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Results for “Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency”

105 trials

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Showing 20 of 105 results

Not applicableStudy completedNCT00001885
What this trial is testing

Identification of Genes Associated With Lung Disease in Patients With Rheumatoid Arthritis

Who this might be right for
HealthyPulmonary FibrosisRheumatoid Arthritis
National Heart, Lung, and Blood Institute (NHLBI) 400
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Post-approval studies (Phase 4)Looking for participantsNCT07135427
What this trial is testing

Genetic Variation in IgG in Alpha 1 Antitrypsin Deficiency

Who this might be right for
Alpha 1-AntitrypsinCOPDAntibody Deficiency
University of Alabama at Birmingham 30
Not applicableLooking for participantsNCT07715617
What this trial is testing

Development of a Prediction Score for the Occurrence of Death or Lung Transplantation in Patients With Emphysema Secondary to Alpha-1-anti-tripsin Deficiency

Who this might be right for
Alpha-1-antitrypsin DeficiencyEmphysemaArtificial Intelligence (AI)+3 more
University Hospital, Bordeaux 230
Not applicableStudy completedNCT07242079
What this trial is testing

Effect Of Pulmonary Rehabilitation in Patients With Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)
University of Parma 50
Testing effectiveness (Phase 2)WithdrawnNCT03385395
What this trial is testing

Study Comparing Weekly Intravenous Administration of OctaAlpha1 With a Marketed Preparation Glassia® in Subjects With Alpha-1-antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Octapharma
Testing effectiveness (Phase 2)UnknownNCT02191839
What this trial is testing

Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery

Who this might be right for
Post Cardiac Surgery Systemic Inflammatory Response
Soroka University Medical Center 20
Large-scale testing (Phase 3)Enrolling By InvitationNCT02796937
What this trial is testing

Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency

Who this might be right for
Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency
Grifols Therapeutics LLC 290
Testing effectiveness (Phase 2)Looking for participantsNCT07227207
What this trial is testing

TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)
Tessera Therapeutics, Inc. 72
Early research (Phase 1)Study completedNCT06186492
What this trial is testing

Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1)

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)
Wave Life Sciences USA, Inc. 47
Not applicableUnknownNCT02915614
What this trial is testing

Effects of Pulmonary Rehabilitation on Skeletal Muscle in COPD Patients

Who this might be right for
Chronic Obstructive Pulmonary Disease
Schön Klinik Berchtesgadener Land 40
Post-approval studies (Phase 4)Study completedNCT00261833
What this trial is testing

Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency

Who this might be right for
Alpha1-proteinase Inhibitor DeficiencyEmphysema
CSL Behring 180
Not applicableStudy completedNCT01810458
What this trial is testing

Liver Fibrosis in Alpha-1 Antitrypsin Deficiency (Liver AATD)

Who this might be right for
Liver FibrosisAlpha-1 Antitrypsin DeficiencyAAT Deficiency+1 more
University of Florida 109
Testing effectiveness (Phase 2)Study completedNCT04474197
What this trial is testing

Evaluation of the Efficacy and Safety of VX-864 in Subjects With the PiZZ Genotype

Who this might be right for
Alpha1-Antitrypsin Deficiency
Vertex Pharmaceuticals Incorporated 44
Post-approval studies (Phase 4)WithdrawnNCT04440488
What this trial is testing

ARALAST NP Alpha-1 Lung Density Chronic Obstructive Pulmonary Disease-Emphysema (COPD-E) Study

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha1-antitrypsin Deficiency
Shire
Testing effectiveness (Phase 2)Ended earlyNCT01379469
What this trial is testing

Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1-antitrypsin DeficiencyLiver Cirrhosis
Washington University School of Medicine 20
Testing effectiveness (Phase 2)Study completedNCT01684410
What this trial is testing

Safety and Tolerability Trial of Inhaled Alpha1-Proteinase Inhibitor (Human), Hydrophobic Chromatography Process (Alpha-1 HC) in Subjects With Cystic Fibrosis

Who this might be right for
Cystic Fibrosis
Grifols Therapeutics LLC 30
Early research (Phase 1)Looking for participantsNCT07431112
What this trial is testing

AIR-001 in Adults With Alpha-1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha 1 Antitrypsin Deficiency
AIRNA Corporation 54
Not applicableUnknownNCT04966221
What this trial is testing

Functional and Structural Lung Imaging in Chronic Obstructive Pulmonary Disease

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha 1-Antitrypsin Deficiency
University of Nottingham 75
Not applicableUnknownNCT02929940
What this trial is testing

Liver Disease in Patients With alpha1-antitrypsin Deficiency

Who this might be right for
alpha1-antitrypsin Deficiency
RWTH Aachen University 500
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