Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Primary Generalized Tonic-clonic Seizures”

34 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 34 results

Large-scale testing (Phase 3)Study completedNCT03678753
What this trial is testing

Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in PGTC Seizures

Who this might be right for
Primary Generalized Epilepsy
SK Life Science, Inc. 169
Testing effectiveness (Phase 2)Study completedNCT01118962
What this trial is testing

Open-Label Extension Study to Assess the Safety and Seizure Frequency Associated With Lacosamide for Primary Generalized Tonic-Clonic Seizures in Subjects With Epilepsy

Who this might be right for
Epilepsy
UCB BIOSCIENCES, Inc. 39
Large-scale testing (Phase 3)Looking for participantsNCT06579573
What this trial is testing

ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures.

Who this might be right for
Epilepsy, Generalized
Ono Pharmaceutical Co. Ltd 15
Post-approval studies (Phase 4)Study completedNCT03288129
What this trial is testing

Study to Evaluate the Efficacy and Safety of Perampanel as Monotherapy or First Adjunctive Therapy in Subjects With Partial Onset Seizures With or Without Secondarily Generalized Seizures or With Primary Generalized Tonic-Clonic Seizures

Who this might be right for
Partial Onset SeizuresSecondarily Generalized SeizuresPrimary Generalized Tonic-Clonic Seizures
Eisai Inc. 54
Not applicableLooking for participantsNCT06657378
What this trial is testing

Evaluate the Safety of Fycompa Injection in Participants With Partial-Onset Seizures or Primary Generalized Tonic- Clonic Seizures

Who this might be right for
Partial-Onset SeizuresPrimary Generalized Tonic-clonic Seizures
Eisai Co., Ltd. 110
Not applicableStudy completedNCT02722590
What this trial is testing

Fycompa (Perampanel) in Korean Participants

Who this might be right for
Epilepsy
Eisai Korea Inc. 3,692
Large-scale testing (Phase 3)Study completedNCT00104416
What this trial is testing

Study Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Primary Generalized Tonic-Clonic Seizures (PGTC) Seizures

Who this might be right for
Epilepsy, Tonic-Clonic
GlaxoSmithKline 153
Large-scale testing (Phase 3)Active Not RecruitingNCT05147571
What this trial is testing

RNS System NAUTILUS Study

Who this might be right for
EpilepsyIdiopathic Generalized EpilepsyGeneralized Tonic Clonic Seizure
NeuroPace 100
Testing effectiveness (Phase 2)Looking for participantsNCT06908356
What this trial is testing

An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures

Who this might be right for
Focal Onset SeizurePrimary Generalized Epilepsy
Praxis Precision Medicines 50
Not applicableNo Longer AvailableNCT02307578
What this trial is testing

An Extended Access Program (EAP) for Perampanel

Who this might be right for
Primary Generalized Tonic-Clonic or Partial Onset SeizuresLennox Gastaut Syndrome
Eisai Inc.
Large-scale testing (Phase 3)Study completedNCT00236886
What this trial is testing

Prospective Pilot Study on Metabolism and Weight Changes in Topiramate-Treated Epilepsy Patients

Who this might be right for
EpilepsyEpilepsies, PartialEpilepsy, Generalized+1 more
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 49
Not applicableStudy completedNCT02736162
What this trial is testing

Study to Investigate Dosage, Efficacy, and Safety of Perampanel Given as Monotherapy in Patients With Epilepsy

Who this might be right for
EpilepsyPartial-Onset SeizuresPrimary Generalized Tonic-Clonic Seizures
Eisai Inc. 61
Large-scale testing (Phase 3)Ended earlyNCT00692003
What this trial is testing

Adjunctive Zonisamide in Primary Generalised Tonic Clonic Seizures

Who this might be right for
Epilepsy
Eisai Limited 21
Testing effectiveness (Phase 2)Study completedNCT03754582
What this trial is testing

Intravenous Perampanel in Japanese Participants With Epilepsy

Who this might be right for
EpilepsySeizures
Eisai Co., Ltd. 21
Large-scale testing (Phase 3)Study completedNCT01463306
What this trial is testing

A 12-Month Study To Evaluate The Safety And Tolerability Of Pregabalin As Add-On Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-Clonic Seizures

Who this might be right for
Epilepsy, Partial SeizuresEpilepsy, Primary Generalized Tonic-Clonic Seizures
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 605
Testing effectiveness (Phase 2)Looking for participantsNCT07130786
What this trial is testing

Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

Who this might be right for
SeizuresPrimary Motor CortexBrain Metastases From Non-small Cell Lung Cancer (NSCLC)+2 more
Ayal A. Aizer, MD 150
Large-scale testing (Phase 3)Enrolling By InvitationNCT03961568
What this trial is testing

Cenobamate Open-Label Extension Study for YKP3089C025

Who this might be right for
Primary Generalized Tonic Clonic Seizures in the Setting of Idiopathic Generalized Epilepsy
SK Life Science, Inc. 145
Not applicableStudy completedNCT03059329
What this trial is testing

Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adult Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures

Who this might be right for
Partial Seizures (With or Without Secondary Generalized Seizures)Primary Generalized Tonic-clonic Seizures
Eisai Co., Ltd. 3,809
Post-approval studies (Phase 4)Study completedNCT00043901
What this trial is testing

Treatment Of Primary Generalized Tonic-Clonic Seizures With An Investigational New Drug

Who this might be right for
Epilepsy, Tonic-Clonic
GlaxoSmithKline 141
Large-scale testing (Phase 3)Study completedNCT02849626
What this trial is testing

Perampanel as Adjunctive Therapy in Pediatrics With Partial Onset Seizures or Primary Generalized Tonic Clonic Seizures

Who this might be right for
Partial-Onset or Primary Generalized Tonic-Clonic Seizures
Eisai Inc. 180
Load More Results