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Results for “Platelet Derived Growth Factor”

56 trials

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Showing 20 of 56 results

Not applicableStudy completedNCT00667134
What this trial is testing

Stimulatory Autoantibodies to the Platelet-Derived Growth Factor Receptor (PDGFR) in Patients With Systemic Sclerosis

Who this might be right for
Systemic Sclerosis
University of Michigan 26
Testing effectiveness (Phase 2)WithdrawnNCT02747797
What this trial is testing

Lucitanib (E3810) in Patients With Advanced Cancer and FGFR, VEGFR, or PDGFR Pathway Aberrations

Who this might be right for
Advanced Cancer
Teresa Helsten, MD
Not applicableStudy completedNCT00518102
What this trial is testing

The Risk of Cancer in Users of Regranex (Becaplermin) and Matched Comparators (Nonusers of Regranex [Becaplermin])

Who this might be right for
Diabetes Mellitus
Ethicon, Inc. 4,431
Not applicableStudy completedNCT00038675
What this trial is testing

Therapy of HES, PV, Atypical Chronic Myelocytic Leukemia (CML) or Chronic Myelomonocytic Leukemia (CMML), and Mastocytosis With Imatinib Mesylate

Who this might be right for
Chronic Myelomonocytic LeukemiaChronic Myeloid LeukemiaPolycythemia Vera+2 more
M.D. Anderson Cancer Center 125
Testing effectiveness (Phase 2)Study completedNCT00867334
What this trial is testing

New Individualized Therapy Trial for Metastatic Colorectal Cancer

Who this might be right for
Colorectal NeoplasmColorectal Cancer
Inova Health Care Services 10
Early research (Phase 1)Study completedNCT06137482
What this trial is testing

See How Safe and Tolerable Different Doses of REGN13335 Are When Administered Intravenously (IV) or Subcutaneously (SC) to Healthy Adult Participants

Who this might be right for
Healthy Volunteers
Regeneron Pharmaceuticals 56
Testing effectiveness (Phase 2)Ended earlyNCT03352427
What this trial is testing

Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations

Who this might be right for
GliomaHigh Grade GliomaPontine Tumors
University of Michigan Rogel Cancer Center 3
Large-scale testing (Phase 3)Study completedNCT00970697
What this trial is testing

Becaplermin Gel for MARTORELL's Hypertensive Leg Ulcers

Who this might be right for
MARTORELL'S ULCERHypertensive Leg UlcerNecrotic Angiodermatitis
Assistance Publique - Hôpitaux de Paris 64
Early research (Phase 1)Study completedNCT01051700
What this trial is testing

A Safety Study in Healthy Volunteers to Evaluate Safety, How Fast the Drug is Absorbed, and the Side Effects of the Drug in Humans

Who this might be right for
Macular Degeneration
GlaxoSmithKline 72
Testing effectiveness (Phase 2)Ended earlyNCT00495625
What this trial is testing

Sunitinib Malate (SUO11248) In Subjects W/ Metastatic And/Or Surgically Unresectable Hepatocellular Cancers (HCC)

Who this might be right for
Liver Cancer
H. Lee Moffitt Cancer Center and Research Institute 33
Testing effectiveness (Phase 2)WithdrawnNCT00159016
What this trial is testing

Role of Glivec in Patients With Tumor Cells Positive for C-kit or PDGFR; a Multi Center Study.

Who this might be right for
Metastatic Solid Tumors.
Hadassah Medical Organization 100
Early research (Phase 1)UnknownNCT01175109
What this trial is testing

Study of Imatinib, a Platelet-derived Growth Factor Receptor Inhibitor, and LBH589, a Histone Deacetylase Inhibitor, in the Treatment of Newly Diagnosed and Recurrent Chordoma

Who this might be right for
Chordoma
Deric M Park MD 36
Not applicableStudy completedNCT07287475
What this trial is testing

Application of Growth Factors Derived From Platelets to Accelerate Healing and Reduce Post-extraction Complications in Diabetic Individuals

Who this might be right for
Diabete Mellitus
King Abdulaziz University 7
Not applicableStudy completedNCT01235260
What this trial is testing

Becaplermin Use and Cancer Risk in a Patient Population of U.S. Veterans With Diabetes

Who this might be right for
Diabetes MellitusFoot UlcerDiabetic Foot+1 more
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Not applicableLooking for participantsNCT04954664
What this trial is testing

Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor

Who this might be right for
Dental ImplantBone Loss
University of Alabama at Birmingham 44
Testing effectiveness (Phase 2)Study completedNCT00117299
What this trial is testing

PTK787/ZK222584 in the Treatment of Metastatic Gastrointestinal Stromal Tumors Resistant to Imatinib

Who this might be right for
Sarcoma
University of Helsinki 45
Not applicableStudy completedNCT05178771
What this trial is testing

Efficacy of PRF Application on Clinical Parameters and GCF Platelet-derived Growth Factor-BB and Periostin Levels

Who this might be right for
Periodontitis
University of Baghdad 14
Early research (Phase 1)WithdrawnNCT01568645
What this trial is testing

Imatinib and Carvedilol for High Blood Pressure in the Lungs in Adults With Sickle Cell Disease

Who this might be right for
Pulmonary Hypertension
National Heart, Lung, and Blood Institute (NHLBI)
Testing effectiveness (Phase 2)Study completedNCT03797326
What this trial is testing

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)

Who this might be right for
Advanced Solid TumorsTriple Negative Breast CancerOvarian Cancer+5 more
Merck Sharp & Dohme LLC 611
Not applicableLooking for participantsNCT06956560
What this trial is testing

Platelet Derived Growth Factor Receptor ß (PDGFRß) Imaging in Cardiac Fibrosis

Who this might be right for
ST-Elevation Myocardial Infarction (STEMI)Heart Failure With Preserved Ejection Fraction (HFpEF)
Uppsala University 30
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