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Results for “Phosphoric Diester Hydrolases”

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Showing 20 of 0 results

Not applicableStudy completedNCT07690566
What this trial is testing

Ultrasonic Enhancement Delivery of Phosphodiesterase Inhibitors Nanoparticles for Diabetic Management of the Foot

Who this might be right for
Diabetic FootWound Healing DelayedDiabete Mellitus+1 more
Deraya University 1
Early research (Phase 1)Study completedNCT02840279
What this trial is testing

A Multiple Ascending Dose Study of BPN14770 in Healthy Young and Elderly Male or Female Subjects

Who this might be right for
Alzheimer's Disease
Tetra Discovery Partners 77
Large-scale testing (Phase 3)Study completedNCT00125918
What this trial is testing

PHIRST-1: Tadalafil in the Treatment of Pulmonary Arterial Hypertension

Who this might be right for
Pulmonary Hypertension
Eli Lilly and Company 406
Large-scale testing (Phase 3)Study completedNCT00348101
What this trial is testing

Effects of Beta-Blocker Therapy and Phosphodiesterase Inhibition on Cardiac Neurohormonal Activation

Who this might be right for
Coronary Artery Disease
Klinikum Ludwigshafen 75
Testing effectiveness (Phase 2)Study completedNCT05343637
What this trial is testing

A Dose Escalation Study to Evaluate the Effect of RT234 in Subjects With Pulmonary Arterial Hypertension

Who this might be right for
Pulmonary Arterial Hypertension
Respira Therapeutics, Inc. 14
Not applicableStudy completedNCT01150903
What this trial is testing

Identification of Underlying Conditions in Men Prescribed a PDE5 Inhibitor

Who this might be right for
Erectile DysfunctionCardiovascular DiseasesMale Urogenital Diseases
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 98,832
Not applicableStudy completedNCT01392638
What this trial is testing

Effects of Sildenafil in Resistant Hypertensives and Genetic Polymorphism

Who this might be right for
Hypertension
University of Campinas, Brazil 120
Testing effectiveness (Phase 2)Study completedNCT00317421
What this trial is testing

Effect of Regular Sildenafil on Blood Pressure and Arterial Function in Hypertension

Who this might be right for
Hypertension
University of Edinburgh 20
Not applicableWithdrawnNCT04344678
What this trial is testing

The Phosphodiesterase 5 Inhibitor Sildenafil as an Adjunct to Antidepressants in Major Depressive Disorder Patients

Who this might be right for
Major Depressive Disorder
Sadat City University
Testing effectiveness (Phase 2)Study completedNCT00422461
What this trial is testing

A Dose Finding Study Of PF-00489791 In Patients With Mild To Moderate High Blood Pressure

Who this might be right for
Hypertension
Pfizer 135
Not applicableStudy completedNCT07745179
What this trial is testing

Natural History Study: ENPP1 Deficiency or the Early-Onset Form of ABCC6 Deficiency

Who this might be right for
Ectonucleotide Pyrophosphatase/phosphodiesterase1 DeficiencyATP-Binding Cassette Subfamily C Member 6 DeficiencyGeneralized Arterial Calcification of Infancy+2 more
Inozyme Pharma 23
Early research (Phase 1)Ended earlyNCT02907294
What this trial is testing

Study to Assess the Safety, Tolerability and Pharmacokinetic Profile of PBF-999 "After Multiple Oral Doses" in Healthy Volunteers

Who this might be right for
Huntington Disease
Palobiofarma SL 8
Very early researchStudy completedNCT02956148
What this trial is testing

Follow-up Measurement of Brain PDE10A Enzyme Levels in Huntington´s Disease Gene Expansion Carriers

Who this might be right for
Huntington's Disease
CHDI Foundation, Inc. 45
Not applicableStudy completedNCT00599235
What this trial is testing

Sildenafil and Exercise Capacity in Hypertension

Who this might be right for
Hypertension
University of Edinburgh 30
Early research (Phase 1)Ended earlyNCT01215552
What this trial is testing

Study of the Inhibition of [11C]R-rolipram Binding to Brain Phosphodiesterase - 4 (PDE-4) by HT-0712

Who this might be right for
Healthy Elderly Volunteers
Dart NeuroScience, LLC 3
Not applicableStudy completedNCT04841187
What this trial is testing

Assessing the Long Term Effectiveness and Safety of Systemic Treatments in Cutaneous Psoriasis

Who this might be right for
Psoriasis
Assistance Publique - Hôpitaux de Paris 2,000
Testing effectiveness (Phase 2)Looking for participantsNCT07209462
What this trial is testing

Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM)

Who this might be right for
Fragile X Syndrome
Mirum Pharmaceuticals, Inc. 60
Early research (Phase 1)Study completedNCT03030105
What this trial is testing

Study to Evaluate the Effects of BPN14770 on Scopolamine-induced Cognitive Impairment in Healthy Volunteers

Who this might be right for
Alzheimer Disease
Tetra Discovery Partners 38
Large-scale testing (Phase 3)Looking for participantsNCT05844462
What this trial is testing

Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease

Who this might be right for
Pulmonary HypertensionChronic Obstructive Pulmonary Disease
Assistance Publique - Hôpitaux de Paris 200
Not applicableWithdrawnNCT05458232
What this trial is testing

Use of a Phosphodiesterase Type 5 Inhibitor to Improve Anabolic Resistance in Older Adults

Who this might be right for
Sarcopenia
University of Arkansas
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