Not applicableNot Yet RecruitingNCT06385600What this trial is testingIntravenous Labetalol vs Phentolamine for the Management of Severe Preeclampsia.Who this might be right forSevere Pre-eclampsia Assiut University 200
Post-approval studies (Phase 4)Study completedNCT00104104What this trial is testingA Multiple Myeloma Trial in Patients With Bone MetastasesWho this might be right forMultiple Myeloma Novartis Pharmaceuticals 179
Large-scale testing (Phase 3)Looking for participantsNCT05448807What this trial is testingEffectiveness of Phentolamine Mesylate as a Reversing Agent for Local Anesthesia in ChildrenWho this might be right forSoft Tissue Injuries Cairo University 100
Not applicableNot Yet RecruitingNCT06620991What this trial is testingPre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus SurgeryWho this might be right forPreoperativePhentolamineIntraoperative+3 more Ain Shams University 60
Not applicableNot Yet RecruitingNCT07012512What this trial is testingAdjusted Study Protocol: Within-Subject Paired-Eye Design Comparing Pilocarpine 0.1%, Phentolamine 0.75%, and Combination Therapy for Cyclopentolate Reversal in ChildrenWho this might be right forPupillary ConstrictionAccomodation Mansoura University 60
Not applicableStudy completedNCT03740386What this trial is testingPhentolamine Mesylate as a Reversal of Local AnesthesicsWho this might be right forAnesthesia, Local León Formación 90
Early research (Phase 1)Active Not RecruitingNCT03318094What this trial is testingRole of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in ObesityWho this might be right forInsulin ResistanceHealthyObesity Vanderbilt University Medical Center 36
Large-scale testing (Phase 3)Study completedNCT06542497What this trial is testingEvaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With PresbyopiaWho this might be right forPresbyopia Ocuphire Pharma, Inc. 569
Very early researchUnknownNCT04110808What this trial is testingComparative Effect of Hypotensive Anaesthesia on Event Related Potentials, Quantitative ElectroencephalograghyWho this might be right forEffect of Drugs Beni-Suef University 60
Post-approval studies (Phase 4)Study completedNCT01474382What this trial is testingStudy of OraVerse® for Safety and Efficacy in Pediatric Dental PatientsWho this might be right forDental AnesthesiaAnesthesia, LocalAnesthesia, Reversal Novocol Pharmaceutical of Canada, Inc. 150
Large-scale testing (Phase 3)Study completedNCT04638660What this trial is testingSafety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) in Subjects With Dim Light Vision DisturbancesWho this might be right forDim Light Vision Disturbances Ocuphire Pharma, Inc. 144
Not applicableUnknownNCT04269980What this trial is testingPhentolamine Versus Magnesium Sulphate Infusion During Elective Lumbar Spine Surgery: a Randomized Double Blind Comparative StudyWho this might be right forMean Blood Pressure Beni-Suef University 30
Testing effectiveness (Phase 2)Study completedNCT01703559What this trial is testingThe Safety and Efficacy of Phentolamine Mesylate Ophthalmic Solution in Subjects With Severe Night Vision DisturbancesWho this might be right forNight Vision ComplaintsDecrease in Night VisionDisturbance; Vision, Loss Ocuphire Pharma, Inc. 60
Large-scale testing (Phase 3)Looking for participantsNCT07140783What this trial is testingOPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual AcuityWho this might be right forVision Loss NightVision Disorders Ocuphire Pharma, Inc. 200
Large-scale testing (Phase 3)UnknownNCT06286059What this trial is testingEfficacy of Phentolamine in Prevention of Contrast-Associated Acute Kidney Injury After Complex PCIWho this might be right forCA-AKI - Contrast-Associated Acute Kidney InjuryCoronary Artery DiseaseAcute Coronary Syndrome+1 more Helwan University 60
Large-scale testing (Phase 3)Study completedNCT06349759What this trial is testingSafety and Efficacy of 0.75% Phentolamine Ophthalmic Solution in Subjects With Post-refractive Surgery Visual DisturbancesWho this might be right forMesopic VisionNight Vision Loss Ocuphire Pharma, Inc. 200
Large-scale testing (Phase 3)Study completedNCT05646719What this trial is testingSafety and Efficacy of Nyxol Eye Drops as a Single Agent and With Adjunctive Low-Dose Pilocarpine Eye Drops in Subjects With PresbyopiaWho this might be right forPresbyopia Ocuphire Pharma, Inc. 333
Large-scale testing (Phase 3)Study completedNCT04620213What this trial is testingSafety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced MydriasisWho this might be right forMydriasisDilation Ocuphire Pharma, Inc. 185
Testing effectiveness (Phase 2)Study completedNCT00080808What this trial is testingNerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate CancerWho this might be right forProstate Cancer M.D. Anderson Cancer Center 111
Large-scale testing (Phase 3)Study completedNCT05223478What this trial is testingNyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis in Pediatric SubjectsWho this might be right forMydriasisDilation Ocuphire Pharma, Inc. 23