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Results for “Programmed Cell Death 1 Inhibitor”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Ended earlyNCT06790966
What this trial is testing

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Recurrent Head and Neck CancerMetastatic Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+2 more
PDS Biotechnology Corp. 12
Testing effectiveness (Phase 2)Study completedNCT04305041
What this trial is testing

Substudy 02A: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents in Participants With Programmed Cell-death 1 (PD-1) Refractory Melanoma (MK-3475-02A/KEYMAKER-U02)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT04626518
What this trial is testing

Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B/KEYMAKER-U03)

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 370
Early research (Phase 1)Study completedNCT04473716
What this trial is testing

Neoadjuvant Toripalimab and Paclitaxel/Cisplatin on Pathological Response in Oral Squamous Cell Carcinoma Patients

Who this might be right for
Oral CancerInduction ChemotherapyProgrammed Cell Death 1 Inhibitor+1 more
Shanghai Jiao Tong University School of Medicine 20
Testing effectiveness (Phase 2)Study completedNCT04669899
What this trial is testing

Study of JTX-8064, as Monotherapy and in Combination With a PD-1 Inhibitor, in Adult Subjects With Advanced Refractory Solid Tumors

Who this might be right for
Cancer
Jounce Therapeutics, Inc. 190
Early research (Phase 1)Study completedNCT04881045
What this trial is testing

Study to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors.

Who this might be right for
Non-Small Cell Lung CancerSquamous Cell Carcinoma of the Head and NeckOvarian Cancer
Pfizer 29
Testing effectiveness (Phase 2)Ended earlyNCT03116529
What this trial is testing

Neoadjuvant Durvalumab and Tremelimumab Plus Radiation for High Risk Soft-Tissue Sarcoma

Who this might be right for
Soft Tissue Sarcoma
University of Maryland, Baltimore 22
Testing effectiveness (Phase 2)Looking for participantsNCT06228066
What this trial is testing

Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER)

Who this might be right for
Small Cell Carcinoma of the BladderHigh Grade Neuroendocrine Tumors of the Urinary Tract
National Cancer Institute (NCI) 45
Large-scale testing (Phase 3)Study completedNCT03361865
What this trial is testing

Pembrolizumab in Combination With Epacadostat or Placebo in Cisplatin-ineligible Urothelial Carcinoma (KEYNOTE-672/ECHO-307)

Who this might be right for
UC (Urothelial Cancer)
Incyte Corporation 93
Testing effectiveness (Phase 2)Active Not RecruitingNCT06773910
What this trial is testing

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

Who this might be right for
Limited Stage Small Cell Lung Cancer
SCRI Development Innovations, LLC 250
Testing effectiveness (Phase 2)Ended earlyNCT00557596
What this trial is testing

A Phase 1-2, XIAP Antisense AEG35156 With Gemcitabine in Patients With Advanced Pancreatic Cancer

Who this might be right for
CarcinomaPancreas
Aegera Therapeutics 48
Testing effectiveness (Phase 2)Active Not RecruitingNCT03678883
What this trial is testing

9-ING-41 in Patients With Advanced Cancers

Who this might be right for
CancerPancreatic CancerSarcoma+22 more
Actuate Therapeutics Inc. 350
Large-scale testing (Phase 3)Study completedNCT03374488
What this trial is testing

Pembrolizumab + Epacadostat vs Pembrolizumab + Placebo in Recurrent or Progressive Metastatic Urothelial Carcinoma

Who this might be right for
UC (Urothelial Cancer)
Incyte Corporation 84
Early research (Phase 1)Study completedNCT01062152
What this trial is testing

Dose-Ranging Study of Telintra® Tablets + Revlimid® in Patients With Non-Deletion (5q) Low to Intermediate-1 Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Myelodysplastic Syndrome
Telik 19
Large-scale testing (Phase 3)Looking for participantsNCT06712355
What this trial is testing

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

Who this might be right for
Extensive-stage Small-cell Lung Cancer
BioNTech SE 621
Large-scale testing (Phase 3)Active Not RecruitingNCT04380636
What this trial is testing

Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)

Who this might be right for
Lung NeoplasmsCarcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC 870
Testing effectiveness (Phase 2)UnknownNCT05311566
What this trial is testing

PD-1 Antibody Plus Chemoradiotherapy for IB2-IIIB Cervical Cancer

Who this might be right for
Cervical CarcinomaChemoradiotherapyAnti-programmed Cell Death Receptor 1+6 more
Lei Li 92
Testing effectiveness (Phase 2)Study completedNCT03322540
What this trial is testing

Pembrolizumab Plus Epacadostat vs Pembrolizumab Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-654-05/ECHO-305-05)

Who this might be right for
Lung Cancer
Incyte Corporation 154
Large-scale testing (Phase 3)Study completedNCT03867084
What this trial is testing

Safety and Efficacy of Pembrolizumab (MK-3475) Versus Placebo as Adjuvant Therapy in Participants With Hepatocellular Carcinoma (HCC) and Complete Radiological Response After Surgical Resection or Local Ablation (MK-3475-937 / KEYNOTE-937)

Who this might be right for
Hepatocellular Carcinoma
Merck Sharp & Dohme LLC 959
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07776340
What this trial is testing

Induction PD-1 Inhibitor and Chemotherapy Followed by Chemoradiotherapy in Unresectable or Inoperable HPV-negative LA-HNSCC

Who this might be right for
HPV-unrelated Head and Neck Squamous Cell Carcinoma
Fudan University 104
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