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Results for “Primary Hyperoxaluria Type 1”

54 trials

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Showing 20 of 54 results

Early research (Phase 1)Ended earlyNCT02795325
What this trial is testing

DCR-PH1 in Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 41
Not applicableLooking for participantsNCT02026388
What this trial is testing

Rare Kidney Stone Consortium Biobank

Who this might be right for
Primary HyperoxaluriaDent DiseaseAPRT Deficiency+1 more
Mayo Clinic 2,000
Not applicableUnknownNCT05843851
What this trial is testing

Genetic Newborn Screening for Cystinosis and Primary Hyperoxaluria

Who this might be right for
CystinosisPrimary Hyperoxaluria
Cystinose Stiftung 200,000
Early research (Phase 1)Study completedNCT04555486
What this trial is testing

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients

Who this might be right for
Primary Hyperoxaluria Type 3
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 6
Not applicableWithdrawnNCT00875823
What this trial is testing

International Registry for Primary Hyperoxaluria

Who this might be right for
Primary HyperoxaluriaNephrocalcinosisKidney Stones
Mayo Clinic
Not applicableUnknownNCT05107830
What this trial is testing

Phenotyping of Primary Hyperoxaluria

Who this might be right for
Primary Hyperoxaluria
University Hospital, Strasbourg, France 186
Large-scale testing (Phase 3)Study completedNCT01037231
What this trial is testing

Phase 2/3 Oxabact Study

Who this might be right for
Primary Hyperoxaluria
OxThera 36
Testing effectiveness (Phase 2)Study completedNCT03350451
What this trial is testing

An Extension Study of an Investigational Drug, Lumasiran (ALN-GO1), in Participants With Primary Hyperoxaluria Type 1

Who this might be right for
PH1Primary HyperoxaluriaRNAi Therapeutic+2 more
Alnylam Pharmaceuticals 20
Large-scale testing (Phase 3)Ended earlyNCT03938272
What this trial is testing

An Extension Study to Evaluate the Long-term Efficacy and Safety of Oxabact in Patients With Primary Hyperoxaluria

Who this might be right for
Hyperoxaluria, Primary
OxThera 22
Large-scale testing (Phase 3)WithdrawnNCT00280215
What this trial is testing

Renal Protective Effect of ACEI and ARB in Primary Hyperoxaluria

Who this might be right for
Hyperoxaluria
Mayo Clinic
Testing effectiveness (Phase 2)Looking for participantsNCT04580420
What this trial is testing

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

Who this might be right for
Primary Hyperoxaluria Type 1End Stage Renal Disease
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 28
Testing effectiveness (Phase 2)Study completedNCT00283387
What this trial is testing

Efficacy of Betaine for Reduction of Urine Oxalate in Patients With Type 1 Primary Hyperoxaluria

Who this might be right for
Hyperoxaluria
Mayo Clinic 15
Testing effectiveness (Phase 2)Looking for participantsNCT06839235
What this trial is testing

Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Arbor Biotechnologies 23
Testing effectiveness (Phase 2)Study completedNCT02012985
What this trial is testing

Study to Evaluate the Efficacy and Safety of Oxabact (OC5) in Patients With Primary Hyperoxaluria

Who this might be right for
Primary Hyperoxaluria
OxThera 28
Testing effectiveness (Phase 2)Study completedNCT02706886
What this trial is testing

Study of Lumasiran in Healthy Adults and Patients With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Alnylam Pharmaceuticals 52
Testing effectiveness (Phase 2)Looking for participantsNCT07587021
What this trial is testing

Study of YOLT-203 in Children and Adults With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1PH1
YolTech Therapeutics Co., Ltd 36
Testing effectiveness (Phase 2)Study completedNCT03847909
What this trial is testing

Evaluate DCR-PHXC in Children and Adults With Primary Hyperoxaluria Type 1 and Primary Hyperoxaluria Type 2

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)Primary Hyperoxaluria Type 2 (PH2)Kidney Diseases+2 more
Novo Nordisk A/S 35
Not applicableActive Not RecruitingNCT04982393
What this trial is testing

BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1
Alnylam Pharmaceuticals 207
Not applicableLooking for participantsNCT03305835
What this trial is testing

Monogenic Kidney Stone - Genetic Testing

Who this might be right for
Rare Kidney Stone Diseases
Mayo Clinic 6,000
Early research (Phase 1)Study completedNCT03392896
What this trial is testing

Study of DCR-PHXC-101 in Normal Healthy Volunteers and Patients With Primary Hyperoxaluria

Who this might be right for
Primary Hyperoxaluria
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 43
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