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Results for “Prothrombin Complex Concentrates”

17 trials

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Showing 17 of 17 results

Testing effectiveness (Phase 2)Study completedNCT05205863
What this trial is testing

Dose-Response in PD and Safety of Cofact Under VKA Anticoagulation

Who this might be right for
Healthy Volunteers
Prothya Biosolutions 69
Early research (Phase 1)Study completedNCT01656330
What this trial is testing

Assess the Effects of 2 Different Prothrombin Complex Concentrates on the Pharmacodynamics of Rivaroxaban in Healthy Adult Volunteers

Who this might be right for
Healthy
Janssen Research & Development, LLC 35
Large-scale testing (Phase 3)Study completedNCT00618098
What this trial is testing

Study of Octaplex (Human Prothrombin Complex Concentrate) and Fresh Frozen Plasma in Patients Under Vitamin K Therapy Antagonist Needing Urgent Surgery or Invasive Procedures

Who this might be right for
Reversal of Anticoagulant Treatment
Octapharma 200
Post-approval studies (Phase 4)Study completedNCT02557672
What this trial is testing

PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding

Who this might be right for
BleedingBlood Loss, SurgicalCardiovascular Surgical Procedures+2 more
Mayo Clinic 106
Post-approval studies (Phase 4)Study completedNCT01128881
What this trial is testing

IMMUNINE Pre-Treatment Study

Who this might be right for
Hemophilia B
Baxalta now part of Shire 57
Large-scale testing (Phase 3)Looking for participantsNCT07094087
What this trial is testing

Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

Who this might be right for
Complex Cardiovascular Surgery With Cardiopulmonary Bypass
CSL Behring 200
Early research (Phase 1)Study completedNCT02074358
What this trial is testing

Assess the Effects of 2 Prothrombin Complex Concentrates on the Pharmacodynamics of Apixaban in Healthy Adult Subjects

Who this might be right for
Anticoagulation
Bristol-Myers Squibb 43
Testing effectiveness (Phase 2)Study completedNCT00004801
What this trial is testing

Phase I/II Study of Monoclonal Factor IX Concentrate for Factor IX Deficiency

Who this might be right for
Hemophilia BFactor IX Deficiency
National Center for Research Resources (NCRR) 3
Large-scale testing (Phase 3)Study completedNCT02263456
What this trial is testing

Compare the Pharmacokinetics and Safety of Replenine®-VF, Replenine® or Other Factor IX in Haemophilia B

Who this might be right for
Haemophilia B
Bio Products Laboratory
Testing effectiveness (Phase 2)Study completedNCT03715348
What this trial is testing

Trial of PCC Versus FFP in Patients Undergoing Heart Surgery

Who this might be right for
BleedingSurgeryTransfusion
Queen Mary University of London 50
Not applicableStudy completedNCT05738642
What this trial is testing

Efficacy and Safety of Early Use PCC in Severe Trauma

Who this might be right for
Severe TraumaTraumatic Shock
Second Affiliated Hospital, School of Medicine, Zhejiang University 380
Testing effectiveness (Phase 2)UnknownNCT04114643
What this trial is testing

Factor Replacement in Surgery

Who this might be right for
Bleeding in Cardiac Surgery
University Health Network, Toronto 103
Not applicableStudy completedNCT02565836
What this trial is testing

Fixed-dose Activated Versus Variable-dose Inactivated Prothrombin Complex Concentrate for Warfarin-associated Major Bleed

Who this might be right for
Hemorrhage
Rush University Medical Center 342
Large-scale testing (Phase 3)Study completedNCT02740335
What this trial is testing

Study of Octaplex, a Four-factor Prothrombin Complex Concentrate (4F-PCC) and Beriplex® P/N (Kcentra) for the Reversal of Vitamin K Antagonist (VKA) Induced Anticoagulation in Patients Needing Urgent Surgery With Significant Bleeding Risk.

Who this might be right for
Significant Bleeding Risk
Octapharma 208
Not applicableStudy completedNCT01187030
What this trial is testing

Appropriateness of Frozen Plasma Use in Canada

Who this might be right for
Blood Component Transfusion
Ottawa Hospital Research Institute 2,580
Post-approval studies (Phase 4)UnknownNCT04534751
What this trial is testing

Factor In the Initial Resuscitation of Severe Trauma 2 Patients

Who this might be right for
Traumatic HemorrhageCoagulopathyMassive Hemorrhage
University Health Network, Toronto 350
Large-scale testing (Phase 3)Looking for participantsNCT04867837
What this trial is testing

Study of OCTAPLEX in Patients With Acute Major Bleeding on DOAC Therapy With Factor Xa Inhibitor

Who this might be right for
Acute Major Bleeding
Octapharma 260