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Results for “Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency”

102 trials

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Showing 20 of 102 results

Not applicableStudy completedNCT00001462
What this trial is testing

Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals

Who this might be right for
EmphysemaLung Diseases, ObstructiveAlpha 1-Antitrypsin Deficiency
National Heart, Lung, and Blood Institute (NHLBI) 60
Not applicableEnded earlyNCT02502201
What this trial is testing

Environment Effect on Six-Minute Walk Test Performance

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha-1 Antitrypsin Deficiency
University of Florida 27
Post-approval studies (Phase 4)Study completedNCT00261833
What this trial is testing

Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency

Who this might be right for
Alpha1-proteinase Inhibitor DeficiencyEmphysema
CSL Behring 180
Early research (Phase 1)Study completedNCT03815396
What this trial is testing

Phase 1 Study to Assess the Safety, PK and PD of INBRX-101 in Adults With Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1 Antitrypsin DeficiencyAATD
Inhibrx Biosciences, Inc 31
Large-scale testing (Phase 3)Active Not RecruitingNCT01983241
What this trial is testing

Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD)

Who this might be right for
Pulmonary Emphysema in Alpha-1 PI Deficiency
Grifols Therapeutics LLC 345
Large-scale testing (Phase 3)Study completedNCT00460096
What this trial is testing

Phase II/III Study of an Alpha-1 Proteinase Inhibitor (Kamada-API) in Individuals With Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Kamada, Ltd. 50
Testing effectiveness (Phase 2)Study completedNCT00067756
What this trial is testing

4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency?

Who this might be right for
Alpha 1-Antitrypsin Deficiency
University of Florida 12
Not applicableStudy completedNCT02922751
What this trial is testing

FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)

Who this might be right for
Biliary AtresiaAlagille SyndromeAlpha1 Anti-Trypsin Deficiency+3 more
Arbor Research Collaborative for Health 552
Not applicableStudy completedNCT01676688
What this trial is testing

Safety Study of Alfalastin (Human Alpha-1 Antitrypsin) Administered at Home

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Laboratoire français de Fractionnement et de Biotechnologies 17
Very early researchActive Not RecruitingNCT07193615
What this trial is testing

Study of YOLT-202 in the Treatment of Alpha-1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)
RenJi Hospital 18
Not applicableLooking for participantsNCT03455686
What this trial is testing

Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease

Who this might be right for
AsthmaChronic Obstructive Pulmonary DiseaseBronchiectasis+5 more
McMaster University 60
Testing effectiveness (Phase 2)Looking for participantsNCT06389877
What this trial is testing

Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Beam Therapeutics Inc. 106
Early research (Phase 1)Study completedNCT03362242
What this trial is testing

Study of ARO-AAT in Normal Adult Volunteers

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Arrowhead Pharmaceuticals 45
Testing effectiveness (Phase 2)Study completedNCT01684410
What this trial is testing

Safety and Tolerability Trial of Inhaled Alpha1-Proteinase Inhibitor (Human), Hydrophobic Chromatography Process (Alpha-1 HC) in Subjects With Cystic Fibrosis

Who this might be right for
Cystic Fibrosis
Grifols Therapeutics LLC 30
Large-scale testing (Phase 3)Enrolling By InvitationNCT02796937
What this trial is testing

Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency

Who this might be right for
Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency
Grifols Therapeutics LLC 290
Large-scale testing (Phase 3)Looking for participantsNCT04204252
What this trial is testing

Phase III, Efficacy and Safety of "Kamada-AAT for Inhalation"

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Kamada, Ltd. 220
Post-approval studies (Phase 4)WithdrawnNCT05466747
What this trial is testing

RYMPHYSIA for Alpha1-Proteinase Inhibitor (A1PI) Therapy in Adults With A1PI Deficiency and Chronic Obstructive Pulmonary Disease (COPD)-Emphysema

Who this might be right for
Chronic Obstructive Pulmonary Disease (COPD)Alpha1-Antitrypsin Deficiency
Takeda
Testing effectiveness (Phase 2)WithdrawnNCT03385395
What this trial is testing

Study Comparing Weekly Intravenous Administration of OctaAlpha1 With a Marketed Preparation Glassia® in Subjects With Alpha-1-antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Octapharma
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07227207
What this trial is testing

TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)
Tessera Therapeutics, Inc. 72
Testing effectiveness (Phase 2)Study completedNCT02947087
What this trial is testing

Alpha-1 Antitrypsin (AAT) Enhances Islet Autograft Survival in Patients With Chronic Pancreatitis

Who this might be right for
Chronic Pancreatitis
Medical University of South Carolina 48
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