Not applicableStudy completedNCT03740386What this trial is testingPhentolamine Mesylate as a Reversal of Local AnesthesicsWho this might be right forAnesthesia, Local León Formación 90
Post-approval studies (Phase 4)Study completedNCT00104104What this trial is testingA Multiple Myeloma Trial in Patients With Bone MetastasesWho this might be right forMultiple Myeloma Novartis Pharmaceuticals 179
Post-approval studies (Phase 4)Study completedNCT01474382What this trial is testingStudy of OraVerse® for Safety and Efficacy in Pediatric Dental PatientsWho this might be right forDental AnesthesiaAnesthesia, LocalAnesthesia, Reversal Novocol Pharmaceutical of Canada, Inc. 150
Large-scale testing (Phase 3)Looking for participantsNCT05473858What this trial is testingOraverse Versus LaserWho this might be right forReversal of Local Anesthesia in Children sara nabil 36
Not applicableNot Yet RecruitingNCT06620991What this trial is testingPre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus SurgeryWho this might be right forPreoperativePhentolamineIntraoperative+3 more Ain Shams University 60
Not applicableUnknownNCT04269980What this trial is testingPhentolamine Versus Magnesium Sulphate Infusion During Elective Lumbar Spine Surgery: a Randomized Double Blind Comparative StudyWho this might be right forMean Blood Pressure Beni-Suef University 30
Early research (Phase 1)Active Not RecruitingNCT03318094What this trial is testingRole of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in ObesityWho this might be right forInsulin ResistanceHealthyObesity Vanderbilt University Medical Center 36
Large-scale testing (Phase 3)Looking for participantsNCT05448807What this trial is testingEffectiveness of Phentolamine Mesylate as a Reversing Agent for Local Anesthesia in ChildrenWho this might be right forSoft Tissue Injuries Cairo University 100
Large-scale testing (Phase 3)Study completedNCT05646719What this trial is testingSafety and Efficacy of Nyxol Eye Drops as a Single Agent and With Adjunctive Low-Dose Pilocarpine Eye Drops in Subjects With PresbyopiaWho this might be right forPresbyopia Ocuphire Pharma, Inc. 333
Post-approval studies (Phase 4)Study completedNCT05687669What this trial is testingComparison Between the Use of Phentolamine Versus Glyceryl Trinitrate for Their Effect on Renal Function in Pre-eclampsia Patients in ICUWho this might be right forPre-Eclampsia; Complicating PregnancyPre-eclampsia Aggravated Assiut University 170
Testing effectiveness (Phase 2)Study completedNCT04024891What this trial is testingSafety and Efficacy of Ophthalmic Phentolamine Mesylate to Reverse Pharmacologically Induced MydriasisWho this might be right forMydriasisDilation Ocuphire Pharma, Inc. 32
Large-scale testing (Phase 3)Study completedNCT05134974What this trial is testingSafety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3)Who this might be right forMydriasisDilation Ocuphire Pharma, Inc. 368
Large-scale testing (Phase 3)Study completedNCT06542497What this trial is testingEvaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With PresbyopiaWho this might be right forPresbyopia Ocuphire Pharma, Inc. 569
Not applicableUnknownNCT06385600What this trial is testingIntravenous Labetalol vs Phentolamine for the Management of Severe Preeclampsia.Who this might be right forSevere Pre-eclampsia Assiut University 200
Large-scale testing (Phase 3)Study completedNCT05223478What this trial is testingNyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis in Pediatric SubjectsWho this might be right forMydriasisDilation Ocuphire Pharma, Inc. 23
Testing effectiveness (Phase 2)Study completedNCT04004507What this trial is testingSingle Dose Study of Phentolamine Mesylate Eye Drops in Patients With Severe Night Vision DisturbancesWho this might be right forDecrease in Night VisionDisturbance; Vision, Loss Ocuphire Pharma, Inc. 24
Not applicableNot Yet RecruitingNCT07012512What this trial is testingAdjusted Study Protocol: Within-Subject Paired-Eye Design Comparing Pilocarpine 0.1%, Phentolamine 0.75%, and Combination Therapy for Cyclopentolate Reversal in ChildrenWho this might be right forPupillary ConstrictionAccomodation Mansoura University 60
Testing effectiveness (Phase 2)Study completedNCT01703559What this trial is testingThe Safety and Efficacy of Phentolamine Mesylate Ophthalmic Solution in Subjects With Severe Night Vision DisturbancesWho this might be right forNight Vision ComplaintsDecrease in Night VisionDisturbance; Vision, Loss Ocuphire Pharma, Inc. 60
Large-scale testing (Phase 3)Study completedNCT04620213What this trial is testingSafety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced MydriasisWho this might be right forMydriasisDilation Ocuphire Pharma, Inc. 185
Not applicableStudy completedNCT03033537What this trial is testingIntracavernosal Injection of Papaverine/Verapamil Versus Papaverine/Phentolamine in Erectile DysfunctionWho this might be right forErectile Dysfunction Adam International Hospital 20