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Results for “Pharmacokinetics of YM178”

32 trials

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Showing 20 of 32 results

Early research (Phase 1)Study completedNCT02127034
What this trial is testing

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Who this might be right for
Healthy SubjectsPharmacokineticsDrug-Drug Interaction (DDI)
Astellas Pharma Europe B.V. 26
Post-approval studies (Phase 4)Study completedNCT04501640
What this trial is testing

Investigate the Effect of Food With Mirabegron in Healthy Chinese Participants

Who this might be right for
Pharmacokinetics of MirabegronFood EffectHealthy Chinese Subjects
Astellas Pharma China, Inc. 24
Early research (Phase 1)Study completedNCT00965926
What this trial is testing

Investigate the Food Effect on the Pharmacokinetics of YM178 in Healthy, Non-elderly Volunteers

Who this might be right for
Healthy VolunteerPharmacokinetics of YM178
Astellas Pharma Inc 72
Early research (Phase 1)Study completedNCT01579461
What this trial is testing

Investigate the Effect of Mirabegron (YM178) on Subjects With Mild or Moderate Hepatic Impairment Compared to Healthy Subjects

Who this might be right for
PharmacokineticsHealthy SubjectsMild and Moderate Hepatic Impairment
Astellas Pharma Europe B.V. 32
Early research (Phase 1)Study completedNCT02526979
What this trial is testing

Evaluate the Pharmacokinetics, Safety and Tolerability of Mirabegron Oral Suspension in Pediatric Subjects From 3 to Less Than 12 Years of Age With Neurogenic Detrusor Overactivity (NDO) or Overactive Bladder (OAB)

Who this might be right for
Overactive BladderNeurogenic Detrusor Overactivity
Astellas Pharma Europe B.V. 9
Large-scale testing (Phase 3)Active Not RecruitingNCT05621616
What this trial is testing

Learn How Effective and Safe the Drug 'Mirabegron' is and How Long it Stays in the Body of Children Aged 6 Months to Less Than 3 Years of Age With Neurogenic Detrusor Overactivity

Who this might be right for
Neurogenic Detrusor Overactivity
Astellas Pharma Global Development, Inc. 7
Early research (Phase 1)Study completedNCT00939757
What this trial is testing

Study of the Effect of Food on the Pharmacokinetics of Mirabegron

Who this might be right for
HealthyPharmacokinetics of Mirabegron
Astellas Pharma Inc 76
Large-scale testing (Phase 3)Ended earlyNCT04641975
What this trial is testing

Evaluate Mirabegron in Pediatric Participants From 5 to Less Than 18 Years of Age With Overactive Bladder (OAB)

Who this might be right for
Overactive Bladder (OAB)Pharmacokinetics of Mirabegron
Astellas Pharma Global Development, Inc. 26
Large-scale testing (Phase 3)Study completedNCT02751931
What this trial is testing

Open-label Phase 3 Study With Mirabegron in Children From 3 to Less Than 18 Years of Age With Neurogenic Detrusor Overactivity

Who this might be right for
Neurogenic Detrusor Overactivity
Astellas Pharma Europe B.V. 91
Early research (Phase 1)Study completedNCT01720212
What this trial is testing

Study to Assess the Safety and Plasma Concentration of YM178 OCAS Tablet (Mirabegron) in Healthy Chinese Volunteers

Who this might be right for
Healthy Chinese Volunteers
Astellas Pharma China, Inc. 24
Early research (Phase 1)Study completedNCT01285596
What this trial is testing

Evaluate How Mirabegron Enters and Leaves the Bloodstream According to Age and Sex

Who this might be right for
Healthy VolunteersPharmacokinetics of Mirabegron
Astellas Pharma Inc 75
Early research (Phase 1)Study completedNCT00940121
What this trial is testing

Pharmacokinetics of Oral Mirabegron With Different Release Rates Versus Intravenous (IV) Mirabegron

Who this might be right for
HealthyPharmacokinetics of Mirabegron
Astellas Pharma Inc 91
Early research (Phase 1)Study completedNCT01478529
What this trial is testing

Find Out How Much Mirabegron Gets Into the Body After Dosing With a Tablet Formulation

Who this might be right for
Pharmacokinetics of MirabegronBioavailabilityHealthy Subjects
Astellas Pharma Inc 12
Early research (Phase 1)Study completedNCT02211846
What this trial is testing

Evaluate the Pharmacokinetics, Safety and Tolerability of Mirabegron OCAS (Oral Controlled Absorption System) in Pediatric Subjects With Neurogenic Detrusor Overactivity or Overactive Bladder

Who this might be right for
Neurogenic Detrusor OveractivityOveractive BladderPharmacokinetics of Mirabegron
Astellas Pharma Inc 34
Early research (Phase 1)Study completedNCT00856570
What this trial is testing

A Clinical Study to Determine the Effect of YM178 on the Pharmacokinetics of Warfarin in Healthy Subjects

Who this might be right for
Overactive BladderPharmacokinetics
Astellas Pharma Inc 24
Early research (Phase 1)Study completedNCT01478490
What this trial is testing

To Compare Blood and Urine Concentrations of Mirabegron (YM178) in Healthy Poor or Extensive Metabolizers for CYP2D6 and to Assess the Effect of Mirabegron on the Metabolism of Metoprolol

Who this might be right for
Pharmacokinetics of MirabegronHealthy Subjects
Astellas Pharma Inc 28
Early research (Phase 1)Study completedNCT01284868
What this trial is testing

A Study in Healthy Young Men to Look at What Drives the Cardiovascular Effects After Dosing With Mirabegron.

Who this might be right for
Healthy VolunteersPharmacodynamics of Mirabegron
Astellas Pharma Inc 12
Early research (Phase 1)Study completedNCT01747564
What this trial is testing

Evaluate Absorption, Distribution and Elimination of Mirabegron After Oral Administration to Non-elderly Healthy Chinese Subjects

Who this might be right for
Healthy SubjectsPlasma Concentration of Mirabegron
Astellas Pharma Inc 24
Early research (Phase 1)Study completedNCT01476800
What this trial is testing

Assess Pharmacokinetic Interaction of Multiple Dose Ketoconazole on Single Dose YM178 Oral Controlled Absorption System (OCAS) in Healthy Adult Volunteers

Who this might be right for
Healthy SubjectsPharmacokinetics of YM178
Astellas Pharma Inc 24
Early research (Phase 1)Study completedNCT01651312
What this trial is testing

Assess the Systemic Pharmacokinetics, Metabolism and Excretion Routes of YM178 in Man, After Administration of Radio-labeled YM178

Who this might be right for
Metabolic Processes
Astellas Pharma Europe B.V. 4
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