Testing effectiveness (Phase 2)Study completedNCT00759408What this trial is testingThe Role of Endothelin in Pulmonary HypertensionWho this might be right forPulmonary Hypertension Brigham and Women's Hospital 38
Large-scale testing (Phase 3)Ended earlyNCT00458276What this trial is testingStudy of the Efficacy and Safety of Tezosentan in Patients With Pre-operative Pulmonary Hypertension, Due to Left Heart Disease, Undergoing Open Heart SurgeryWho this might be right forHeart DiseasesHypertension, Pulmonary Idorsia Pharmaceuticals Ltd. 274
Early research (Phase 1)Study completedNCT06048120What this trial is testingLearn How Safe the Study Treatment BAY2701250 is, How it Affects the Body and How it Moves Into, Through and Out of the Body in Healthy Male Participants When a Single Amount is Given as an Injection Into the Vein (Intravenous Infusion) or Under the Skin (Subcutaneous Injection)Who this might be right forPulmonary Hypertension Due to Left Heart Disease Bayer 82
Not applicableNot Yet RecruitingNCT05464238What this trial is testingTraining in HFpEF-PHWho this might be right forPulmonary Hypertension Due to Left Heart DiseaseHeart Failure With Preserved Ejection Fraction Heidelberg University 90
Not applicableLooking for participantsNCT07537517What this trial is testingEvaluation of the BMPR2-Activin Signaling Pathway in Group II Pulmonary Hypertension.Who this might be right forPulmonary Hypertension Due to Left Heart DiseasePulmonary Hypertension (PH)Heart Failure Hospital General Universitario Gregorio Marañon 150
Testing effectiveness (Phase 2)Study completedNCT05737940What this trial is testingAZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2Who this might be right forPulmonary Hypertension (World Health Organization Group 2)Heart Failure AstraZeneca 260
Not applicableActive Not RecruitingNCT03611270What this trial is testingTReatment of Pulmonary Hypertension Group II StudyWho this might be right forPulmonary Hypertension (PH) Due to Left Heart Disease SoniVie Inc. 15
Not applicableLooking for participantsNCT04808596What this trial is testingPulmonary Hypertension Biorepository and RegistryWho this might be right forPulmonary HypertensionPulmonary Arterial HypertensionPulmonary Hypertension Due to Left Heart Disease+6 more University of Kansas Medical Center 300
Not applicableLooking for participantsNCT07214376What this trial is testingPlacebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart DiseaseWho this might be right forPulmonary HypertensionHeart Failure With Reduced Ejection FractionHypertension+5 more Pulnovo Medical, Inc. 750
Not applicableUnknownNCT02164526What this trial is testingRegistry for Pulmonary Hypertension Due to Left Heart Disease in ChinaWho this might be right forPulmonary Hypertension Due to Left Heart Disease Chinese Academy of Medical Sciences, Fuwai Hospital 520
Large-scale testing (Phase 3)Active Not RecruitingNCT05824923What this trial is testingA Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart FailureWho this might be right forPulmonary HypertensionHeart Failure With Reduced Ejection FractionHypertension+5 more Pulnovo Medical (Wuxi) Co., Ltd. 264
Post-approval studies (Phase 4)Looking for participantsNCT04484675What this trial is testingInhaled and Intravenous Milrinone in Patients With Severe Pulmonary HypertensionWho this might be right forPulmonary Hypertension Due to Left Heart Disease Zagazig University 38
Testing effectiveness (Phase 2)WithdrawnNCT04882774What this trial is testingTelemonitoring to Treat Group 2 Pulmonary HypertensionWho this might be right forPulmonary Hypertension Due to Left Heart Disease Mardi Gomberg -Maitland MD, MSc
Not applicableLooking for participantsNCT06299436What this trial is testingHemodynamic Assessment of underLying myocyTe Function in Right Heart FailureWho this might be right forHeart Failure With Reduced Ejection FractionPulmonary HypertensionRight Heart Failure Due to Left Heart Failure Johns Hopkins University 50