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Results for “Polyneuropathy, Amyloid”

218 trials

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Showing 20 of 218 results

Testing effectiveness (Phase 2)Study completedNCT02595983
What this trial is testing

The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant

Who this might be right for
Transthyretin (TTR)-Mediated AmyloidosisFamilial Amyloidotic Polyneuropathy (FAP)ATTR Amyloidosis+1 more
Alnylam Pharmaceuticals 12
Not applicableLooking for participantsNCT07154394
What this trial is testing

Cardiac Amyloid Deposits and Heart Dysfunction in Alzheimer's Disease

Who this might be right for
Dementia, Alzheimer TypeMild Cognitive ImpairmentCardiac Amyloidosis
University Hospital, Essen 15
Large-scale testing (Phase 3)Study completedNCT04298372
What this trial is testing

Frontline Lenalidomide for AL Amyloidosis Involving Myocardium

Who this might be right for
Amyloidosis Cardiac
Seoul National University Hospital 2
Large-scale testing (Phase 3)Looking for participantsNCT06672237
What this trial is testing

NTLA-2001 in ATTRv-PN

Who this might be right for
Neuromuscular DiseaseNeuromuscular Diseases (NMD)Neurodegenerative Disease+17 more
Intellia Therapeutics 60
Not applicableStudy completedNCT03616496
What this trial is testing

Assessment of 18F-Florbetaben Whole-body PET for the Detection of Cardiac and Extracardiac Sites of Amyloid Deposits

Who this might be right for
Cardiac Amyloidosis
Central Hospital, Nancy, France 67
Not applicableLooking for participantsNCT06866912
What this trial is testing

Observational Epidemiological Study of Patients Suffering From Systemic Amyloidosis

Who this might be right for
Cardiomyopathy
IRCCS Azienda Ospedaliero-Universitaria di Bologna 750
Not applicableStudy completedNCT03190577
What this trial is testing

Assessment of the Prevalence of TTR Amyloid Neuropathy in a Population of Patients With Neuropathy of Unknown Aetiology

Who this might be right for
Familial Amyloid NeuropathyTransthyretin Amyloidosis
Nantes University Hospital 400
Large-scale testing (Phase 3)Study completedNCT02791230
What this trial is testing

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 1,733
Not applicableLooking for participantsNCT07382128
What this trial is testing

Myocardial Perfusion CMR for Differentiating and Characterizing Hypertrophic Cardiomyopathy Phenotypes

Who this might be right for
HCM - Hypertrophic CardiomyopathyAnderson Fabry DiseaseCardiac Magnetic Resonance Imaging+1 more
IRCCS Azienda Ospedaliero-Universitaria di Bologna 250
Large-scale testing (Phase 3)Study completedNCT03860935
What this trial is testing

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+2 more
Eidos Therapeutics, a BridgeBio company 632
Not applicableUnknownNCT04061213
What this trial is testing

ATTR Amyloidosis in Elderly Patients With Aortic Stenosis

Who this might be right for
Aortic Stenosis SymptomaticAmyloidosis Cardiac
Insel Gruppe AG, University Hospital Bern 489
Very early researchUnknownNCT05263817
What this trial is testing

A Clinical Study of CD19/BCMA CAR-T Cells in the Treatment of Refractory POEMS Syndrome, Amyloidosis, Autoimmune Hemolytic Anemia, and Vasculitis

Who this might be right for
POEMS SyndromeAmyloidosisAutoimmune Hemolytic Anemia+1 more
Zhejiang University 75
Not applicableStudy completedNCT03029026
What this trial is testing

The Role of Occult Cardiac Amyloid in the Elderly With Aortic Stenosis.

Who this might be right for
Cardiac AmyloidosisAortic Stenosis
Queen Mary University of London 581
Not applicableNot Yet RecruitingNCT07567508
What this trial is testing

Early Detection of Concealed Cardiac Amyloidosis Using AI-ECG and CT-Derived Extracellular Volume in Patients With Atrial Fibrillation

Who this might be right for
Atrial Fibrillation (AF)Cardiac Amyloidosis
Samsung Medical Center 500
Testing effectiveness (Phase 2)UnknownNCT06539208
What this trial is testing

A Phase I/IIa，Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis PolyneuropathyTransthyrexin Amyloidosis Cardiomyopathy
YolTech Therapeutics Co., Ltd 31
Not applicableLooking for participantsNCT06458374
What this trial is testing

ATTR Cardiac Amyloidosis in a Selected Population

Who this might be right for
ATTR Amyloidosis Wild TypeATTR Gene MutationCarpal Tunnel Syndrome+1 more
Helse Møre og Romsdal HF 180
Not applicableActive Not RecruitingNCT06040567
What this trial is testing

Polyneuropathy, Impairments and Physical Activity - The PolyImPAct Study

Who this might be right for
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)Vasculitic NeuropathyPOEMS Syndrome+6 more
Rigshospitalet, Denmark 520
Large-scale testing (Phase 3)Study completedNCT04136184
What this trial is testing

NEURO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

Who this might be right for
Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
Ionis Pharmaceuticals, Inc. 168
Not applicableUnknownNCT04146415
What this trial is testing

Diagnosis of Cardiac Amyloidosis With 99mTc-PYP; Comparison Between Planar Imaging, SPECT/CT and Cardiac-dedicated CZT Camera

Who this might be right for
Cardiac Amyloidosis
Tel-Aviv Sourasky Medical Center 30
Post-approval studies (Phase 4)Study completedNCT04828993
What this trial is testing

The Effect Of Tafamidis Meglumine In Transthyretin Amyloid Polyneuropathy Patients

Who this might be right for
Transthyretin Amyloid Polyneuropathy (ATTR-PN)
Pfizer 15
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