Post-approval studies (Phase 4)Study completedNCT02138539What this trial is testingEvaluation of an Herbal-Based De-Pigmenting SystemWho this might be right forMelasmaHyperpigmentation Sadick Research Group 28
Not applicableStudy completedNCT06453837What this trial is testingClinical Study for the Efficacy Evaluation of a Food SupplementWho this might be right forSpot PigmentedWrinkle Mibelle Group Biochemistry 110
Not applicableActive Not RecruitingNCT07477275What this trial is testingCombination of Oral and Topical Whitening Agents for Reducing Skin PigmentationWho this might be right forDark Spots USMARI Research & Innovation Centre 68
Not applicableNot Yet RecruitingNCT07324759What this trial is testingClinical Study to Assess Safety, Effectiveness and In-Use Tolerability of Saffron Extract Capsules for Improving Skin Health and Reducing Signs of Aging on Healthy Adult Male and Female Subjects.Who this might be right forWrinklesFine LinesHyperpigmentation+1 more NovoBliss Research Pvt Ltd 50
Not applicableStudy completedNCT05793619What this trial is testingTolerance and Performance (Mode of Administration) of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown SpotsWho this might be right forLentigo SolarSenile Lentigo Cryonove Pharma 20
Not applicableStudy completedNCT06361251What this trial is testingInterventional, Monocentric, Double-blind Randomized Category 2b Study Evaluating the Evaluation of the Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post -Inflammatory Hyperpigmentation (Pih)) on the FaceWho this might be right forLentigoSolar LentigoPost Inflammatory Hyperpigmentation Cryonove Pharma 30
Not applicableStudy completedNCT05600049What this trial is testingTolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown SpotsWho this might be right forLentigo Solar Cryonove Pharma 33
Testing effectiveness (Phase 2)Study completedNCT00107965What this trial is testingStudy to Determine the Safety of Two Applications of PEP005 Topical Gel to Actinic KeratosesWho this might be right forActinic Keratosis Peplin 60
Not applicableStudy completedNCT01444989What this trial is testingDevelopment and Validation of a Quality of Life Instrument for Actinic KeratosisWho this might be right forActinic Keratosis Wake Forest University 150
Post-approval studies (Phase 4)Study completedNCT01149876What this trial is testingStudy to Evaluate the Effect of a Nu Skin Product and Device for Brown SpotsWho this might be right forHyperpigmentation Massachusetts General Hospital 80
Not applicableUnknownNCT05808842What this trial is testingLaser Treatment for Facial and Neck RejuvenationWho this might be right forFace RejuvenationNeck Rejuvenation Goldman, Butterwick, Fitzpatrick and Groff 15
Not applicableStudy completedNCT07040345What this trial is testingAnnurca Apple Peel Oleolite for the Treatment of Skin HyperpigmentationWho this might be right forHyperpigmentationMelasmaSkin Spots+1 more Ritamaria Di Lorenzo 48
Not applicableStudy completedNCT06640244What this trial is testingThe Effect of Cosmetic Face Care Products on Facial Skin Tone and Spot BrighteningWho this might be right forPigment Spots Unilever R&D 250
Not applicableUnknownNCT05595525What this trial is testingLaser Treatment to Improve Skin QualityWho this might be right forSkin Quality Goldman, Butterwick, Fitzpatrick and Groff 20
Not applicableUnknownNCT06305897What this trial is testingEvaluation of the Tolerance (Main Objective) and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-inflammatory Hyperpigmentation) on the FaceWho this might be right forLentigoSolar LentigoPost Inflammatory Hyperpigmentation Cryonove Pharma 45
Testing effectiveness (Phase 2)Study completedNCT00239135What this trial is testingStudy to Determine the Maximum Tolerated Dose and Safety of PEP005 Topical GelWho this might be right forKeratosis Peplin 34
Not applicableUnknownNCT01136629What this trial is testingClinical, Histological and Biochemical Characterization of Hyperpigmented LesionWho this might be right forLentigoMelasma National University Hospital, Singapore 160
Not applicableStudy completedNCT07054710What this trial is testingEvaluation of the Efficacy of a Cosmetic Light MaskWho this might be right forFine LinesContourSagging Skin+5 more Therabody, Inc. 115
Not applicableStudy completedNCT07468175What this trial is testingA 16-week Clinical Study Investigating a Dark Spot Corrector Serum in Women With Moderate Discrete HyperpigmentationWho this might be right forHyperpigmentationDark Spots Revision Skincare 48
Not applicableUnknownNCT05883657What this trial is testingTolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-Inflammatory Hyperpigmentation)Who this might be right forSolar LentigoSenile LentigoPost Inflammatory Hyperpigmentation Cryonove Pharma 80