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Results for “Primary Progressive Multiple Sclerosis (PPMS)”

27 trials

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Showing 20 of 27 results

Large-scale testing (Phase 3)Ended earlyNCT00731692
What this trial is testing

This Was an Open-label, Single-arm Extension Study (CFTY720D2306E1) to a Double-blind, Randomized Multicenter, Placebo-controlled, Parallel-group Core Study (CFTY720D2306) in PPMS.

Who this might be right for
Primary Progressive Multiple Sclerosis
Novartis Pharmaceuticals 970
Early research (Phase 1)Study completedNCT04943289
What this trial is testing

Intrathecal Administration of DUOC-01 in Adults With Primary Progressive Multiple Sclerosis

Who this might be right for
Primary Progressive Multiple Sclerosis
Joanne Kurtzberg, MD 20
Early research (Phase 1)Study completedNCT06683612
What this trial is testing

PET Study of PIPE-791 in Healthy Volunteers and Volunteers With PrMS and IPF

Who this might be right for
Idiopathic Pulmonary Fibrosis (IPF)Idiopathic Pulmonary FibrosisMultiple Sclerosis+6 more
Contineum Therapeutics 16
Not applicableActive Not RecruitingNCT03983681
What this trial is testing

Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in MS

Who this might be right for
Multiple Sclerosis
Kessler Foundation 120
Large-scale testing (Phase 3)Study completedNCT02688985
What this trial is testing

Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS) or Primary Progressive Multiple Sclerosis (PPMS)

Who this might be right for
Relapsing Multiple SclerorsisMultiple Sclerosis, Primary Progressive
Genentech, Inc. 131
Large-scale testing (Phase 3)UnknownNCT02220244
What this trial is testing

Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
MedDay Pharmaceuticals SA 105
Not applicableStudy completedNCT05974852
What this trial is testing

Effect of Ocrelizumab on Choroid Plexus Changes in Patients With PPMS

Who this might be right for
Primary Progressive Multiple Sclerosis
State University of New York at Buffalo 732
Testing effectiveness (Phase 2)Study completedNCT01191996
What this trial is testing

Safety Study of an Immunomodulating Microparticle to Treat Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple SclerosisPrimary Progressive Multiple Sclerosis
Innate Immunotherapeutics 34
Large-scale testing (Phase 3)Active Not RecruitingNCT05441488
What this trial is testing

Masitinib in the Treatment of Patients With Primary Progressive or Non-active Secondary Progressive Multiple Sclerosis

Who this might be right for
Progressive Multiple Sclerosis
AB Science 800
Not applicableNot Yet RecruitingNCT06171334
What this trial is testing

Remote Ischemic Conditioning in PPMS

Who this might be right for
Multiple Sclerosis
University of Calgary 45
Not applicableUnknownNCT05229861
What this trial is testing

The Influence of HIIT Versus MCT on Cardiorespiratory Fitness in PPMS

Who this might be right for
Primary Progressive Multiple SclerosisExerciseCardiorespiratory Fitness
Klinik Valens 61
Not applicableActive Not RecruitingNCT03455582
What this trial is testing

Cognition Evolution and MRI Markers in PPMS Patients on 2 Years

Who this might be right for
Multiple Sclerosis, Primary Progressive
University Hospital, Bordeaux 66
Not applicableStudy completedNCT01080014
What this trial is testing

Correlation Between Multiple Sclerosis Functional Composite (MSFC) and Expanded Disability Status Scale (EDSS) in Patients With Multiple Sclerosis (MS) in Argentina

Who this might be right for
Multiple Sclerosis
Merck KGaA, Darmstadt, Germany 252
Testing effectiveness (Phase 2)Study completedNCT02913157
What this trial is testing

Hydroxychloroquine in Primary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Primary Progressive
University of Calgary 35
Early research (Phase 1)Temporarily pausedNCT06677710
What this trial is testing

IDP-023 g-NK Cells Plus Ocrelizumab in Patients With Progressive Multiple Sclerosis

Who this might be right for
Multiple SclerosisPrimary Progressive Multiple Sclerosis (PPMS)Secondary Progressive Multiple Sclerosis (SPMS)+8 more
Indapta Therapeutics, INC. 34
Large-scale testing (Phase 3)Active Not RecruitingNCT04548999
What this trial is testing

Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)

Who this might be right for
Multiple Sclerosis
Hoffmann-La Roche 769
Not applicableStudy completedNCT05974839
What this trial is testing

Effect of Ocrelizumab on Cortical Lesion Accumulation in Patients With PPMS (ORATORIO-Cortical)

Who this might be right for
Primary Progressive Multiple Sclerosis
State University of New York at Buffalo 732
Large-scale testing (Phase 3)Study completedNCT04458051
What this trial is testing

Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)

Who this might be right for
Primary Progressive Multiple Sclerosis
Sanofi 767
Large-scale testing (Phase 3)Study completedNCT00087529
What this trial is testing

Evaluate the Safety and Efficacy of Rituximab in Adults With Primary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Genentech, Inc. 439
Early research (Phase 1)Looking for participantsNCT06680037
What this trial is testing

Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders

Who this might be right for
B-cell Mediated Autoimmune Disorders
TG Therapeutics, Inc. 32
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