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Results for “Primary Progressive Multiple Sclerosis (PPMS)”

30 trials

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Showing 20 of 30 results

Large-scale testing (Phase 3)Study completedNCT00087529
What this trial is testing

Evaluate the Safety and Efficacy of Rituximab in Adults With Primary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Genentech, Inc. 439
Large-scale testing (Phase 3)Study completedNCT04458051
What this trial is testing

Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)

Who this might be right for
Primary Progressive Multiple Sclerosis
Sanofi 767
Not applicableLooking for participantsNCT05177523
What this trial is testing

Imaging the Interplay Between Axonal Damage and Repair in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis (MS)Relapsing-remitting Multiple Sclerosis (RRMS)Secondary-progressive Multiple Sclerosis (SPMS)+1 more
University Hospital, Basel, Switzerland 300
Early research (Phase 1)Study completedNCT04943289
What this trial is testing

Intrathecal Administration of DUOC-01 in Adults With Primary Progressive Multiple Sclerosis

Who this might be right for
Primary Progressive Multiple Sclerosis
Joanne Kurtzberg, MD 20
Not applicableStudy completedNCT05974839
What this trial is testing

Effect of Ocrelizumab on Cortical Lesion Accumulation in Patients With PPMS (ORATORIO-Cortical)

Who this might be right for
Primary Progressive Multiple Sclerosis
State University of New York at Buffalo 732
Testing effectiveness (Phase 2)Looking for participantsNCT07477639
What this trial is testing

Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis

Who this might be right for
Primary Progressive Multiple SclerosisSecondary Progressive Multiple Sclerosis (SPMS)Multiple Sclerosis+2 more
Tr1X, Inc. 39
Large-scale testing (Phase 3)UnknownNCT02220244
What this trial is testing

Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
MedDay Pharmaceuticals SA 105
Not applicableStudy completedNCT01080014
What this trial is testing

Correlation Between Multiple Sclerosis Functional Composite (MSFC) and Expanded Disability Status Scale (EDSS) in Patients With Multiple Sclerosis (MS) in Argentina

Who this might be right for
Multiple Sclerosis
Merck KGaA, Darmstadt, Germany 252
Not applicableStudy completedNCT03455582
What this trial is testing

Cognition Evolution and MRI Markers in PPMS Patients on 2 Years

Who this might be right for
Multiple Sclerosis, Primary Progressive
University Hospital, Bordeaux 66
Testing effectiveness (Phase 2)Study completedNCT02284568
What this trial is testing

Clinical Study in Subjects With Primary Progressive Multiple Sclerosis to Assess the Efficacy, Safety and Tolerability of Two Oral Doses of Laquinimod Either of 0.6 mg/Day or 1.5mg/Day (Experimental Drug) as Compared to Placebo

Who this might be right for
Primary Progressive Multiple Sclerosis
Teva Branded Pharmaceutical Products R&D, Inc. 374
Not applicableStudy completedNCT01804647
What this trial is testing

Longitudinal Therapeutically Non-interventional Study of MSRV-Env Burden in Patients With Multiple Sclerosis Disease

Who this might be right for
Multiple Sclerosis (MS)Relapsing-Remitting MSPrimary Progressive MS+2 more
GeNeuro Innovation SAS 58
Testing effectiveness (Phase 2)Study completedNCT02913157
What this trial is testing

Hydroxychloroquine in Primary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Primary Progressive
University of Calgary 35
Not applicableNot Yet RecruitingNCT07831928
What this trial is testing

Evaluation of an Online, On Demand Multimodal Wellness Program to Reduce Fatigue and Improve Quality of Life in Progressive Multiple Sclerosis.

Who this might be right for
Primary Progressive Multiple Sclerosis (PPMS)Secondary Progressive Multiple Sclerosis (SPMS)
University of Iowa 118
Not applicableStudy completedNCT05974852
What this trial is testing

Effect of Ocrelizumab on Choroid Plexus Changes in Patients With PPMS

Who this might be right for
Primary Progressive Multiple Sclerosis
State University of New York at Buffalo 732
Testing effectiveness (Phase 2)Study completedNCT01191996
What this trial is testing

Safety Study of an Immunomodulating Microparticle to Treat Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple SclerosisPrimary Progressive Multiple Sclerosis
Innate Immunotherapeutics 34
Early research (Phase 1)Looking for participantsNCT06680037
What this trial is testing

Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders

Who this might be right for
B-cell Mediated Autoimmune Disorders
TG Therapeutics, Inc. 100
Large-scale testing (Phase 3)Active Not RecruitingNCT04548999
What this trial is testing

Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)

Who this might be right for
Multiple Sclerosis
Hoffmann-La Roche 769
Not applicableStudy completedNCT04120675
What this trial is testing

Efficacy of Early Harvest Olive Oil in Cognition of Primary (PPMS) or Secondary (SPMS) Progressive Multiple Sclerosis

Who this might be right for
Progressive Multiple Sclerosis
Aristotle University Of Thessaloniki 30
Large-scale testing (Phase 3)Ended earlyNCT00731692
What this trial is testing

This Was an Open-label, Single-arm Extension Study (CFTY720D2306E1) to a Double-blind, Randomized Multicenter, Placebo-controlled, Parallel-group Core Study (CFTY720D2306) in PPMS.

Who this might be right for
Primary Progressive Multiple Sclerosis
Novartis Pharmaceuticals 970
Testing effectiveness (Phase 2)Ended earlyNCT03362294
What this trial is testing

Safety and Efficacy of Monthly Long-acting IM Injection of 25mg or 40 mg GA Depot in Subjects With PPMS

Who this might be right for
Primary Progressive Multiple Sclerosis
Mapi Pharma Ltd. 30
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