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Results for “Programmed Cell Death 1 Inhibitor”

70 trials

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Showing 20 of 70 results

Testing effectiveness (Phase 2)UnknownNCT05311566
What this trial is testing

PD-1 Antibody Plus Chemoradiotherapy for IB2-IIIB Cervical Cancer

Who this might be right for
Cervical CarcinomaChemoradiotherapyAnti-programmed Cell Death Receptor 1+6 more
Lei Li 92
Large-scale testing (Phase 3)Study completedNCT04246177
What this trial is testing

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

Who this might be right for
Carcinoma, Hepatocellular
Merck Sharp & Dohme LLC 479
Testing effectiveness (Phase 2)Study completedNCT00882869
What this trial is testing

XIAP Antisense AEG35156 in Combination With Sorafenib in Patients With Advanced Hepatocellular Carcinoma (HCC)

Who this might be right for
Advanced Hepatocellular Carcinoma
Aegera Therapeutics 75
Not applicableUnknownNCT04922541
What this trial is testing

Multi-center Observational Study on the Progression of Atherosclerotic Plaques in Anti-PD-1 mAb Treated Tumor Patients by Artery Ultrasound Follow-up

Who this might be right for
Plaque, AtheroscleroticProgrammed Cell Death Protein 1 Inhibitor
Second Affiliated Hospital, School of Medicine, Zhejiang University 50
Testing effectiveness (Phase 2)Ended earlyNCT03116529
What this trial is testing

Neoadjuvant Durvalumab and Tremelimumab Plus Radiation for High Risk Soft-Tissue Sarcoma

Who this might be right for
Soft Tissue Sarcoma
University of Maryland, Baltimore 22
Not applicableUnknownNCT05123287
What this trial is testing

A Perspective, Self-control Study on the Progression of Carotid Plaques in Anti-PD-1 mAb Treated Tumor Patients by Artery Ultrasound Follow-up

Who this might be right for
Plaque, AtheroscleroticImmune Checkpoint InhibitorsProgrammed Cell Death Protein 1 Inhibitor+2 more
Second Affiliated Hospital, School of Medicine, Zhejiang University 50
Testing effectiveness (Phase 2)Study completedNCT04305041
What this trial is testing

Substudy 02A: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents in Participants With Programmed Cell-death 1 (PD-1) Refractory Melanoma (MK-3475-02A/KEYMAKER-U02)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 100
Large-scale testing (Phase 3)WithdrawnNCT06513884
What this trial is testing

HB-202/HB-201 With Pembrolizumab in Patients With HPV16+ Recurrent/Metastatic Oropharyngeal Cancer

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma Recurrent
Hookipa Biotech GmbH
Testing effectiveness (Phase 2)Looking for participantsNCT06996782
What this trial is testing

A Platform Study in Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
Advanced or Metastatic Non-small Cell Lung Cancer
AstraZeneca 152
Testing effectiveness (Phase 2)Study completedNCT03910660
What this trial is testing

A Trial of BXCL701 and Pembrolizumab in Patients With mCRPC Either Small Cell Neuroendocrine Prostate Cancer or Adenocarcinoma Phenotype.

Who this might be right for
Prostate CancerNeuroendocrine TumorsSmall Cell Carcinoma
BioXcel Therapeutics Inc 98
Testing effectiveness (Phase 2)Active Not RecruitingNCT05565378
What this trial is testing

A Platform Study of Novel Immunotherapy Combinations in Participants With Previously Untreated, Advanced/Metastatic Non-Small-Cell Lung Cancer

Who this might be right for
Lung Cancer, Non-Small Cell
GlaxoSmithKline 351
Early research (Phase 1)WithdrawnNCT03920839
What this trial is testing

INCMGA00012 Plus Chemotherapy in Participants With Advanced Solid Tumors (POD1UM-105)

Who this might be right for
Advanced and/or Metastatic Solid TumorsStage IIIB Not Amenable to Curative Therapy to Stage IV Non-small Cell Lung CancerAdvanced/Metastatic Unresectable Malignant Pleural Mesothelioma
Incyte Corporation
Early research (Phase 1)Study completedNCT04393506
What this trial is testing

Inductive Camrelizumab and Apatinib for Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma

Who this might be right for
Oral CancerVEGFR2 InhibitorProgrammed Cell Death 1 Inhibitor+1 more
Shanghai Jiao Tong University School of Medicine 21
Large-scale testing (Phase 3)WithdrawnNCT03342352
What this trial is testing

Nivolumab Plus Epacadostat in Combination With Chemotherapy Versus the EXTREME Regimen in Squamous Cell Carcinoma of the Head and Neck (CheckMate 9NA/ECHO-310)

Who this might be right for
Head and Neck Cancer
Incyte Corporation
Testing effectiveness (Phase 2)Ended earlyNCT00768339
What this trial is testing

A Phase 1-2, Multicenter, Open-Label Study of AEG35156 in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia and Indolent B-Cell Lymphomas

Who this might be right for
Leukemia, Lymphocytic, Chronic, B-CellLymphoma, B-Cell
Aegera Therapeutics 25
Early research (Phase 1)Ended earlyNCT04458259
What this trial is testing

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Who this might be right for
Neoplasm Metastasis
Pfizer 88
Testing effectiveness (Phase 2)Study completedNCT03322540
What this trial is testing

Pembrolizumab Plus Epacadostat vs Pembrolizumab Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-654-05/ECHO-305-05)

Who this might be right for
Lung Cancer
Incyte Corporation 154
Not applicableUnknownNCT06364046
What this trial is testing

Efficacy and Safety of DEB-BACE Combined With Serplulimab in First-line Treatment of SCLC

Who this might be right for
CarcinomaSmall Cell Lung Cancer
The Central Hospital of Lishui City 56
Large-scale testing (Phase 3)Active Not RecruitingNCT06790966
What this trial is testing

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Recurrent Head and Neck CancerMetastatic Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+2 more
PDS Biotechnology Corp. 252
Large-scale testing (Phase 3)Study completedNCT03260894
What this trial is testing

Pembrolizumab (MK-3475) Plus Epacadostat vs Standard of Care in mRCC (KEYNOTE-679/ECHO-302)

Who this might be right for
Renal Cell Carcinoma (RCC)
Incyte Corporation 129
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