Early research (Phase 1)Ended earlyNCT04800822What this trial is testingPF-07284892 in Participants With Advanced Solid TumorsWho this might be right forSolid Tumor Pfizer 53
Large-scale testing (Phase 3)Looking for participantsNCT07491445What this trial is testingStudy of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic AdenocarcinomaWho this might be right forPancreatic CancerPancreatic Cancer MetastaticPDAC+5 more Revolution Medicines, Inc. 900
Testing effectiveness (Phase 2)Study completedNCT05340621What this trial is testingNAUTILUS: OKI-179 Plus Binimetinib in Patients with Advanced Solid Tumors in the RAS Pathway (Phase 1b) and NRAS-mutated Melanoma (Phase 2)Who this might be right forRAS MutationNRAS Gene MutationMelanoma OnKure, Inc. 36
Testing effectiveness (Phase 2)UnknownNCT06206096What this trial is testingPD-1 Antibody Plus Bevacizumab and CAPOX as First-line Treatment for RAS-mut MSS mCRCWho this might be right forColorectal CancerRAS MutationColorectal Neoplasms+1 more Chinese PLA General Hospital 40
Not applicableUnknownNCT02502656What this trial is testingRAS Mutation Testing in the Circulating Blood of Patients With Metastatic Colorectal CancerWho this might be right forColorectal Cancer Association des Gastroentérologues Oncologues 425
Testing effectiveness (Phase 2)Looking for participantsNCT06922591What this trial is testingStudy to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC PatientsWho this might be right forPDACPDAC - Pancreatic Ductal AdenocarcinomaNSCLC+5 more Tango Therapeutics, Inc. 183
Testing effectiveness (Phase 2)UnknownNCT05640726What this trial is testingThe First-line Treatment of RCLM With RAS Mutation Was Local Short-course Radiotherapy (SCRT) + PD-1+ Standard TherapyWho this might be right forRectal Cancer Fujian Cancer Hospital 30
Early research (Phase 1)Study completedNCT03317119What this trial is testingTrametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by SurgeryWho this might be right forMetastatic Colon CarcinomaMetastatic Colorectal CarcinomaMetastatic Rectal Carcinoma+22 more City of Hope Medical Center 26
Testing effectiveness (Phase 2)Study completedNCT02350530What this trial is testingFOLFOXIRI With or Without Bevacizumab as First-line Treatment for Unresectable Liver-only Metastatic Colorectal Cancer Patients With RAS Mutation-typeWho this might be right forMetastatic Colorectal Cancer Sun Yat-sen University 138
Early research (Phase 1)Looking for participantsNCT06884618What this trial is testingEvaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)Who this might be right forNeoplasms Hoffmann-La Roche 405
Large-scale testing (Phase 3)Looking for participantsNCT07252232What this trial is testingStudy of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)Who this might be right forPancreatic CancerPDACPDAC - Pancreatic Ductal Adenocarcinoma+2 more Revolution Medicines, Inc. 500
Testing effectiveness (Phase 2)Looking for participantsNCT06895031What this trial is testingStudy of JYP0015 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RASWho this might be right forSolid TumorPancreatic Ductal Adenocarcinoma (PDAC)Non-small Cell Lung Cancer (NSCLC)+1 more Guangzhou JOYO Pharma Co., Ltd 210
Testing effectiveness (Phase 2)Study completedNCT01927341What this trial is testingPhase Ib/II Study of Efficacy and Safety of MEK162 and Panitumumab, in Adult mCRC Patients With Mutant or Wild-type RAS TumorsWho this might be right forMetastatic Colorectal Cancer Pfizer 53
Testing effectiveness (Phase 2)Ended earlyNCT01085331What this trial is testingMEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC)Who this might be right forMetastatic Colorectal Cancer EMD Serono 16
Early research (Phase 1)Looking for participantsNCT04678648What this trial is testingA Trial of RSC-1255 for Treatment of Patients With Advanced MalignanciesWho this might be right forAdvanced Malignant Solid NeoplasmRAS MutationLung Cancer+3 more RasCal Therapeutics, Inc. 134
Testing effectiveness (Phase 2)Looking for participantsNCT06445062What this trial is testingStudy of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid TumorsWho this might be right forColorectal CancerCRCPancreatic Ductal Adenocarcinoma+3 more Revolution Medicines, Inc. 1,130
Testing effectiveness (Phase 2)Looking for participantsNCT06229340What this trial is testingLeflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS MutationsWho this might be right forRAS MutationRas (Kras or Nras) Gene MutationColorectal Cancer Recurrent+4 more N.N. Petrov National Medical Research Center of Oncology 20
Testing effectiveness (Phase 2)Study completedNCT03271047What this trial is testingStudy of Binimetinib + Nivolumab Plus or Minus Ipilimumab in Patients With Previously Treated Microsatellite-stable (MSS) Metastatic Colorectal Cancer With RAS MutationWho this might be right forMSSRAS-mutant Colorectal Cancer Pfizer 75
Testing effectiveness (Phase 2)Study completedNCT00989469What this trial is testingSorafenib With Irinotecan in Metastatic Colorectal Cancer (mCRC) and K-RAS MutationWho this might be right forMetastatic Colorectal Cancer Institut du Cancer de Montpellier - Val d'Aurelle 64
Large-scale testing (Phase 3)Looking for participantsNCT04776655What this trial is testingStudy in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaBWho this might be right forColorectal CancerMetastatic Colorectal CancerRAS Mutation Azienda USL Reggio Emilia - IRCCS 280