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Results for “Proteostasis Deficiencies”

1,813 trials

Showing 20 of 1,813 results

Not applicableLooking for participantsNCT06051123
What this trial is testing

Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) Patients

Who this might be right for
ALSFTDALS (Amyotrophic Lateral Sclerosis)Frontal Temporal Dementia (FTD)
Centre hospitalier de l'Université de Montréal (CHUM) 150
Not applicableWithdrawnNCT03892382
What this trial is testing

Repetitive Transcranial Magnetic Stimulation as Therapy for Apathy in Amyotrophic Lateral Sclerosis

Who this might be right for
Amyotrophic Lateral Sclerosis
Jagiellonian University
Large-scale testing (Phase 3)Looking for participantsNCT07052903
What this trial is testing

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals 1,750
Not applicableLooking for participantsNCT07648303
What this trial is testing

Prevalence of Cardiac Thrombi in Cardiac Amyloidosis

Who this might be right for
Cardiac Amyloidosis
Centre Hospitalier Universitaire Dijon 200
Not applicableStudy completedNCT03645031
What this trial is testing

Acute Intermittent Hypoxia and Breathing in Neuromuscular Disease

Who this might be right for
Amyotrophic Lateral Sclerosis (ALS)Neuromuscular Diseases
University of Florida 29
Large-scale testing (Phase 3)Study completedNCT00372879
What this trial is testing

Clinical Trial of Vitamin E to Treat Muscular Cramps in Patients With ALS

Who this might be right for
Amyotrophic Lateral Sclerosis
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 32
Large-scale testing (Phase 3)Ended earlyNCT04973137
What this trial is testing

Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients With AL Amyloidosis

Who this might be right for
Light Chain (AL) Amyloidosis
Prothena Biosciences Ltd. 208
Not applicableUnknownNCT06566651
What this trial is testing

Emotion Processing Among Patients With ALS

Who this might be right for
Amyotrophic Lateral SclerosisNeuromuscular DiseasesALS+2 more
University of Aarhus 180
Large-scale testing (Phase 3)Active Not RecruitingNCT04768972
What this trial is testing

FUSION: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ION363 in Amyotrophic Lateral Sclerosis Participants With Fused in Sarcoma Mutations (FUS-ALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
Ionis Pharmaceuticals, Inc. 89
Testing effectiveness (Phase 2)Study completedNCT01854294
What this trial is testing

GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
Genervon Biopharmaceuticals, LLC 12
Not applicableActive Not RecruitingNCT04869631
What this trial is testing

Screening for Amyloidosis Before Aortic Valve Elective Replacement

Who this might be right for
AmyloidosisAortic Valve Stenosis
Charite University, Berlin, Germany 1,000
Testing effectiveness (Phase 2)Study completedNCT03987295
What this trial is testing

Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)

Who this might be right for
Frontotemporal Dementia
Alector Inc. 33
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07743268
What this trial is testing

Personalized Antisense Oligonucleotide Therapy for Participants With TARDBP ALS

Who this might be right for
Amyotrophic Lateral Sclerosis (ALS)
n-Lorem Foundation 6
Large-scale testing (Phase 3)Study completedNCT01994889
What this trial is testing

Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 441
Not applicableStudy completedNCT03824197
What this trial is testing

Auburn University Research on Olive Oil for Alzheimer's Disease (AU-ROOAD)

Who this might be right for
Alzheimer DiseaseCerebral Amyloid Angiopathy
Auburn University 25
Testing effectiveness (Phase 2)WithdrawnNCT05486481
What this trial is testing

Venetoclax, Daratumumab, and Dexamethasone for Systemic Light-Chain Amyloidosis With Translocation (11;14) (ALTITUDE)

Who this might be right for
AL AmyloidosisLight Chain (AL) AmyloidosisSystemic Light Chain Disease
Alfred Chung, MD
Testing effectiveness (Phase 2)UnknownNCT03252600
What this trial is testing

Lenalidomide, Dexamethasone, and Elotuzumab With or Without Cyclophosphamide in Treating Patients With Relapsed Primary Amyloidosis

Who this might be right for
Recurrent Primary Amyloidosis
Barbara Ann Karmanos Cancer Institute 53
Large-scale testing (Phase 3)Study completedNCT03862807
What this trial is testing

Patisiran in Patients With Hereditary Transthyretin-mediated Amyloidosis (hATTR Amyloidosis) Disease Progression Post-Liver Transplant

Who this might be right for
Amyloidosis, FamilialTransthyretin Amyloidosis
Alnylam Pharmaceuticals 24
Testing effectiveness (Phase 2)Study completedNCT00204464
What this trial is testing

Study of the Effects Strengthening Exercises in Individuals With ALS

Who this might be right for
Amyotrophic Lateral Sclerosis
University of Saskatchewan 40
Not applicableEnded earlyNCT02058732
What this trial is testing

Therapeutic Imaging Biomarkers for Amyotrophic Lateral Sclerosis

Who this might be right for
Amyotrophic Lateral Sclerosis
University of Michigan 6
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