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Results for “Prodromal Stage”

46 trials

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Enrolling by Invitation

Showing 20 of 46 results

Testing effectiveness (Phase 2)Ended earlyNCT04592341
What this trial is testing

Evaluate the Pharmacodynamic (PD) Effects of Once Weekly Administration of Gantenerumab in Participants With Early Alzheimer's Disease (AD)

Who this might be right for
Alzheimer Disease
Hoffmann-La Roche 192
Not applicableUnknownNCT04137926
What this trial is testing

Study on the Diagnosis and Intervention of New Biomarkers on the Prodromal Stage of Alzheimer's Disease

Who this might be right for
Alzheimer's Disease
Shanghai Mental Health Center 360
Testing effectiveness (Phase 2)Active Not RecruitingNCT05686551
What this trial is testing

GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease

Who this might be right for
Huntington Disease
Hoffmann-La Roche 301
Not applicableEnded earlyNCT04846426
What this trial is testing

Amyloid Prediction in Early Stage Alzheimer's Disease From Acoustic and Linguistic Patterns of Speech - FUTURE Extension

Who this might be right for
Alzheimer DiseasePreclinical Alzheimer's DiseaseProdromal Alzheimer's Disease+2 more
Novoic Limited 67
Testing effectiveness (Phase 2)Looking for participantsNCT04588285
What this trial is testing

Ambroxol in New and Early DLB, A Phase IIa Multicentre Randomized Controlled Double Blind Clinical Trial

Who this might be right for
Dementia With Lewy Bodies
Helse Fonna 180
Not applicableLooking for participantsNCT02420470
What this trial is testing

The Early Warning System for the Diabetic Encephalopathy

Who this might be right for
Diabetes Mellitus Type 2Mild Cognitive ImpairmentMetabolic Syndrome X
Tang-Du Hospital 300
Not applicableUnknownNCT04851496
What this trial is testing

Amyloid Prediction in Early Stage Alzheimer's Disease From Acoustic and Linguistic Patterns of Speech - PAST Extension

Who this might be right for
Alzheimer DiseasePreclinical Alzheimer's DiseaseProdromal Alzheimer's Disease+2 more
Novoic Limited 80
Testing effectiveness (Phase 2)Active Not RecruitingNCT04639050
What this trial is testing

Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer's Disease

Who this might be right for
Alzheimers Disease
Hoffmann-La Roche 241
Not applicableEnded earlyNCT04951284
What this trial is testing

Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping - FUTURE Extension

Who this might be right for
Alzheimer DiseasePreclinical Alzheimer's DiseaseProdromal Alzheimer's Disease+2 more
Novoic Limited 42
Early research (Phase 1)Study completedNCT04566003
What this trial is testing

Evaluation Comparing Tau PET Radiotracers, [18F]GTP1 and [18F]PI-2620 or [18F]MK-6240 in Subjects With Normal Cognition or Prodromal to Moderate Alzheimer's Disease

Who this might be right for
Alzheimer Disease (AD)
Genentech, Inc. 40
Not applicableEnrolling By InvitationNCT05826457
What this trial is testing

North American Prodromal Synucleinopathy Consortium Stage 2

Who this might be right for
REM Sleep Behavior DisorderParkinson DiseaseLewy Body Dementia+3 more
Washington University School of Medicine 500
Large-scale testing (Phase 3)Ended earlyNCT03114657
What this trial is testing

Crenezumab Versus Placebo to Evaluate the Efficacy and Safety in Participants With Prodromal to Mild Alzheimer's Disease (AD)

Who this might be right for
Alzheimer's Disease
Hoffmann-La Roche 806
Large-scale testing (Phase 3)Ended earlyNCT02760602
What this trial is testing

Solanezumab (LY2062430) in Participants With Prodromal Alzheimer's Disease

Who this might be right for
Alzheimer's Disease
Eli Lilly and Company 26
Not applicableLooking for participantsNCT03206190
What this trial is testing

The preSPG4 Study - Studying the Prodromal and Early Phase of SPG4

Who this might be right for
Hereditary Spastic ParaplegiaHereditary, Spastic Paraplegia, Autosomal Dominant
University Hospital Tuebingen 200
Testing effectiveness (Phase 2)Study completedNCT04867616
What this trial is testing

Test the Efficacy, Safety, and Tolerability of Bepranemab (UCB0107) in Patients With Mild Cognitive Impairment or Mild Alzheimer's Disease (AD)

Who this might be right for
Alzheimer's Disease
UCB Biopharma SRL 466
Not applicableUnknownNCT04853485
What this trial is testing

Repetitive Transcranial Magnetic Stimulation in Early Psychosis and The Functional Connectivity Biotypes

Who this might be right for
Schizophrenia; PsychosisFirst Episode PsychosisClinical High Risk
Shanghai Jiao Tong University School of Medicine 300
Testing effectiveness (Phase 2)Looking for participantsNCT07477431
What this trial is testing

Levetiracetam for Persons at Risk for Alzheimer's Disease

Who this might be right for
Hippocampal HyperactivationProdromal Alzheimer Disease
Sunnybrook Health Sciences Centre 40
Large-scale testing (Phase 3)Active Not RecruitingNCT03887455
What this trial is testing

Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease

Who this might be right for
Early Alzheimer's Disease
Eisai Inc. 1,906
Testing effectiveness (Phase 2)Looking for participantsNCT05462106
What this trial is testing

Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

Who this might be right for
Amyloid PlaqueBeta-AmyloidDSAD+2 more
AC Immune SA 304
Not applicableNot Yet RecruitingNCT06993142
What this trial is testing

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

Who this might be right for
Parkinson DiseaseProdromal StageNeurodegenerative Diseases+8 more
Radboud University Medical Center 600
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