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Results for “Primary Hyperoxaluria Type 1 (PH1)”

25 trials

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Showing 20 of 25 results

Testing effectiveness (Phase 2)Looking for participantsNCT04580420
What this trial is testing

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

Who this might be right for
Primary Hyperoxaluria Type 1End Stage Renal Disease
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 28
Early research (Phase 1)Ended earlyNCT02795325
What this trial is testing

DCR-PH1 in Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 41
Not applicableLooking for participantsNCT02026388
What this trial is testing

Rare Kidney Stone Consortium Biobank

Who this might be right for
Primary HyperoxaluriaDent DiseaseAPRT Deficiency+1 more
Mayo Clinic 2,000
Large-scale testing (Phase 3)Study completedNCT04152200
What this trial is testing

Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1Primary Hyperoxaluria
Alnylam Pharmaceuticals 21
Not applicableLooking for participantsNCT06283082
What this trial is testing

Oxalate Excretion Profile in Patients with a Heterozygous Mutation of the AGXT (alanine-glyoxylate Aminotransferase) Gene

Who this might be right for
Hyperoxaluria (Disorder)
Hospices Civils de Lyon 25
Not applicableNo Longer AvailableNCT05993416
What this trial is testing

Treatment of Primary Hyperoxaluria Type 1 With Nedosiran

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Not applicableStudy completedNCT02830009
What this trial is testing

IDENTIFICATION OF A MULTI-ANALYTE PROFILE FOR PRIMARY HYPEROXALURIA AND COMPARISON WITH HEALTHY SIBLINGS AND IDIOPATHIC HYPERCALCIURIA

Who this might be right for
Primary Hyperoxaluria Type 1Idiopathic Hypercalciuria
Hospices Civils de Lyon 5
Very early researchActive Not RecruitingNCT06892301
What this trial is testing

Clinical Exploration Study of YOLT-203 in the Treatment of Type 1 Primary Hyperoxaluria (PH1)

Who this might be right for
Type 1 Primary Hyperoxaluria
Guangzhou Women and Children's Medical Center 2
Testing effectiveness (Phase 2)Study completedNCT05001269
What this trial is testing

Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function

Who this might be right for
Primary HyperoxaluriaPrimary Hyperoxaluria Type 1Primary Hyperoxaluria Type 2+1 more
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 27
Not applicableLooking for participantsNCT03305835
What this trial is testing

Monogenic Kidney Stone - Genetic Testing

Who this might be right for
Rare Kidney Stone Diseases
Mayo Clinic 6,000
Testing effectiveness (Phase 2)Looking for participantsNCT06839235
What this trial is testing

Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Arbor Biotechnologies 23
Very early researchLooking for participantsNCT06511349
What this trial is testing

Clinical Exploration Study of YOLT-203 in the Treatment of Type 1 Primary Hyperoxaluria (PH1)

Who this might be right for
Type 1 Primary Hyperoxaluria
RenJi Hospital 21
Large-scale testing (Phase 3)Active Not RecruitingNCT04042402
What this trial is testing

Long Term Extension Study in Patients With Primary Hyperoxaluria

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)Primary Hyperoxaluria Type 2 (PH2)Kidney Diseases+3 more
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 75
Not applicableActive Not RecruitingNCT04982393
What this trial is testing

BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1
Alnylam Pharmaceuticals 207
Testing effectiveness (Phase 2)Study completedNCT03350451
What this trial is testing

An Extension Study of an Investigational Drug, Lumasiran (ALN-GO1), in Participants With Primary Hyperoxaluria Type 1

Who this might be right for
PH1Primary HyperoxaluriaRNAi Therapeutic+2 more
Alnylam Pharmaceuticals 20
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Testing effectiveness (Phase 2)Study completedNCT02706886
What this trial is testing

Study of Lumasiran in Healthy Adults and Patients With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Alnylam Pharmaceuticals 52
Not applicableLooking for participantsNCT06225882
What this trial is testing

Retrospective and Prospective Follow-up of Patients With Primary Hyperoxaluria Type 1 Treated With Lumasiran in France.

Who this might be right for
Patients With PH1 Treated With Lumasiran in France
Hospices Civils de Lyon 100
Not applicableLooking for participantsNCT00588562
What this trial is testing

Rare Kidney Stone Consortium Patient Registry

Who this might be right for
Primary HyperoxaluriaDent DiseaseCystinuria+1 more
Mayo Clinic 730
Large-scale testing (Phase 3)Study completedNCT03681184
What this trial is testing

Evaluate Lumasiran in Children and Adults With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Alnylam Pharmaceuticals 39
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