Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Preserved Ejection Fraction”

593 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 593 results

Not applicableLooking for participantsNCT05784753
What this trial is testing

HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction

Who this might be right for
HFpEF - Heart Failure With Preserved Ejection Fraction
University of Nebraska 300
Not applicableStudy completedNCT05002075
What this trial is testing

Efficacy of an m-Health Cardiac Rehabilitation Program in Heart Failure With Preserved Ejection Fraction

Who this might be right for
Heart Failure With Preserved Ejection Fraction
University of Texas Southwestern Medical Center 69
Large-scale testing (Phase 3)Looking for participantsNCT06200207
What this trial is testing

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

Who this might be right for
Heart FailureSystemic Inflammation
Novo Nordisk A/S 680
Testing effectiveness (Phase 2)WithdrawnNCT05312021
What this trial is testing

Selective PDE9 Inhibition With IMR-687 in Adults With Heart Failure With Preserved Ejection Fraction

Who this might be right for
Heart Failure With Preserved Ejection Fraction
Cardurion Pharmaceuticals, Inc.
Not applicableNot Yet RecruitingNCT06655532
What this trial is testing

Effects of an Exercise Program in Women Over 60 yr. With HFpEF and Sarcopenia on Functional Capacity and Quality of Life

Who this might be right for
Heart Failure With Preserved Ejection Fraction (HFpEF)SarcopeniaWomen
Fundación para la Investigación del Hospital Clínico de Valencia 40
Not applicableUnknownNCT02649400
What this trial is testing

Assessment of Functional Capacity and Inflammatory Markers in Women With Heart Failure With Preserved Ejection Fraction

Who this might be right for
Heart Failure, DiastolicCoronary Artery DiseaseInflammation
Federal University of São Paulo 50
Not applicableNot Yet RecruitingNCT07324772
What this trial is testing

PREACTIVE: Preconditioning Exercise Intervention to Improve Symptoms and Quality of Life in Comorbid Atrial Fibrillation and HFpEF

Who this might be right for
Atrial Fibrillation (AF)Atrial Fibrillation (Paroxysmal)Persistent Atrial Fibrillation+1 more
Northwestern University 30
Not applicableUnknownNCT04594499
What this trial is testing

The Relationship Between Pericardial Fat Thickness and Arterial Stiffness in HFpEF Patients

Who this might be right for
Heart Failure With Preserved Ejection Fraction
Chongqing Medical University 200
Not applicableStudy completedNCT03968601
What this trial is testing

Use of Pre-operative Global Longitudinal Strain to Predict Post-operative Left Ventricular Dysfunction in Mitral Regurgitation Surgery

Who this might be right for
Severe Mitral RegurgitationPreserved Ventricular Ejection Fraction
University Hospital, Clermont-Ferrand 79
Post-approval studies (Phase 4)Not Yet RecruitingNCT07417215
What this trial is testing

The Effect of Sacubitril and Valsartan on Heart Function in Chronic Hemodialysis Patients With HFpEF

Who this might be right for
Heart Failure With Preserved Ejection Fraction (HFPEF)HemodialysisSacubitril/Valsartan
University Clinical Hospital Mostar 60
Not applicableWithdrawnNCT03160625
What this trial is testing

Evaluation of Rate Adaptive Pacing on Chronotropic Response in Preserved Ejection Fraction HF

Who this might be right for
Heart Failure With Preserved Ejection Fraction
Medtronic Cardiac Rhythm and Heart Failure
Large-scale testing (Phase 3)Looking for participantsNCT07288398
What this trial is testing

LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

Who this might be right for
Pulmonary Hypertension Associated With HFpEF
Tenax Therapeutics, Inc. 540
Not applicableNot Yet RecruitingNCT06510270
What this trial is testing

Dapagliflozin in Reducing Epicardial Adipose Tissue in Heart Failure with Preserved Ejection Fraction

Who this might be right for
Heart Failure with Preserved Ejection Fraction
Aswan University 70
Testing effectiveness (Phase 2)Study completedNCT00839228
What this trial is testing

Perhexiline Therapy in Heart Failure With Preserved Ejection Fraction Syndrome

Who this might be right for
Diastolic Heart Failure
University of Aberdeen 70
Large-scale testing (Phase 3)Active Not RecruitingNCT06683053
What this trial is testing

Evaluation of the Use of Empagliflozin in Patients with HF with PEF in a Cardiology Outpatient Department

Who this might be right for
Congestive Heart Failure (CHF)
Conrado Roberto Hoffmann Filho 90
Testing effectiveness (Phase 2)Study completedNCT06731738
What this trial is testing

Mangafodipir - an Intracellular Contrast Agent for Magnetic Resonance Imaging (MRI): Measuring Manganese Uptake Rate in Heart Failure Patients With Preserved Ejection Fraction (HFpEF) Patients.

Who this might be right for
Heart Failure With Preserved Ejection Fraction (HFPEF)
IC TARGETS AS 44
Not applicableNot Yet RecruitingNCT07414225
What this trial is testing

Safety and Efficacy of Transcatheter Edge-to-Edge Repair for Atrial Functional Mitral Regurgitation

Who this might be right for
Atrial Functional Mitral Regurgitation
Beijing Anzhen Hospital 400
Not applicableLooking for participantsNCT05752760
What this trial is testing

Pilot Study Lp299v Supplementation in Chronic Heart Failure

Who this might be right for
Heart FailureHeart Failure With Reduced Ejection FractionHeart Failure, Systolic+2 more
Medical College of Wisconsin 20
Testing effectiveness (Phase 2)Study completedNCT04945460
What this trial is testing

Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16)

Who this might be right for
Hypertension, Pulmonary
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA 164
Early research (Phase 1)Study completedNCT03843060
What this trial is testing

Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers

Who this might be right for
Heart Failure With Preserved Ejection Fraction (HFpEF)
AstraZeneca 14
Load More Results