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Results for “Primary Hyperoxaluria Type 1 (PH1)”

27 trials

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Showing 20 of 27 results

Not applicableLooking for participantsNCT06225882
What this trial is testing

Retrospective and Prospective Follow-up of Patients With Primary Hyperoxaluria Type 1 Treated With Lumasiran in France.

Who this might be right for
Patients With PH1 Treated With Lumasiran in France
Hospices Civils de Lyon 100
Testing effectiveness (Phase 2)Study completedNCT03350451
What this trial is testing

An Extension Study of an Investigational Drug, Lumasiran (ALN-GO1), in Participants With Primary Hyperoxaluria Type 1

Who this might be right for
PH1Primary HyperoxaluriaRNAi Therapeutic+2 more
Alnylam Pharmaceuticals 20
Early research (Phase 1)Ended earlyNCT02795325
What this trial is testing

DCR-PH1 in Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 41
Large-scale testing (Phase 3)Study completedNCT03905694
What this trial is testing

Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1

Who this might be right for
Primary HyperoxaluriaPrimary Hyperoxaluria Type 1 (PH1)
Alnylam Pharmaceuticals 18
Large-scale testing (Phase 3)Study completedNCT03681184
What this trial is testing

Evaluate Lumasiran in Children and Adults With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Alnylam Pharmaceuticals 39
Testing effectiveness (Phase 2)Study completedNCT02706886
What this trial is testing

Study of Lumasiran in Healthy Adults and Patients With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Alnylam Pharmaceuticals 52
Not applicableLooking for participantsNCT02026388
What this trial is testing

Rare Kidney Stone Consortium Biobank

Who this might be right for
Primary HyperoxaluriaDent DiseaseAPRT Deficiency+1 more
Mayo Clinic 2,000
Early research (Phase 1)Looking for participantsNCT07776626
What this trial is testing

Phase I Exploratory Study of YOLT-203 in Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1PH1
YolTech Therapeutics Co., Ltd 9
Not applicableLooking for participantsNCT00588562
What this trial is testing

Rare Kidney Stone Consortium Patient Registry

Who this might be right for
Primary HyperoxaluriaDent DiseaseCystinuria+1 more
Mayo Clinic 730
Not applicableStudy completedNCT06283082
What this trial is testing

Oxalate Excretion Profile in Patients With a Heterozygous Mutation of the AGXT (Alanine-glyoxylate Aminotransferase) Gene

Who this might be right for
Hyperoxaluria (Disorder)
Hospices Civils de Lyon 25
Testing effectiveness (Phase 2)Looking for participantsNCT07587021
What this trial is testing

Study of YOLT-203 in Children and Adults With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1PH1
YolTech Therapeutics Co., Ltd 36
Not applicableNo Longer AvailableNCT05993416
What this trial is testing

Treatment of Primary Hyperoxaluria Type 1 With Nedosiran

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Not applicableStudy completedNCT02830009
What this trial is testing

IDENTIFICATION OF A MULTI-ANALYTE PROFILE FOR PRIMARY HYPEROXALURIA AND COMPARISON WITH HEALTHY SIBLINGS AND IDIOPATHIC HYPERCALCIURIA

Who this might be right for
Primary Hyperoxaluria Type 1Idiopathic Hypercalciuria
Hospices Civils de Lyon 5
Large-scale testing (Phase 3)Not Yet RecruitingNCT06465472
What this trial is testing

Evaluation of the Efficacy and Safety of Stiripentol in Patients 6 Years and Older With Primary Hyperoxaluria Type 1, 2 or 3

Who this might be right for
Primary Hyperoxaluria Type 1Primary Hyperoxaluria Type 2Primary Hyperoxaluria Type 3
Biocodex 42
Not applicableApproved For MarketingNCT04125472
What this trial is testing

Expanded Access Protocol to Provide Lumasiran to Patients With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria
Alnylam Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT04152200
What this trial is testing

Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1Primary Hyperoxaluria
Alnylam Pharmaceuticals 21
Testing effectiveness (Phase 2)Study completedNCT05001269
What this trial is testing

Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function

Who this might be right for
Primary HyperoxaluriaPrimary Hyperoxaluria Type 1Primary Hyperoxaluria Type 2+1 more
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 27
Not applicableActive Not RecruitingNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Very early researchLooking for participantsNCT06511349
What this trial is testing

Clinical Exploration Study of YOLT-203 in the Treatment of Type 1 Primary Hyperoxaluria (PH1)

Who this might be right for
Type 1 Primary Hyperoxaluria
RenJi Hospital 21
Testing effectiveness (Phase 2)Study completedNCT03847909
What this trial is testing

Evaluate DCR-PHXC in Children and Adults With Primary Hyperoxaluria Type 1 and Primary Hyperoxaluria Type 2

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)Primary Hyperoxaluria Type 2 (PH2)Kidney Diseases+2 more
Novo Nordisk A/S 35
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