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Results for “RAS Mutation”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Looking for participantsNCT07805954
What this trial is testing

Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma

Who this might be right for
Pancreatic CancerPancreatic Cancer MetastaticPDAC+5 more
Revolution Medicines, Inc. 400
Testing effectiveness (Phase 2)UnknownNCT04310176
What this trial is testing

Valproic Acid in Combination With Bevacizumab and Oxaliplatin/Fluoropyrimidine Regimens in Patients With Ras-mutated Metastatic Colorectal Cancer

Who this might be right for
Ras-mutated Metastatic Colorectal Cancer
National Cancer Institute, Naples 200
Testing effectiveness (Phase 2)Looking for participantsNCT06922591
What this trial is testing

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

Who this might be right for
PDACPDAC - Pancreatic Ductal AdenocarcinomaNSCLC+5 more
Tango Therapeutics, Inc. 183
Testing effectiveness (Phase 2)Study completedNCT00300950
What this trial is testing

Safety and Efficacy of the Therapeutic Vaccine GI-4000 in Combination With Gemcitabine Versus Placebo for the Treatment of Non-metastatic, Post-resection Pancreas Cancer

Who this might be right for
Pancreas Cancer
GlobeImmune 176
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07622550
What this trial is testing

A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Serplulimab and Chemotherapy as First-line Treatment for Patients With RAS/BRAF-mutated Advanced Colorectal Cance

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Jiangsu Cancer Institute & Hospital 80
Testing effectiveness (Phase 2)Study completedNCT01116271
What this trial is testing

Study of Selumetinib (AZD6244)(ARRY-142886) in Combination With Irinotecan in Previously Treated Patients With Colorec

Who this might be right for
Colorectal Cancer
AstraZeneca 32
Testing effectiveness (Phase 2)Study completedNCT01086267
What this trial is testing

Safety and Efficacy Study of BMS-908662 Alone or in Combination With Cetuximab in Subjects With K-RAS or B-RAF Mutation Positive Advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Bristol-Myers Squibb 17
Large-scale testing (Phase 3)Looking for participantsNCT07621718
What this trial is testing

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

Who this might be right for
Pancreatic CancerPancreatic Cancer MetastaticPDAC+5 more
Revolution Medicines, Inc. 670
Early research (Phase 1)Study completedNCT04853017
What this trial is testing

ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors

Who this might be right for
Minimal Residual DiseaseKRAS G12DKRAS G12R+9 more
Elicio Therapeutics 25
Testing effectiveness (Phase 2)Looking for participantsNCT06229340
What this trial is testing

Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations

Who this might be right for
RAS MutationRas (Kras or Nras) Gene MutationColorectal Cancer Recurrent+4 more
N.N. Petrov National Medical Research Center of Oncology 20
Testing effectiveness (Phase 2)UnknownNCT05634590
What this trial is testing

The Efficacy and Safety of Fruquintinib Plus FOLFIRI/FOLFOX as Second-line Treatment in Patients With RAS-mutant Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Fudan University 68
Large-scale testing (Phase 3)Active Not RecruitingNCT04776655
What this trial is testing

Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB

Who this might be right for
Colorectal CancerMetastatic Colorectal CancerRAS Mutation
Azienda USL Reggio Emilia - IRCCS 280
Testing effectiveness (Phase 2)Study completedNCT00869570
What this trial is testing

External-Beam Radiation Therapy, Capecitabine, and Sorafenib in Treating Patients With Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer
Swiss Cancer Institute 54
Testing effectiveness (Phase 2)Ended earlyNCT03705507
What this trial is testing

International Trial of Selumetinib in Combination With Dexamethasone for the Treatment of Acute Lymphoblastic Leukaemia

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Lymphoblastic Leukemia, AdultAcute Lymphoblastic Leukemia, Pediatric+2 more
University of Birmingham 12
Testing effectiveness (Phase 2)Study completedNCT00019331
What this trial is testing

Vaccine Therapy Plus Biological Therapy in Treating Adults With Metastatic Solid Tumors

Who this might be right for
Colorectal CancerEndometrial CancerHead and Neck Cancer+6 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT06949982
What this trial is testing

Efficacy And Safety Of Hydroxychloroquine Combined With Methotrexate, Capecitabine And Bevacizumab Vs. Regorafenib In Participants With Refractory Metastatic Colorectal Cancer With Mutations In RAS Genes

Who this might be right for
Metastatic Colorectal Cancer (mCRC)Colorectal Neoplasms
Sergey Orlov, MD 60
Early research (Phase 1)Study completedNCT05441514
What this trial is testing

Enasidenib in Combination With Cobimetinib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia
City of Hope Medical Center 3
Testing effectiveness (Phase 2)Study completedNCT05068752
What this trial is testing

Phase II Trial of Vemurafenib and Sorafenib in Pancreatic Cancer

Who this might be right for
Pancreas Cancer
HonorHealth Research Institute 10
Testing effectiveness (Phase 2)Looking for participantsNCT06445062
What this trial is testing

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Who this might be right for
Colorectal CancerCRCPancreatic Ductal Adenocarcinoma+3 more
Revolution Medicines, Inc. 1,130
Testing effectiveness (Phase 2)Study completedNCT02350530
What this trial is testing

FOLFOXIRI With or Without Bevacizumab as First-line Treatment for Unresectable Liver-only Metastatic Colorectal Cancer Patients With RAS Mutation-type

Who this might be right for
Metastatic Colorectal Cancer
Sun Yat-sen University 138
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