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Results for “Phentolamine”

29 trials

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Showing 20 of 29 results

Large-scale testing (Phase 3)Study completedNCT05646719
What this trial is testing

Safety and Efficacy of Nyxol Eye Drops as a Single Agent and With Adjunctive Low-Dose Pilocarpine Eye Drops in Subjects With Presbyopia

Who this might be right for
Presbyopia
Ocuphire Pharma, Inc. 333
Large-scale testing (Phase 3)Study completedNCT05134974
What this trial is testing

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3)

Who this might be right for
MydriasisDilation
Ocuphire Pharma, Inc. 368
Testing effectiveness (Phase 2)Study completedNCT04675151
What this trial is testing

Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia

Who this might be right for
Presbyopia
Ocuphire Pharma, Inc. 150
Large-scale testing (Phase 3)Study completedNCT04638660
What this trial is testing

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) in Subjects With Dim Light Vision Disturbances

Who this might be right for
Dim Light Vision Disturbances
Ocuphire Pharma, Inc. 144
Testing effectiveness (Phase 2)Study completedNCT00080808
What this trial is testing

Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer

Who this might be right for
Prostate Cancer
M.D. Anderson Cancer Center 111
Post-approval studies (Phase 4)Study completedNCT05687669
What this trial is testing

Comparison Between the Use of Phentolamine Versus Glyceryl Trinitrate for Their Effect on Renal Function in Pre-eclampsia Patients in ICU

Who this might be right for
Pre-Eclampsia; Complicating PregnancyPre-eclampsia Aggravated
Assiut University 170
Large-scale testing (Phase 3)Study completedNCT06542497
What this trial is testing

Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia

Who this might be right for
Presbyopia
Ocuphire Pharma, Inc. 569
Testing effectiveness (Phase 2)Study completedNCT04004507
What this trial is testing

Single Dose Study of Phentolamine Mesylate Eye Drops in Patients With Severe Night Vision Disturbances

Who this might be right for
Decrease in Night VisionDisturbance; Vision, Loss
Ocuphire Pharma, Inc. 24
Not applicableNot Yet RecruitingNCT06620991
What this trial is testing

Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus Surgery

Who this might be right for
PreoperativePhentolamineIntraoperative+3 more
Ain Shams University 60
Large-scale testing (Phase 3)Looking for participantsNCT05473858
What this trial is testing

Oraverse Versus Laser

Who this might be right for
Reversal of Local Anesthesia in Children
sara nabil 36
Testing effectiveness (Phase 2)Study completedNCT04024891
What this trial is testing

Safety and Efficacy of Ophthalmic Phentolamine Mesylate to Reverse Pharmacologically Induced Mydriasis

Who this might be right for
MydriasisDilation
Ocuphire Pharma, Inc. 32
Large-scale testing (Phase 3)Study completedNCT05223478
What this trial is testing

Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis in Pediatric Subjects

Who this might be right for
MydriasisDilation
Ocuphire Pharma, Inc. 23
Not applicableNot Yet RecruitingNCT07012512
What this trial is testing

Adjusted Study Protocol: Within-Subject Paired-Eye Design Comparing Pilocarpine 0.1%, Phentolamine 0.75%, and Combination Therapy for Cyclopentolate Reversal in Children

Who this might be right for
Pupillary ConstrictionAccomodation
Mansoura University 60
Not applicableUnknownNCT06385600
What this trial is testing

Intravenous Labetalol vs Phentolamine for the Management of Severe Preeclampsia.

Who this might be right for
Severe Pre-eclampsia
Assiut University 200
Very early researchUnknownNCT04110808
What this trial is testing

Comparative Effect of Hypotensive Anaesthesia on Event Related Potentials, Quantitative Electroencephalograghy

Who this might be right for
Effect of Drugs
Beni-Suef University 60
Large-scale testing (Phase 3)Study completedNCT04620213
What this trial is testing

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis

Who this might be right for
MydriasisDilation
Ocuphire Pharma, Inc. 185
Large-scale testing (Phase 3)Looking for participantsNCT07140783
What this trial is testing

OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual Acuity

Who this might be right for
Vision Loss NightVision Disorders
Ocuphire Pharma, Inc. 580
Large-scale testing (Phase 3)UnknownNCT06286059
What this trial is testing

Efficacy of Phentolamine in Prevention of Contrast-Associated Acute Kidney Injury After Complex PCI

Who this might be right for
CA-AKI - Contrast-Associated Acute Kidney InjuryCoronary Artery DiseaseAcute Coronary Syndrome+1 more
Helwan University 60
Testing effectiveness (Phase 2)Study completedNCT03960866
What this trial is testing

Safety and Efficacy of Ophthalmic Phentolamine Mesylate in Glaucoma

Who this might be right for
Open Angle GlaucomaOcular Hypertension
Ocuphire Pharma, Inc. 39
Not applicableUnknownNCT04269980
What this trial is testing

Phentolamine Versus Magnesium Sulphate Infusion During Elective Lumbar Spine Surgery: a Randomized Double Blind Comparative Study

Who this might be right for
Mean Blood Pressure
Beni-Suef University 30
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