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Results for “Programmed Cell Death 1 Ligand 1(PDL1, PD-L1)”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT03783078
What this trial is testing

Pembrolizumab (MK-3475) as First-line Therapy for Advanced Merkel Cell Carcinoma (MK-3475-913)

Who this might be right for
Merkel Cell Carcinoma
Merck Sharp & Dohme LLC 55
Large-scale testing (Phase 3)Study completedNCT02775435
What this trial is testing

Carboplatin-Paclitaxel/Nab-Paclitaxel Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With First Line Metastatic Squamous Non-small Cell Lung Cancer (MK-3475-407/KEYNOTE-407)

Who this might be right for
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC 559
Early research (Phase 1)Active Not RecruitingNCT05361395
What this trial is testing

First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Who this might be right for
Extensive Stage Small Cell Lung Cancer
Amgen 184
Not applicableUnknownNCT05533086
What this trial is testing

PD-L1 PET Imaging in Patients With the Immunotherapy for Non-small Cell Lung Cancer

Who this might be right for
NSCLC Stage IVPD-L1 Gene Amplification
Xiaohua Zhu 20
Testing effectiveness (Phase 2)Looking for participantsNCT07079631
What this trial is testing

A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
BioNTech SE 482
Large-scale testing (Phase 3)Active Not RecruitingNCT03271372
What this trial is testing

Adjuvant Avelumab in Merkel Cell Cancer

Who this might be right for
Stage III Merkel Cell Carcinoma AJCC v8Stage IIIB Merkel Cell Carcinoma AJCC v8Stage IIIA Merkel Cell Carcinoma AJCC v8
University of Washington 101
Testing effectiveness (Phase 2)UnknownNCT04940637
What this trial is testing

UNITO-001- Study in HRR/PDL1 Positive MPM/NSCLC

Who this might be right for
Lung CancerMesothelioma
University of Turin, Italy 70
Early research (Phase 1)UnknownNCT04603846
What this trial is testing

Anti-PD-L1 Antibody ZKAB001 Combined With Albumin-bound Paclitaxel in Advanced Urothelial Carcinoma

Who this might be right for
Advanced Urothelial Carcinoma
Lee's Pharmaceutical Limited 20
Large-scale testing (Phase 3)Active Not RecruitingNCT03725059
What this trial is testing

Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

Who this might be right for
Breast Cancer
Merck Sharp & Dohme LLC 1,240
Testing effectiveness (Phase 2)WithdrawnNCT03167177
What this trial is testing

QUILT-3.046: NANT Melanoma Vaccine: Combination Immunotherapy in Subjects With Melanoma Who Have Progressed On or After Chemotherapy and PD-1/PD-L1 Therapy

Who this might be right for
Melanoma
ImmunityBio, Inc.
Large-scale testing (Phase 3)Study completedNCT03834493
What this trial is testing

Study of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-641/KEYNOTE-641)

Who this might be right for
Prostatic Neoplasms
Merck Sharp & Dohme LLC 1,244
Testing effectiveness (Phase 2)Study completedNCT02155647
What this trial is testing

Avelumab in Participants With Merkel Cell Carcinoma (JAVELIN Merkel 200)

Who this might be right for
Carcinoma, Merkel Cell
EMD Serono Research & Development Institute, Inc. 204
Not applicableStudy completedNCT07192926
What this trial is testing

Body Composition and Blood-Based Prognostic Markers in Immunotherapy-Treated Metastatic Non-Small Cell Lung Cancer

Who this might be right for
Metastatic Non-small Cell Lung CancerNeoplasm
Ankara Etlik City Hospital 155
Not applicableLooking for participantsNCT06537908
What this trial is testing

Anti-PD-1/PD-L1 Antibodies Plus Anti-VEGF Antibody Treatment in Patients With Advanced-Stage HCC

Who this might be right for
Hepatocellular Carcinoma
Shanghai Zhongshan Hospital 50
Early research (Phase 1)Ended earlyNCT03809624
What this trial is testing

Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer

Who this might be right for
Metastatic Solid TumorsNon-small Cell Lung CancerMelanoma+6 more
Inhibrx Biosciences, Inc 160
Testing effectiveness (Phase 2)WithdrawnNCT06245291
What this trial is testing

Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infection

Who this might be right for
Hepatitis B, Chronic
Arbutus Biopharma Corporation
Not applicableUnknownNCT05527808
What this trial is testing

A Single-arm Exploratory Study of Neoadjuvant Therapy

Who this might be right for
Lung Adenocarcinoma
Jun Liu 28
Very early researchActive Not RecruitingNCT02812420
What this trial is testing

Durvalumab and Tremelimumab in Treating Patients With Muscle-Invasive, High-Risk Urothelial Cancer That Cannot Be Treated With Cisplatin-Based Therapy Before Surgery

Who this might be right for
HydronephrosisInfiltrating Bladder Urothelial Carcinoma Sarcomatoid VariantInfiltrating Bladder Urothelial Carcinoma, Micropapillary Variant+16 more
M.D. Anderson Cancer Center 54
Testing effectiveness (Phase 2)Active Not RecruitingNCT04417660
What this trial is testing

Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma

Who this might be right for
Thymic Epithelial TumorRecurrent ThymomaThymic Cancer
National Cancer Institute (NCI) 9
Testing effectiveness (Phase 2)Study completedNCT04165096
What this trial is testing

KEYMAKER-U01 Substudy 3: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Participants With Advanced Non-small Cell Lung Cancer (NSCLC), Previously Treated With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Therapy (MK-3475-01C/KEYMAKER-U01C)

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC 128
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