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Results for “Proteostasis Deficiencies”

1,717 trials

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Showing 20 of 1,717 results

Testing effectiveness (Phase 2)Looking for participantsNCT07002034
What this trial is testing

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

Who this might be right for
Adjustment Disorder
Reunion Neuroscience Inc 100
Testing effectiveness (Phase 2)Study completedNCT03160898
What this trial is testing

Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
Cytokinetics 458
Not applicableUnknownNCT03321487
What this trial is testing

Blood-Brain Barrier Opening Using MR-Guided Focused Ultrasound in Patients With Amyotrophic Lateral Sclerosis

Who this might be right for
Amyotrophic Lateral Sclerosis
InSightec 8
Testing effectiveness (Phase 2)UnknownNCT04744532
What this trial is testing

IPSC-based Drug Repurposing for ALS Medicine (iDReAM) Study

Who this might be right for
Amyotrophic Lateral Sclerosis
Kyoto University 49
Testing effectiveness (Phase 2)Study completedNCT00245037
What this trial is testing

Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+4 more
OHSU Knight Cancer Institute 147
Not applicableLooking for participantsNCT06933212
What this trial is testing

Effect of the Mediterranean Diet in Patients Affected by CADASIL and Cerebral Amyloid Angiopathy.

Who this might be right for
Cerebral Amyloid AngiopathyCAA - Cerebral Amyloid Angiopathy
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 86
Early research (Phase 1)Study completedNCT03636204
What this trial is testing

A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin (GRN) Mutation

Who this might be right for
HealthyFrontotemporal Dementia
Alector Inc. 64
Not applicableEnded earlyNCT03774784
What this trial is testing

The Natural History of Leukocyte Chemotactic Factor 2 Amyloidosis (ALECT2) Disease

Who this might be right for
AmyloidosisLeukocyte Chemotactic Factor 2 Amyloidosis
Alnylam Pharmaceuticals 26
Early research (Phase 1)WithdrawnNCT02242071
What this trial is testing

Cell Therapy for Motor Neuron Disease/Amyotrophic Lateral Sclerosis

Who this might be right for
Amyotrophic Lateral Sclerosis
Neurogen Brain and Spine Institute
Not applicableActive Not RecruitingNCT04516499
What this trial is testing

Neurofilament Surveillance Project (NSP)

Who this might be right for
Frontotemporal DementiaFrontotemporal Lobar DegenerationFTD-GRN+2 more
The Bluefield Project to Cure Frontotemporal Dementia 342
Testing effectiveness (Phase 2)Looking for participantsNCT07294144
What this trial is testing

Tofersen in Non-SOD1 ALS

Who this might be right for
ALS (Amyotrophic Lateral Sclerosis)
Washington University School of Medicine 30
Testing effectiveness (Phase 2)Looking for participantsNCT06097832
What this trial is testing

Study of NXC-201 CAR-T in Patients With Light Chain (AL) Amyloidosis

Who this might be right for
Light Chain (AL) Amyloidosis
Nexcella Inc. 40
Testing effectiveness (Phase 2)Study completedNCT01083316
What this trial is testing

Bortezomib and Dexamethasone Followed by High-Dose Melphalan and Stem Cell Transplantation for Primary (AL) Amyloidosis

Who this might be right for
Amyloidosis
Boston Medical Center 35
Testing effectiveness (Phase 2)UnknownNCT04140136
What this trial is testing

The Efficacy and Safety of Vitamin E Mixed Tocotrienols In Patients With Amyotrophic Lateral Sclerosis (ALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
University of Malaya 20
Very early researchStudy completedNCT03119558
What this trial is testing

PET/MRI Evaluation of Cardiac Amyloid

Who this might be right for
Cardiac Amyloidosis
Stanford University 9
Not applicableLooking for participantsNCT04265040
What this trial is testing

DZHK TORCH-Plus is a Registry for Patients With Cardiomyopathies and Serves as Source for Cardiovascular Research Studies

Who this might be right for
Non-ischemic CardiomyopathyDCM - Dilated CardiomyopathyHCM - Hypertrophic Cardiomyopathy+5 more
University Hospital Heidelberg 2,040
Not applicableStudy completedNCT03430648
What this trial is testing

Is Tau Protein Linked to Mobility Function?

Who this might be right for
Alzheimer DiseasePhysical Activity
Wake Forest University Health Sciences 37
Not applicableLooking for participantsNCT02945774
What this trial is testing

Molecular Neuroimaging of Neuroinflammation in Neurodegenerative Dementias

Who this might be right for
Frontotemporal Dementia
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 40
Not applicableStudy completedNCT00606918
What this trial is testing

Validation of a New Device to Measure Neuromuscular Disease Progression

Who this might be right for
Amyotrophic Lateral Sclerosis & Other Neuromuscular Disorders
Massachusetts General Hospital 120
Large-scale testing (Phase 3)Ended earlyNCT04944784
What this trial is testing

Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
Cytokinetics 489
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