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Results for “Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT00460096
What this trial is testing

Phase II/III Study of an Alpha-1 Proteinase Inhibitor (Kamada-API) in Individuals With Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Kamada, Ltd. 50
Testing effectiveness (Phase 2)Study completedNCT00263887
What this trial is testing

Alpha-1-Antitrypsin (AAT) To Treat Emphysema In AAT-Deficient Patients (EXACTLE)

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Grifols Therapeutics LLC 77
Large-scale testing (Phase 3)Ended earlyNCT04204252
What this trial is testing

Phase III, Efficacy and Safety of "Kamada-AAT for Inhalation"

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Kamada, Ltd. 98
Testing effectiveness (Phase 2)Study completedNCT03946449
What this trial is testing

Study of Fazirsiran (TAK-999, ARO-AAT) in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATD)

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Arrowhead Pharmaceuticals 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT05897424
What this trial is testing

Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema

Who this might be right for
Alpha 1-Antitrypsin DeficiencyEmphysema
Sanofi 185
Testing effectiveness (Phase 2)Study completedNCT03945292
What this trial is testing

Safety, Tolerability and Pharmacodynamic Effect of Fazirsiran (TAK-999, ARO-AAT)

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Arrowhead Pharmaceuticals 40
Not applicableStudy completedNCT03470857
What this trial is testing

Oxidoreductive Balance and Lysosomal Activity in Cancer Patients.

Who this might be right for
NeoplasmsAntioxidantsOxidative Stress+3 more
Nicolaus Copernicus University 83
Testing effectiveness (Phase 2)WithdrawnNCT01183455
What this trial is testing

A Research Trial of Aralast NP in New Onset Diabetes (RETAIN) - Part II

Who this might be right for
Diabetes Mellitus, Type 1
National Institute of Allergy and Infectious Diseases (NIAID)
Not applicableStudy completedNCT01380626
What this trial is testing

Effects of Exercise Training in Chronic Obstructive Pulmonary Disease Versus Alpha-1-Antitrypsin-deficiency-patients

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha-1-antitrypsin-deficiency
Schön Klinik Berchtesgadener Land 20
Not applicableLooking for participantsNCT07152834
What this trial is testing

Screening for Alpha-1 Antitrypsin Deficiency in Patients With Airway Obstruction

Who this might be right for
Alpha 1-antitrypsin Deficiency (AATD)
Muğla Sıtkı Koçman University 734
Post-approval studies (Phase 4)WithdrawnNCT05466747
What this trial is testing

RYMPHYSIA for Alpha1-Proteinase Inhibitor (A1PI) Therapy in Adults With A1PI Deficiency and Chronic Obstructive Pulmonary Disease (COPD)-Emphysema

Who this might be right for
Chronic Obstructive Pulmonary Disease (COPD)Alpha1-Antitrypsin Deficiency
Takeda
Testing effectiveness (Phase 2)Active Not RecruitingNCT06405633
What this trial is testing

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Wave Life Sciences USA, Inc. 24
Testing effectiveness (Phase 2)Study completedNCT01213043
What this trial is testing

Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin Deficiency

Who this might be right for
EmphysemaAlpha 1-antitrypsin Deficiency (AATD)
Grifols Therapeutics LLC 30
Not applicableUnknownNCT05622838
What this trial is testing

Maternal alpha1 Antitrypsin as a Marker of Intrauterine Growth Restriction in Pre-eclamptic Women

Who this might be right for
alpha1 Anti-trypsinPre-EclampsiaIntrauterine Growth Restriction
Assiut University 160
Testing effectiveness (Phase 2)Study completedNCT03679598
What this trial is testing

Alvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin Deficiency

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)Pi*ZZ, Pi*SZ, Pi*Null, Another Rare Phenotype/Genotype Known to be Associated With Either Low or Functionally Impaired AAT Including F or I MutationsEmphysema or COPD
University of Alabama at Birmingham 63
Large-scale testing (Phase 3)Study completedNCT01217671
What this trial is testing

International Study Evaluating the Safety and Efficacy of Inhaled, Human, Alpha-1 Antitrypsin (AAT) in Alpha-1 Antitrypsin Deficient Patients With Emphysema

Who this might be right for
Emphysema
Kamada, Ltd. 168
Testing effectiveness (Phase 2)Study completedNCT01669421
What this trial is testing

Effect of Double Dose of Alpha 1-antitrypsin Augmentation Therapy on Lung Inflammation.

Who this might be right for
Alpha 1 Antitrypsin Deficiency
Michael Campos, MD 10
Testing effectiveness (Phase 2)Study completedNCT02870348
What this trial is testing

Long-term Safety of Alpha1-Proteinase Inhibitor (Human) in Japanese Subjects With Alpha1 Antitrypsin Deficiency (GTI1401-OLE)

Who this might be right for
Alpha1-Antitrypsin Deficiency
Grifols Therapeutics LLC 4
Testing effectiveness (Phase 2)Study completedNCT03636347
What this trial is testing

A 12-week Study Treating Participants Who Have alpha1-antitrypsin-related COPD With Alvelestat (MPH966) or Placebo.

Who this might be right for
Alpha 1-Antitrypsin DeficiencyEmphysemaCOPD
Mereo BioPharma 99
Testing effectiveness (Phase 2)Study completedNCT00161707
What this trial is testing

Safety Study of an Aerosolized, Recombinant Alpha 1-Antitrypsin in Subjects With Alpha 1-Antitrypsin Deficiency

Who this might be right for
Alpha1-antitrypsin Deficiency
Baxalta now part of Shire 40
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