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Results for “Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic Leukemia”

83 trials

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Showing 20 of 83 results

Not applicableLooking for participantsNCT05750706
What this trial is testing

Incidence of Invasive Fungal Infections Among Patients With Acute Lymphoblastic Leukemia Ph-negative

Who this might be right for
Acute Lymphoblastic Leukemia, AdultInvasive Fungal Infections
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 150
Not applicableEnded earlyNCT00008216
What this trial is testing

Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer

Who this might be right for
Adult Langerhans Cell HistiocytosisChildhood Langerhans Cell HistiocytosisLeukemia+4 more
Columbia University 48
Early research (Phase 1)Study completedNCT00005092
What this trial is testing

Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Who this might be right for
LeukemiaLymphomaMultiple Myeloma and Plasma Cell Neoplasm+1 more
M.D. Anderson Cancer Center 7
Early research (Phase 1)Study completedNCT00352677
What this trial is testing

Safety and Tolerability Study of INNO-406 to Treat Chronic Myeloid Leukemia or Acute Lymphocytic Leukemia

Who this might be right for
Chronic Myeloid LeukemiaAcute Lymphocytic Leukemia
CytRx 100
Testing effectiveness (Phase 2)UnknownNCT04688983
What this trial is testing

Study in Adult Ph-positive ALL

Who this might be right for
Acute Lymphoblastic Leukemia, Adult
Cardiff University 180
Testing effectiveness (Phase 2)Ended earlyNCT04554459
What this trial is testing

Ponatinib Plus Reduced-intensity Chemotherapy in the First-line Treatment of Adult Patients With Ph+ ALL

Who this might be right for
Acute Lymphoblastic Leukemia, AdultPh+ ALLNewly Diagnosed
Institute of Hematology and Blood Transfusion, Czech Republic 4
Early research (Phase 1)Ended earlyNCT02819804
What this trial is testing

Nivolumab and Dasatinib in Treating Patients With Relapsed or Refractory Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia With t(9;22)(q34;q11.2); BCR-ABL1Recurrent Adult Acute Lymphoblastic LeukemiaRecurrent Childhood Acute Lymphoblastic Leukemia+2 more
Northwestern University 1
Testing effectiveness (Phase 2)Study completedNCT00109707
What this trial is testing

Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies

Who this might be right for
Chronic Myelogenous LeukemiaAcute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)Hypereosinophilic Syndrome+1 more
Novartis Pharmaceuticals 507
Large-scale testing (Phase 3)Study completedNCT00265837
What this trial is testing

Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+3 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 72
Not applicableUnknownNCT05026229
What this trial is testing

Dasatinib Plus Reduced Intensive Consolidation Chemotherapy in Ph+ Adult ALL

Who this might be right for
Precursor Cell Lymphoblastic Leukemia-LymphomaPhiladelphia-Positive Acute Lymphoblastic LeukemiaALL, Adult
First Affiliated Hospital Xi'an Jiaotong University 60
Large-scale testing (Phase 3)Active Not RecruitingNCT02003222
What this trial is testing

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
National Cancer Institute (NCI) 488
Testing effectiveness (Phase 2)Study completedNCT01256398
What this trial is testing

Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAdult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
National Cancer Institute (NCI) 66
Not applicableLooking for participantsNCT04179929
What this trial is testing

Treatment of Breakpoint Cluster Region-Abelson (BCR-ABL) Negative ALL in Adults

Who this might be right for
Acute Lymphoblastic Leukemia
PETHEMA Foundation 300
Testing effectiveness (Phase 2)Active Not RecruitingNCT01424982
What this trial is testing

Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Lymphoblastic LeukemiaAdult Acute Lymphoblastic Leukemia in Complete Remission+4 more
M.D. Anderson Cancer Center 88
Early research (Phase 1)Study completedNCT00357708
What this trial is testing

Vorinostat and Decitabine in Treating Patients With Relapsed, Refractory, or Poor-Prognosis Hematologic Cancer or Other Diseases

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+10 more
National Cancer Institute (NCI) 50
Very early researchStudy completedNCT01184885
What this trial is testing

A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy

Who this might be right for
Lymphoid Malignancies (New or Relapsed)Acute Lymphoblastic LeukemiaBurkitt Lymphoma+3 more
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 7
Not applicableUnknownNCT05024357
What this trial is testing

TKI Maintenance Therapy Following Allo-HSCT in Newly Diagnosed Ph+ Adult ALL

Who this might be right for
Precursor Cell Lymphoblastic Leukemia-LymphomaPhiladelphia-Positive Acute Lymphoblastic LeukemiaALL, Adult
First Affiliated Hospital Xi'an Jiaotong University 80
Large-scale testing (Phase 3)Looking for participantsNCT04994717
What this trial is testing

Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

Who this might be right for
Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Amgen 304
Testing effectiveness (Phase 2)UnknownNCT02744768
What this trial is testing

D-ALBA Frontline Sequential Dasatinib and Blinatumomab in Adult Philadelphia Positive Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 60
Early research (Phase 1)Study completedNCT00114257
What this trial is testing

Decitabine and FR901228 in Treating Patients With Relapsed or Refractory Leukemia, Myelodysplastic Syndromes, or Myeloproliferative Disorders

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaMyelodysplastic Syndromes+1 more
National Cancer Institute (NCI) 36
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