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Results for “Primary T-cell Immunodeficiency Disorders”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT00028236
What this trial is testing

Stem Cell Gene Therapy to Treat X-Linked Severe Combined Immunodeficiency (XSCID)

Who this might be right for
Severe Combined Immunodeficiency
National Institute of Allergy and Infectious Diseases (NIAID) 3
Testing effectiveness (Phase 2)Looking for participantsNCT06839456
What this trial is testing

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

Who this might be right for
LeukemiaHigh Risk Acute Lymphoblastic LeukemiaHigh Risk Acute Myeloid Leukemia+11 more
Children's Hospital of Philadelphia 100
Early research (Phase 1)Ended earlyNCT02231710
What this trial is testing

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

Who this might be right for
Primary Immune Deficiency DisordersHemophagocytic LymphohistiocytosisInherited Bone Marrow Failure Syndrome+2 more
Bellicum Pharmaceuticals 1
Not applicableActive Not RecruitingNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Testing effectiveness (Phase 2)Ended earlyNCT02065869
What this trial is testing

Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant

Who this might be right for
Acute Lymphoblastic LeukemiaLeukemia, Acute Myeloid (AML), ChildLymphoma, Non-Hodgkin+10 more
Bellicum Pharmaceuticals 187
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07697118
What this trial is testing

Study Evaluating a Gene Therapy for IPEX Syndrome Through the Expression of FOXP3 on Deficient T Cells to Produce Tregs-like.

Who this might be right for
The Immune Dysregulation Polyendocrinopathy Enteropathy X-linked Syndrome is a Primary Immunodeficiency Caused by Pathogenic Variants in Forkhead Box Protein 3
Assistance Publique - Hôpitaux de Paris 5
Testing effectiveness (Phase 2)Study completedNCT00576407
What this trial is testing

Thymus Transplantation in DiGeorge Syndrome #668

Who this might be right for
DiGeorge SyndromeComplete Typical DiGeorge Anomaly
Sumitomo Pharma Switzerland GmbH 26
Testing effectiveness (Phase 2)Ended earlyNCT00579137
What this trial is testing

Allogeneic SCT Of Pts With SCID And Other Primary Immunodeficiency Disorders

Who this might be right for
Severe Combined Immunodeficiency DiseaseSevere Primary Immunodeficiency DisorderUndefined T Cell Deficiency Disorder+1 more
Baylor College of Medicine 3
Not applicableActive Not RecruitingNCT05321407
What this trial is testing

COVID-19 Vaccine Responses in PIDD Subjects

Who this might be right for
X-linked AgammaglobulinemiaXLAPrimary Immune Deficiency+4 more
Duke University 100
Early research (Phase 1)Looking for participantsNCT04691622
What this trial is testing

Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts

Who this might be right for
Viral InfectionHematopoietic Stem Cell Transplantation (HSCT)Primary Immunodeficiency Disorders (PID)
Children's National Research Institute 48
Early research (Phase 1)Study completedNCT04723602
What this trial is testing

Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults

Who this might be right for
Ebola Virus DiseaseMarburg Virus Disease
Albert B. Sabin Vaccine Institute 32
Testing effectiveness (Phase 2)Looking for participantsNCT04339777
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

Who this might be right for
Lymphoproliferative DisordersAutoimmune LymphoproliferativeImmune System Diseases+2 more
National Cancer Institute (NCI) 66
Not applicableNo Longer AvailableNCT02915406
What this trial is testing

CliniMACs HUD for T Cell Depletion

Who this might be right for
x Linked Combined Immunodeficiency
University of Miami
Not applicableStudy completedNCT00112593
What this trial is testing

Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Undifferentiated LeukemiaAdult Acute Lymphoblastic Leukemia in Remission+176 more
Fred Hutchinson Cancer Center 5
Testing effectiveness (Phase 2)Ended earlyNCT02127892
What this trial is testing

SCID Bu/Flu/ATG Study With T Cell Depletion

Who this might be right for
Severe Combined Immunodeficiency
Neena Kapoor, M.D. 9
Not applicableNo Longer AvailableNCT02822495
What this trial is testing

Expanded Access Protocol for Tabelecleucel for Patients With Epstein-Barr Virus-Associated Viremia or Malignancies

Who this might be right for
Epstein-Barr Virus (EBV) InfectionsLymphoproliferative DisordersEBV+ Associated Lymphoma+9 more
Atara Biotherapeutics
Not applicableStudy completedNCT00908544
What this trial is testing

New Era Study: Treatment With Multi Drug Class (MDC) HAART in HIV Infected Patients

Who this might be right for
HIV Infections
MUC Research GmbH 47
Not applicableStudy completedNCT00113464
What this trial is testing

Developing Newborn Screening for Infants With Primary Immunodeficiency

Who this might be right for
Immune System Diseases
National Human Genome Research Institute (NHGRI) 100
Testing effectiveness (Phase 2)Study completedNCT00110045
What this trial is testing

Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant

Who this might be right for
Cancer
European Organisation for Research and Treatment of Cancer - EORTC 171
Not applicableStudy completedNCT00845416
What this trial is testing

Newborn Screening for Severe Combined Immunodeficiency (SCID) in a High-Risk Population

Who this might be right for
Severe Combined ImmunodeficiencyT Cell Lymphocytopenia
University of California, San Francisco 1,800
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