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Results for “Primary Hyperoxaluria Type 1 (PH1)”

26 trials

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Showing 20 of 26 results

Large-scale testing (Phase 3)Study completedNCT03681184
What this trial is testing

Evaluate Lumasiran in Children and Adults With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Alnylam Pharmaceuticals 39
Testing effectiveness (Phase 2)Study completedNCT02706886
What this trial is testing

Study of Lumasiran in Healthy Adults and Patients With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Alnylam Pharmaceuticals 52
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableLooking for participantsNCT00588562
What this trial is testing

Rare Kidney Stone Consortium Patient Registry

Who this might be right for
Primary HyperoxaluriaDent DiseaseCystinuria+1 more
Mayo Clinic 730
Very early researchLooking for participantsNCT06511349
What this trial is testing

Clinical Exploration Study of YOLT-203 in the Treatment of Type 1 Primary Hyperoxaluria (PH1)

Who this might be right for
Type 1 Primary Hyperoxaluria
RenJi Hospital 21
Large-scale testing (Phase 3)Not Yet RecruitingNCT06465472
What this trial is testing

Evaluation of the Efficacy and Safety of Stiripentol in Patients 6 Years and Older With Primary Hyperoxaluria Type 1, 2 or 3

Who this might be right for
Primary Hyperoxaluria Type 1Primary Hyperoxaluria Type 2Primary Hyperoxaluria Type 3
Biocodex 42
Testing effectiveness (Phase 2)Study completedNCT03847909
What this trial is testing

Evaluate DCR-PHXC in Children and Adults With Primary Hyperoxaluria Type 1 and Primary Hyperoxaluria Type 2

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)Primary Hyperoxaluria Type 2 (PH2)Kidney Diseases+2 more
Novo Nordisk A/S 35
Large-scale testing (Phase 3)Active Not RecruitingNCT04042402
What this trial is testing

Long Term Extension Study in Patients With Primary Hyperoxaluria

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)Primary Hyperoxaluria Type 2 (PH2)Kidney Diseases+3 more
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 75
Not applicableLooking for participantsNCT03305835
What this trial is testing

Monogenic Kidney Stone - Genetic Testing

Who this might be right for
Rare Kidney Stone Diseases
Mayo Clinic 6,000
Not applicableStudy completedNCT06283082
What this trial is testing

Oxalate Excretion Profile in Patients With a Heterozygous Mutation of the AGXT (Alanine-glyoxylate Aminotransferase) Gene

Who this might be right for
Hyperoxaluria (Disorder)
Hospices Civils de Lyon 25
Testing effectiveness (Phase 2)Study completedNCT05001269
What this trial is testing

Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function

Who this might be right for
Primary HyperoxaluriaPrimary Hyperoxaluria Type 1Primary Hyperoxaluria Type 2+1 more
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 27
Not applicableLooking for participantsNCT02026388
What this trial is testing

Rare Kidney Stone Consortium Biobank

Who this might be right for
Primary HyperoxaluriaDent DiseaseAPRT Deficiency+1 more
Mayo Clinic 2,000
Testing effectiveness (Phase 2)Looking for participantsNCT04580420
What this trial is testing

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

Who this might be right for
Primary Hyperoxaluria Type 1End Stage Renal Disease
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 28
Testing effectiveness (Phase 2)Looking for participantsNCT06839235
What this trial is testing

Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Arbor Biotechnologies 23
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07587021
What this trial is testing

Study of YOLT-203 in Children and Adults With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1PH1
YolTech Therapeutics Co., Ltd 36
Not applicableStudy completedNCT03067142
What this trial is testing

Proteomics of Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1
Ann & Robert H Lurie Children's Hospital of Chicago 93
Not applicableNo Longer AvailableNCT05993416
What this trial is testing

Treatment of Primary Hyperoxaluria Type 1 With Nedosiran

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Large-scale testing (Phase 3)Study completedNCT04152200
What this trial is testing

Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1Primary Hyperoxaluria
Alnylam Pharmaceuticals 21
Not applicableActive Not RecruitingNCT04982393
What this trial is testing

BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1
Alnylam Pharmaceuticals 207
Large-scale testing (Phase 3)Study completedNCT03905694
What this trial is testing

Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1

Who this might be right for
Primary HyperoxaluriaPrimary Hyperoxaluria Type 1 (PH1)
Alnylam Pharmaceuticals 18
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