02127034
What this trial is testing

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Who this might be right for
Healthy SubjectsPharmacokineticsDrug-Drug Interaction (DDI)
Astellas Pharma Europe B.V. 26
Early research (Phase 1)Study completedNCT00965926
What this trial is testing

Investigate the Food Effect on the Pharmacokinetics of YM178 in Healthy, Non-elderly Volunteers

Who this might be right for
Healthy VolunteerPharmacokinetics of YM178
Astellas Pharma Inc 72
Early research (Phase 1)Study completedNCT01284868
What this trial is testing

A Study in Healthy Young Men to Look at What Drives the Cardiovascular Effects After Dosing With Mirabegron.

Who this might be right for
Healthy VolunteersPharmacodynamics of Mirabegron
Astellas Pharma Inc 12
Early research (Phase 1)Study completedNCT01478503
What this trial is testing

To Evaluate the Blood and Urine Concentration and the Safety and Tolerability of Increasing Repeated Doses of Mirabegron (YM178) OCAS in Healthy Young and Elderly Males and Healthy Young and Elderly Females

Who this might be right for
PharmacokineticsHealthy Subjects
Astellas Pharma Inc 96
Early research (Phase 1)Study completedNCT01651312
What this trial is testing

Assess the Systemic Pharmacokinetics, Metabolism and Excretion Routes of YM178 in Man, After Administration of Radio-labeled YM178

Who this might be right for
Metabolic Processes
Astellas Pharma Europe B.V. 4
Early research (Phase 1)Study completedNCT00939757
What this trial is testing

Study of the Effect of Food on the Pharmacokinetics of Mirabegron

Who this might be right for
HealthyPharmacokinetics of Mirabegron
Astellas Pharma Inc 76
Early research (Phase 1)Study completedNCT01478529
What this trial is testing

Find Out How Much Mirabegron Gets Into the Body After Dosing With a Tablet Formulation

Who this might be right for
Pharmacokinetics of MirabegronBioavailabilityHealthy Subjects
Astellas Pharma Inc 12
Early research (Phase 1)Study completedNCT00750620
What this trial is testing

A Pharmacokinetic Study of YM178 in Normal Subjects and Those With Mild, Moderate, and Severe Renal Impairment

Who this might be right for
Renal Impairment
Astellas Pharma Inc 33
Early research (Phase 1)Study completedNCT01297179
What this trial is testing

Evaluate the Possible Effects of Taking Mirabegron While Taking a Contraceptive Pill

Who this might be right for
Healthy VolunteersPharmacokinetics of Mirabegron
Astellas Pharma Inc 30
Early research (Phase 1)Study completedNCT01334905
What this trial is testing

Investigate the Safety and Effect of Food on the Pharmacokinetics of YM178 in Healthy Volunteers

Who this might be right for
Healthy VolunteerPharmacokinetics of YM178
Astellas Pharma Inc 12
Large-scale testing (Phase 3)Active Not RecruitingNCT05621616
What this trial is testing

Learn How Effective and Safe the Drug 'Mirabegron' is and How Long it Stays in the Body of Children Aged 6 Months to Less Than 3 Years of Age With Neurogenic Detrusor Overactivity

Who this might be right for
Neurogenic Detrusor Overactivity
Astellas Pharma Global Development, Inc. 7
Early research (Phase 1)Study completedNCT01478568
What this trial is testing

To Evaluate the Effect of Mirabegron (YM178) on Blood Levels of Desipramine When They Are Taken Together

Who this might be right for
Pharmacokinetics of MirabegronHealthy Subjects
Astellas Pharma Inc 28
Early research (Phase 1)Study completedNCT01663961
What this trial is testing

Evaluate the Effect of a Single Dose of Digoxin on the Actions in the Bodies of Healthy Subjects After Having Taken Several Doses of YM178

Who this might be right for
Healthy
Astellas Pharma Europe B.V. 25
Post-approval studies (Phase 4)Study completedNCT04501640
What this trial is testing

Investigate the Effect of Food With Mirabegron in Healthy Chinese Participants

Who this might be right for
Pharmacokinetics of MirabegronFood EffectHealthy Chinese Subjects
Astellas Pharma China, Inc. 24
Large-scale testing (Phase 3)Study completedNCT02751931
What this trial is testing

Open-label Phase 3 Study With Mirabegron in Children From 3 to Less Than 18 Years of Age With Neurogenic Detrusor Overactivity

Who this might be right for
Neurogenic Detrusor Overactivity
Astellas Pharma Europe B.V. 91
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