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Results for “Primary Myelofibrosis (MF)”

141 trials

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Showing 20 of 141 results

Testing effectiveness (Phase 2)WithdrawnNCT04629651
What this trial is testing

Captopril Use on the Degree of Marrow Fibrosis in Bone Marrow Fibrosis/Myeloproliferative Neoplasms

Who this might be right for
Bone Marrow FibrosisMyeloproliferative Neoplasm
Case Comprehensive Cancer Center
Early research (Phase 1)Study completedNCT01433445
What this trial is testing

Panobinostat and Ruxolitinib in Primary Myelofibrosis, Post-polycythemia Vera-myelofibrosis or Post-essential Thrombocythemia-myelofibrosis

Who this might be right for
Idiopathic MyelofibrosisPost Essential Thrombocythemia MyelofibrosisPost Polycythemia-Vera Myelofibrosis
Novartis Pharmaceuticals 61
Testing effectiveness (Phase 2)Study completedNCT00946270
What this trial is testing

Pomalidomide for Myelofibrosis Patients

Who this might be right for
Polycythemia VeraThrombocythemia
M.D. Anderson Cancer Center 70
Early research (Phase 1)Study completedNCT00910728
What this trial is testing

Study to Assess the Safety of AZD1480 in Patients With Myeloproliferative Diseases

Who this might be right for
Primary Myelofibrosis (PMF)Post-Polycythaemia VeraEssential Thrombocythaemia Myelofibrosis
AstraZeneca 65
Post-approval studies (Phase 4)Study completedNCT01558739
What this trial is testing

Exploratory Phase II Study of INC424 Patients With Primary Myelofibrosis (PMF) or Post Polycythaemia Myelofibrosis (PPV MF) or Post Essential Thrombocythaemia Myelofibrosis (PET-MF)

Who this might be right for
Primary Myelofibrosis (PMF)Post Polycythaemia Myelofibrosis (PPV MF)Post Essential Thrombocythaemia Myelofibrosis (PET-MF)
Novartis Pharmaceuticals 48
Large-scale testing (Phase 3)Study completedNCT01428635
What this trial is testing

Eltrombopag Olamine in Treating Thrombocytopenia in Patients With Chronic Myeloid Leukemia or Myelofibrosis Receiving Tyrosine Kinase Therapy

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveChronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive+2 more
M.D. Anderson Cancer Center 21
Not applicableStudy completedNCT02953704
What this trial is testing

Myelofibrosis and Essential Thrombocythemia Observational Study (MOST)

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 1,469
Early research (Phase 1)Active Not RecruitingNCT04041050
What this trial is testing

A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm

Who this might be right for
Myeloproliferative Neoplasm
AbbVie 85
Early research (Phase 1)Active Not RecruitingNCT05233618
What this trial is testing

Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MDS, MF and CMML (HSCT 002)

Who this might be right for
MyelofibrosisChronic Myelomonocytic LeukemiaAcute Myeloid Leukemia
Karen Ballen, MD 44
Testing effectiveness (Phase 2)Study completedNCT01348490
What this trial is testing

Ruxolitinib (INCB018424) in Participants With Primary Myelofibrosis (PMF), Post Essential Thrombocythemia-myelofibrosis and Post Polycythemia Vera-myelofibrosis (PPV-MF)

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 66
Testing effectiveness (Phase 2)Looking for participantsNCT07394153
What this trial is testing

Pacritinib For Bone Marrow Fibrosis In Patients With Myelofibrosis Who Have Thrombocytopenia

Who this might be right for
Myelofibrosis，MF
Grupo Español de Enfermedades Mieloproliferativas Crónicas PH Negativas 30
Large-scale testing (Phase 3)Study completedNCT01969838
What this trial is testing

Momelotinib Versus Ruxolitinib in Subjects With Myelofibrosis

Who this might be right for
Primary MyelofibrosisPost-Polycythemia Vera MyelofibrosisPost-Essential Thrombocythemia Myelofibrosis
Sierra Oncology LLC - a GSK company 432
Post-approval studies (Phase 4)Not Yet RecruitingNCT07498205
What this trial is testing

Comparing Momelotinib and Ruxolitinib in People With Untreated Myelofibrosis and Low Blood Cell Counts

Who this might be right for
MyelofibrosisMyelofibrosis (MF)
SWOG Cancer Research Network 268
Not applicableUnknownNCT05883904
What this trial is testing

Real World Evidence of Fedratinib Effectiveness in MF

Who this might be right for
Primary MyelofibrosisPost-polycythemia Vera MyelofibrosisPost-essential Thrombocythemia Myelofibrosis
Gruppo Italiano Malattie EMatologiche dell'Adulto 93
Testing effectiveness (Phase 2)UnknownNCT04640532
What this trial is testing

KRT-232 in Combination With TL-895 for the Treatment of R/R MF and KRT-232 for the Treatment of JAKi Intolerant MF

Who this might be right for
MyelofibrosisPost-PV MFPost-ET Myelofibrosis+1 more
Kartos Therapeutics, Inc. 116
Testing effectiveness (Phase 2)UnknownNCT04878003
What this trial is testing

Study of KRT-232 or TL-895 in Janus Associated Kinase Inhibitor Treatment-Naïve Myelofibrosis

Who this might be right for
Primary Myelofibrosis (PMF)Post-Polycythemia Vera Myelofibrosis (Post-PV-MF)Post-Essential Thrombocythemia Myelofibrosis (Post-ET-MF)
Kartos Therapeutics, Inc. 52
Testing effectiveness (Phase 2)Looking for participantsNCT05835466
What this trial is testing

Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)

Who this might be right for
Myelofibrosis (PMF)Post Essential Thrombocythemia Myelofibrosis (ET-MF)Post Polycythemia Vera Related Myelofibrosis (PV-MF)
Icahn School of Medicine at Mount Sinai 10
Not applicableLooking for participantsNCT06674382
What this trial is testing

Haplo-HSCT for Myelofibrosis

Who this might be right for
Myelofibrosis
Peking University People's Hospital 39
Testing effectiveness (Phase 2)Looking for participantsNCT06770842
What this trial is testing

Ropeginterferon Alfa 2b Plus Ruxolitinib for Myelofibrosis

Who this might be right for
Primary Myelofibrosis (PMF)Post Polycythemia Myelofibrosis (PPV MF)Post Essential Thrombocythaemia Myelofibrosis (PET-MF)
The University of Hong Kong 20
Testing effectiveness (Phase 2)Study completedNCT02426086
What this trial is testing

Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or High-Risk Myelofibrosis (MF) Previously Treated With Janus Kinase (JAK) Inhibitor

Who this might be right for
Myelofibrosis
Geron Corporation 107
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