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Results for “RAS Mutation”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07797244
What this trial is testing

A Single-Arm, Phase II Study of Retlirafusp Alfa in Combination With XELOX and Bevacizumab for the First-Line Treatment of Advanced RAS-Mutated Colorectal Cancer With Liver Metastases (CRLM)

Who this might be right for
Advanced RAS-Mutated Colorectal Cancer With Liver Metastases (CRLM)
Dai, Guanghai 46
Not applicableLooking for participantsNCT04395495
What this trial is testing

RASopathy Biorepository

Who this might be right for
RAS MutationNeurofibromatosis 1Noonan Syndrome+11 more
Children's Hospital Medical Center, Cincinnati 1,000
Early research (Phase 1)Looking for participantsNCT04678648
What this trial is testing

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

Who this might be right for
Advanced Malignant Solid NeoplasmRAS MutationLung Cancer+3 more
RasCal Therapeutics, Inc. 134
Large-scale testing (Phase 3)Active Not RecruitingNCT04793958
What this trial is testing

Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10)

Who this might be right for
Advanced Colorectal CancerMetastatic Colorectal Cancer
Mirati Therapeutics Inc. 461
Early research (Phase 1)Looking for participantsNCT06884618
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)

Who this might be right for
Neoplasms
Hoffmann-La Roche 405
Testing effectiveness (Phase 2)UnknownNCT04775862
What this trial is testing

A Prospective Study Utilizing Circulating Cell Free DNA (cfDNA) Use in the Detection of RAS Mutations in Patients With Advanced Colorectal Cancer.

Who this might be right for
Colon Cancer
National Guard Health Affairs 60
Early research (Phase 1)Ended earlyNCT07121829
What this trial is testing

Tovorafenib (DAY101) or in Combination With Pimasertib for Participants With Melanoma and Other Solid Tumors

Who this might be right for
MelanomaSolid TumorPilocytic Astrocytoma+7 more
Day One Biopharmaceuticals, Inc. 44
Testing effectiveness (Phase 2)Looking for participantsNCT07020221
What this trial is testing

VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

Who this might be right for
Pancreatic Ductal AdenocarcinomaNon Small Cell Lung CancerColorectal Cancer+2 more
Verastem, Inc. 295
Testing effectiveness (Phase 2)Looking for participantsNCT06321081
What this trial is testing

ICE Study: Combination of Irinotecan Plus Cetuximab and Envafolimab as a Rechallenge Regimen in mCRC

Who this might be right for
RAS MutationMetastatic Colorectal CancerMSS
Beijing Hospital 60
Not applicableStudy completedNCT00898924
What this trial is testing

Epidermal Growth Factor Receptor and K-ras Mutations in Patients With Stage III Non-Small Cell Lung Cancer

Who this might be right for
Lung Cancer
Alliance for Clinical Trials in Oncology 60
Large-scale testing (Phase 3)Looking for participantsNCT06226857
What this trial is testing

Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer

Who this might be right for
Colorectal NeoplasmsChemotherapy EffectMolecular Sequence Variation
City Clinical Oncology Hospital No 1 355
Testing effectiveness (Phase 2)Study completedNCT03244956
What this trial is testing

Efficacy of MEK (Trametinib) and BRAFV600E (Dabrafenib) Inhibitors With Radioactive Iodine (RAI) for the Treatment of Refractory Metastatic Differentiated Thyroid Cancer

Who this might be right for
Metastatic Radioactive Iodine Refractory Thyroid Cancer Patients With RAS or BRAF Mutation
Gustave Roussy, Cancer Campus, Grand Paris 40
Testing effectiveness (Phase 2)Ended earlyNCT01085331
What this trial is testing

MEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC)

Who this might be right for
Metastatic Colorectal Cancer
EMD Serono 16
Testing effectiveness (Phase 2)Study completedNCT00019084
What this trial is testing

Vaccine Therapy and Biological Therapy in Treating Patients With Advanced Cancer

Who this might be right for
Breast CancerCervical CancerColorectal Cancer+3 more
National Cancer Institute (NCI)
Large-scale testing (Phase 3)Looking for participantsNCT07777822
What this trial is testing

Study of Pembrolizumab + Pemetrexed + Platinum Chemotherapy With or Without Zoldonrasib as First Line Treatment in Metastatic Non-squamous RAS G12D-Mutated NSCLC

Who this might be right for
NSCLCNon-small Cell Lung CancerNon-Small Cell Lung Cancer NSCLC+4 more
Revolution Medicines, Inc. 430
Early research (Phase 1)Ended earlyNCT04800822
What this trial is testing

PF-07284892 in Participants With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Pfizer 53
Not applicableActive Not RecruitingNCT03908788
What this trial is testing

Detection of the Emergence of RAS (Rat Sarcoma Viral Oncogene Homolog) Mutations in Circulating DNA (Deoxyribonucleic Acid) in Patients With mCRC (Metastatic Colorectal Cancer) During Treatment With Anti-EGFR (Epidermal Growth Factor Receptor) Therapy

Who this might be right for
Metastatic Colorectal Cancer
Institut du Cancer de Montpellier - Val d'Aurelle 130
Testing effectiveness (Phase 2)Study completedNCT00019591
What this trial is testing

Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)UnknownNCT06206096
What this trial is testing

PD-1 Antibody Plus Bevacizumab and CAPOX as First-line Treatment for RAS-mut MSS mCRC

Who this might be right for
Colorectal CancerRAS MutationColorectal Neoplasms+1 more
Chinese PLA General Hospital 40
Early research (Phase 1)Active Not RecruitingNCT05907304
What this trial is testing

Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

Who this might be right for
Advanced or Metastatic Solid Tumors
Erasca, Inc. 86
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