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Results for “Primary Haemophagocytic Lymphohistiocytosis”

29 trials

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Showing 20 of 29 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02061800
What this trial is testing

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Who this might be right for
Chronic Myeloid Leukemia (CML)Acute Myelogenous Leukemia (AML)Myelodysplastic Syndrome (MDS)+3 more
Diane George 14
Testing effectiveness (Phase 2)Study completedNCT00176865
What this trial is testing

Stem Cell Transplant for Immunologic or Histiocytic Disorders

Who this might be right for
Hemophagocytic LymphohistiocytosisX-Linked Lymphoproliferative DisordersChediak-Higashi Syndrome+3 more
Masonic Cancer Center, University of Minnesota 19
Not applicableLooking for participantsNCT04528355
What this trial is testing

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+2 more
Paul Szabolcs 50
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Early research (Phase 1)Active Not RecruitingNCT00710892
What this trial is testing

CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene

Who this might be right for
Acute Lymphoblastic LeukemiaNon-Hodgkin's LymphomaMyelodysplastic Syndrome+1 more
Baylor College of Medicine 10
Testing effectiveness (Phase 2)Study completedNCT00919503
What this trial is testing

Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders

Who this might be right for
Non-Neoplastic Hematologic and Lymphocytic Disorder
Fred Hutchinson Cancer Center 98
Testing effectiveness (Phase 2)Study completedNCT01998633
What this trial is testing

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)

Who this might be right for
Hemophagocytic LymphohistiocytosisChronic Active Epstein-Barr Virus InfectionChronic Granulomatous Disease+3 more
Medical College of Wisconsin 47
Not applicableActive Not RecruitingNCT05236764
What this trial is testing

Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion

Who this might be right for
Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia in RemissionMyelodysplastic Syndromes+8 more
Baylor College of Medicine 3
Large-scale testing (Phase 3)Ended earlyNCT00176826
What this trial is testing

T-Cell Depletion and Stem Cell Transplant for Immune Deficiencies and Histiocytic Disorders

Who this might be right for
Hemophagocytic LymphohistiocytosisX-Linked Lymphoproliferative DisordersChediak-Higashi Syndrome+4 more
Masonic Cancer Center, University of Minnesota 22
Large-scale testing (Phase 3)Study completedNCT03312751
What this trial is testing

Study to Assess the Efficacy and Safety of Emapalumab in Primary Haemophagocytic Lymphohistiocytosis

Who this might be right for
Primary Hemophagocytic Lymphohistiocytosis
Swedish Orphan Biovitrum 35
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
Not applicableUnknownNCT00006056
What this trial is testing

Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders

Who this might be right for
Chediak-Higashi SyndromeGraft Versus Host DiseaseX-Linked Lymphoproliferative Syndrome+3 more
Fairview University Medical Center 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06736080
What this trial is testing

Safety and Efficacy of Gene Therapy of FHL Type 3 Caused by Mutations in the Human UNC13D Gene by Transplantation of a Single Dose of Autologous CD34+ Cells Transduced Ex Vivo with the UNC13D LV Vector Expressing the UNC13D CDNA

Who this might be right for
Familial Hemophagocytic Lymphohistiocytosis Type 3 (FHL 3)
Assistance Publique - Hôpitaux de Paris 5
Early research (Phase 1)Ended earlyNCT02231710
What this trial is testing

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

Who this might be right for
Primary Immune Deficiency DisordersHemophagocytic LymphohistiocytosisInherited Bone Marrow Failure Syndrome+2 more
Bellicum Pharmaceuticals 1
Not applicableActive Not RecruitingNCT01652092
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies

Who this might be right for
SCIDOmenn's SyndromeReticular Dysgenesis+11 more
Masonic Cancer Center, University of Minnesota 57
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05762640
What this trial is testing

Ruxolitinib as First Line Treatment in Primary Haemophagocytic Lymphohistiocytosis (R-HLH)

Who this might be right for
Haemophagocytic Lymphohistiocytosis
Assistance Publique - Hôpitaux de Paris 20
Testing effectiveness (Phase 2)Study completedNCT00368355
What this trial is testing

T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts

Who this might be right for
Acute Lymphoblastic LeukemiaNon Hodgkins LymphomaMyelodysplastic Syndrome+6 more
Baylor College of Medicine 46
Early research (Phase 1)Study completedNCT01917708
What this trial is testing

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Who this might be right for
Hurler SyndromeFanconi AnemiaGlanzmann Thrombasthenia+12 more
Emory University 10
Not applicableActive Not RecruitingNCT03827343
What this trial is testing

Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer

Who this might be right for
Macrophage Activation SyndromePrimary Hemophagocytic Lymphohistiocytosis
National Cancer Institute (NCI) 500
Not applicableActive Not RecruitingNCT06587191
What this trial is testing

Emapalumab Efficacy in Children With Primary Hemophagocytic Lymphohistiocytosis

Who this might be right for
Primary Hemophagocytic Lymphohistiocytosis
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 7
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