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Results for “Pharmacological Action”

291 trials

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Showing 20 of 291 results

Testing effectiveness (Phase 2)Study completedNCT00702585
What this trial is testing

Study to Investigate the Optimal Dose of Org 36286 to Induce Monofollicular Ovulation in Women With WHO Group II Anovulatory Infertility (P07016)

Who this might be right for
Infertility
Organon and Co 55
Not applicableEnded earlyNCT02455024
What this trial is testing

An Observational Registry to Evaluate the Incidence of and Risk Factors for Vascular Occlusive Events Associated With ICLUSIG®

Who this might be right for
Myeloid Leukemia, Chronic-Phase, Accelerated-Phase, Blast-Phase, Ph+ALL
Ariad Pharmaceuticals 3
Testing effectiveness (Phase 2)Ended earlyNCT01555489
What this trial is testing

Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca

Who this might be right for
Stage IV Pancreatic Cancer
Thomas Jefferson University 11
Early research (Phase 1)Study completedNCT01284868
What this trial is testing

A Study in Healthy Young Men to Look at What Drives the Cardiovascular Effects After Dosing With Mirabegron.

Who this might be right for
Healthy VolunteersPharmacodynamics of Mirabegron
Astellas Pharma Inc 12
Large-scale testing (Phase 3)Active Not RecruitingNCT04784715
What this trial is testing

Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)

Who this might be right for
Breast Cancer; HER2-positive; Metastatic
AstraZeneca 1,157
Testing effectiveness (Phase 2)Active Not RecruitingNCT04699188
What this trial is testing

Study of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation

Who this might be right for
KRAS G12C Mutant Solid TumorsCarcinoma, Non-Small-Cell LungCarcinoma, Colorectal+7 more
Novartis Pharmaceuticals 344
Testing effectiveness (Phase 2)Study completedNCT02220803
What this trial is testing

A Short Term Open, Randomized Cross-over Trial Exploring the Effect of Carbonic Anhydrase Inhibition by Acetazolamide on Sleep Apnea Associated Hypertension and Vascular Dysfunction

Who this might be right for
Obstructive Sleep ApneaSleep-Disordered BreathingBlood Pressure+1 more
Göteborg University 13
Not applicableStudy completedNCT04190537
What this trial is testing

PARADOX - the Incidence of Paradoxical Reactions in Pediatric Patients Premedicated with Midazolam

Who this might be right for
Pharmacological Action
Masaryk Hospital Usti nad Labem 749
Large-scale testing (Phase 3)Looking for participantsNCT07555483
What this trial is testing

A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha 1 Antitrypsin Deficiency
Grifols Therapeutics LLC 40
Post-approval studies (Phase 4)Study completedNCT02272296
What this trial is testing

Reliability of Insulin by Jet Injection

Who this might be right for
Diabetes Mellitus
Radboud University Medical Center 30
Large-scale testing (Phase 3)Study completedNCT01701401
What this trial is testing

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination (FDC) With and Without Ribavirin for the Treatment of HCV

Who this might be right for
Chronic Hepatitis C Virus
Gilead Sciences 870
Testing effectiveness (Phase 2)Study completedNCT01681095
What this trial is testing

Custodiol-HTK (Histidine-tryptophan-ketoglutarate) Solution as a Cardioplegic Agent

Who this might be right for
Coronary Artery DiseaseMyocardial IschemiaCoronary Disease+2 more
Marc Sakwa, MD 110
Early research (Phase 1)Study completedNCT02010970
What this trial is testing

A Phase I Study in Healthy Volunteers to Assess the Effect of Cytochrome3A4 (CYP3A4) Inhibitors (Diltiazem and Itraconazole) on the Pharmacokinetics (PK) of AZD3293 and the Effects of AZD3293 on the Pharmacokinetics of Midazolam, a Cytochrome 3A4 and Cytochrome 3A5 (CYP3A4/CYP3A5) Substrate

Who this might be right for
Healthy VolunteersPharmacologic Action
AstraZeneca 56
Post-approval studies (Phase 4)Study completedNCT01201811
What this trial is testing

Study of Azacitidine in Adult Taiwanese Subjects With Higher-Risk Myelodysplastic Syndromes (MDS)

Who this might be right for
Myelodysplastic Syndromes
Celgene 44
Not applicableStudy completedNCT02152553
What this trial is testing

Biomarker(s) for Glucocorticoids

Who this might be right for
Addison Disease
Vastra Gotaland Region 11
Large-scale testing (Phase 3)Study completedNCT01444651
What this trial is testing

A Trial of Tadalafil and Glycemic Traits

Who this might be right for
Cardiovascular DiseaseInsulin ResistanceGlucose Intolerance+1 more
Thomas J. Wang, MD 73
Early research (Phase 1)UnknownNCT01611961
What this trial is testing

Docetaxel Lipid Microsphere (DT-LM) for Injection in Chemotherapy Patients

Who this might be right for
Advanced Cancer
Shenyang Pharmaceutical University 35
Testing effectiveness (Phase 2)Study completedNCT01047436
What this trial is testing

Efficacy of ArTiMist™ in Children

Who this might be right for
Falciparum Malaria
Proto Pharma Ltd 31
Early research (Phase 1)UnknownNCT01239888
What this trial is testing

Oxytocin and Tibolone Adjuncts in Treatment Resistant Depression - A Pilot Study

Who this might be right for
DepressionMajor Depressive Disorder
The Alfred 15
Post-approval studies (Phase 4)Study completedNCT01014624
What this trial is testing

Prasugrel/Clopidogrel Maintenance Dose Washout Study

Who this might be right for
Coronary Artery Disease
Daiichi Sankyo 56
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