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Results for “Primary Haemophagocytic Lymphohistiocytosis”

29 trials

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Showing 20 of 29 results

Testing effectiveness (Phase 2)Study completedNCT00176865
What this trial is testing

Stem Cell Transplant for Immunologic or Histiocytic Disorders

Who this might be right for
Hemophagocytic LymphohistiocytosisX-Linked Lymphoproliferative DisordersChediak-Higashi Syndrome+3 more
Masonic Cancer Center, University of Minnesota 19
Early research (Phase 1)Active Not RecruitingNCT00710892
What this trial is testing

CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene

Who this might be right for
Acute Lymphoblastic LeukemiaNon-Hodgkin's LymphomaMyelodysplastic Syndrome+1 more
Baylor College of Medicine 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT01821781
What this trial is testing

Immune Disorder HSCT Protocol

Who this might be right for
Immune Deficiency DisordersSevere Combined ImmunodeficiencyChronic Granulomatous Disease+11 more
Washington University School of Medicine 20
Not applicableActive Not RecruitingNCT03827343
What this trial is testing

Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer

Who this might be right for
Macrophage Activation SyndromePrimary Hemophagocytic Lymphohistiocytosis
National Cancer Institute (NCI) 500
Not applicableEnded earlyNCT00006054
What this trial is testing

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies

Who this might be right for
Immunologic Deficiency SyndromesChediak-Higashi SyndromeCommon Variable Immunodeficiency+11 more
Fairview University Medical Center
Early research (Phase 1)Study completedNCT01917708
What this trial is testing

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Who this might be right for
Hurler SyndromeFanconi AnemiaGlanzmann Thrombasthenia+12 more
Emory University 10
Testing effectiveness (Phase 2)Study completedNCT00368355
What this trial is testing

T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts

Who this might be right for
Acute Lymphoblastic LeukemiaNon Hodgkins LymphomaMyelodysplastic Syndrome+6 more
Baylor College of Medicine 46
Not applicableActive Not RecruitingNCT01652092
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies

Who this might be right for
SCIDOmenn's SyndromeReticular Dysgenesis+11 more
Masonic Cancer Center, University of Minnesota 57
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06736080
What this trial is testing

Safety and Efficacy of Gene Therapy of FHL Type 3 Caused by Mutations in the Human UNC13D Gene by Transplantation of a Single Dose of Autologous CD34+ Cells Transduced Ex Vivo with the UNC13D LV Vector Expressing the UNC13D CDNA

Who this might be right for
Familial Hemophagocytic Lymphohistiocytosis Type 3 (FHL 3)
Assistance Publique - Hôpitaux de Paris 5
Testing effectiveness (Phase 2)Study completedNCT01998633
What this trial is testing

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)

Who this might be right for
Hemophagocytic LymphohistiocytosisChronic Active Epstein-Barr Virus InfectionChronic Granulomatous Disease+3 more
Medical College of Wisconsin 47
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05762640
What this trial is testing

Ruxolitinib as First Line Treatment in Primary Haemophagocytic Lymphohistiocytosis (R-HLH)

Who this might be right for
Haemophagocytic Lymphohistiocytosis
Assistance Publique - Hôpitaux de Paris 20
Not applicableLooking for participantsNCT04902807
What this trial is testing

Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation

Who this might be right for
Autoimmune Lymphoproliferative SyndromeAutoimmune CytopeniaAutoimmune Diseases+17 more
Institut National de la Santé Et de la Recherche Médicale, France 500
Not applicableLooking for participantsNCT04528355
What this trial is testing

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+2 more
Paul Szabolcs 50
Early research (Phase 1)Ended earlyNCT02231710
What this trial is testing

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

Who this might be right for
Primary Immune Deficiency DisordersHemophagocytic LymphohistiocytosisInherited Bone Marrow Failure Syndrome+2 more
Bellicum Pharmaceuticals 1
Post-approval studies (Phase 4)Study completedNCT05744063
What this trial is testing

A Post-authorization Study to Describe the Safety and Efficacy of Emapalumab for the Treatment of pHLH in Treatment Experienced Chinese Patients

Who this might be right for
Primary Hemophagocytic Lymphohistiocytosis
Swedish Orphan Biovitrum 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT02061800
What this trial is testing

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Who this might be right for
Chronic Myeloid Leukemia (CML)Acute Myelogenous Leukemia (AML)Myelodysplastic Syndrome (MDS)+3 more
Diane George 14
Early research (Phase 1)Active Not RecruitingNCT01494103
What this trial is testing

Administration of Donor T Cells With the Caspase-9 Suicide Gene

Who this might be right for
Acute Lymphoblastic LeukemiaMyelodysplastic SyndromeAcute Myeloid Leukemia+7 more
Baylor College of Medicine 15
Testing effectiveness (Phase 2)Study completedNCT03513328
What this trial is testing

Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation

Who this might be right for
Bone Marrow Failure SyndromeThalassemiaSickle Cell Disease+13 more
University of Florida 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT01966367
What this trial is testing

CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation

Who this might be right for
Bone Marrow Failure SyndromeSevere Aplastic AnemiaSevere Congenital Neutropenia+13 more
Diane George 37
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