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Results for “Primary Hyperoxaluria Type I”

50 trials

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Showing 20 of 50 results

Testing effectiveness (Phase 2)Study completedNCT03819647
What this trial is testing

Evaluation of the Efficacy of Stiripentol (Diacomit) as Monotherapy for the Treatment of Primary Hyperoxaluria

Who this might be right for
Primary Hyperoxaluria
Biocodex 15
Large-scale testing (Phase 3)Not Yet RecruitingNCT06465472
What this trial is testing

Evaluation of the Efficacy and Safety of Stiripentol in Patients 6 Years and Older With Primary Hyperoxaluria Type 1, 2 or 3

Who this might be right for
Primary Hyperoxaluria Type 1Primary Hyperoxaluria Type 2Primary Hyperoxaluria Type 3
Biocodex 42
Not applicableUnknownNCT05107830
What this trial is testing

Phenotyping of Primary Hyperoxaluria

Who this might be right for
Primary Hyperoxaluria
University Hospital, Strasbourg, France 186
Large-scale testing (Phase 3)Study completedNCT03905694
What this trial is testing

Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1

Who this might be right for
Primary HyperoxaluriaPrimary Hyperoxaluria Type 1 (PH1)
Alnylam Pharmaceuticals 18
Large-scale testing (Phase 3)Ended earlyNCT03938272
What this trial is testing

An Extension Study to Evaluate the Long-term Efficacy and Safety of Oxabact in Patients With Primary Hyperoxaluria

Who this might be right for
Hyperoxaluria, Primary
OxThera 22
Not applicableLooking for participantsNCT02780297
What this trial is testing

Prospective Research Rare Kidney Stones (ProRKS)

Who this might be right for
HyperoxaluriaCystinuriaDent Disease+2 more
Mayo Clinic 220
Early research (Phase 1)Study completedNCT03392896
What this trial is testing

Study of DCR-PHXC-101 in Normal Healthy Volunteers and Patients With Primary Hyperoxaluria

Who this might be right for
Primary Hyperoxaluria
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 43
Not applicableStudy completedNCT03067142
What this trial is testing

Proteomics of Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1
Ann & Robert H Lurie Children's Hospital of Chicago 93
Testing effectiveness (Phase 2)Study completedNCT03847909
What this trial is testing

Evaluate DCR-PHXC in Children and Adults With Primary Hyperoxaluria Type 1 and Primary Hyperoxaluria Type 2

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)Primary Hyperoxaluria Type 2 (PH2)Kidney Diseases+2 more
Novo Nordisk A/S 35
Large-scale testing (Phase 3)Study completedNCT00638703
What this trial is testing

Study to Evaluate the Efficacy and Safety of OxabactTM on Reduction of Urinary Oxalate in Primary Hyperoxaluria Patients

Who this might be right for
Primary Hyperoxaluria
OxThera 43
Not applicableApproved For MarketingNCT04125472
What this trial is testing

Expanded Access Protocol to Provide Lumasiran to Patients With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria
Alnylam Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT02706886
What this trial is testing

Study of Lumasiran in Healthy Adults and Patients With Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Alnylam Pharmaceuticals 52
Testing effectiveness (Phase 2)Study completedNCT03391804
What this trial is testing

Study of ALLN-177 in Patients Aged 12 Years or Older With Enteric or Primary Hyperoxaluria and Hyperoxalemia

Who this might be right for
Enteric HyperoxaluriaPrimary HyperoxaluriaHyperoxalemia
Allena Pharmaceuticals 15
Not applicableLooking for participantsNCT06065852
What this trial is testing

National Registry of Rare Kidney Diseases

Who this might be right for
Adenine Phosphoribosyltransferase DeficiencyAH AmyloidosisAHL Amyloidosis+81 more
UK Kidney Association 35,000
Not applicableNo Longer AvailableNCT05993416
What this trial is testing

Treatment of Primary Hyperoxaluria Type 1 With Nedosiran

Who this might be right for
Primary Hyperoxaluria Type 1 (PH1)
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Large-scale testing (Phase 3)Study completedNCT04152200
What this trial is testing

Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1

Who this might be right for
Primary Hyperoxaluria Type 1Primary Hyperoxaluria
Alnylam Pharmaceuticals 21
Not applicableActive Not RecruitingNCT04982393
What this trial is testing

BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1
Alnylam Pharmaceuticals 207
Early research (Phase 1)Study completedNCT04555486
What this trial is testing

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients

Who this might be right for
Primary Hyperoxaluria Type 3
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 6
Not applicableStudy completedNCT02340689
What this trial is testing

Primary Hyperoxaluria Mutation Genotyping/Phenotyping

Who this might be right for
Primary Hyperoxaluria
Mayo Clinic 1,235
Testing effectiveness (Phase 2)Study completedNCT02038543
What this trial is testing

Hydroxyproline Influence on Oxalate Metabolism

Who this might be right for
Hyperoxaluria
Mayo Clinic 22
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