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Results for “RAS Wild-type”

154 trials

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Showing 20 of 154 results

Testing effectiveness (Phase 2)WithdrawnNCT03069950
What this trial is testing

Study of Chemotherapy With or Without Hepatic Arterial Infusion for Patients With Unresectable Metastatic Colorectal Cancer to the Liver

Who this might be right for
Colorectal Adenocarcinoma Metastatic to the Liver
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)UnknownNCT02904031
What this trial is testing

Study of I Line FOLFOX + Panitumumab vs 5FU + Panitumumab in RAS and BRAF WT Metastatic Colorectal Cancer Elderly Patients

Who this might be right for
Elderly Metastatic Colorectal Cancer Patients
Gruppo Oncologico del Nord-Ovest 180
Early research (Phase 1)Study completedNCT03317119
What this trial is testing

Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery

Who this might be right for
Metastatic Colon CarcinomaMetastatic Colorectal CarcinomaMetastatic Rectal Carcinoma+22 more
City of Hope Medical Center 26
Large-scale testing (Phase 3)UnknownNCT01910610
What this trial is testing

Multi-Line Therapy Trial in Unresectable Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
GERCOR - Multidisciplinary Oncology Cooperative Group 464
Large-scale testing (Phase 3)Looking for participantsNCT06280495
What this trial is testing

Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients

Who this might be right for
Colorectal CancerLiver Metastases
Sun Yat-sen University 156
Testing effectiveness (Phase 2)UnknownNCT00972465
What this trial is testing

Study of Nimotuzumab to Treat Colorectal Cancer

Who this might be right for
Advanced Colorectal Cancer
Peking University 48
Not applicableUnknownNCT03263663
What this trial is testing

Optimization of Individualized Therapy for CRCs With Secondary RESISTance Towards Anti-EGFR Targeted Therapy Using an Avatar Model

Who this might be right for
Colo-rectal CancerRAS Wild-typeUICC III+2 more
PD Dr. med. Volker Heinemann 1,000
Not applicableStudy completedNCT04466267
What this trial is testing

The Molecular Mechanism of RAS Wild-type mCRC Resistance to Anti-EGFR-antibody

Who this might be right for
Colorectal Cancer
Sun Yat-sen University 40
Testing effectiveness (Phase 2)Study completedNCT03142516
What this trial is testing

FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status

Who this might be right for
Colorectal NeoplasmsColorectal CarcinomaColorectal Cancer Metastatic+1 more
Grupo Espanol Multidisciplinario del Cancer Digestivo 20
Testing effectiveness (Phase 2)Study completedNCT00594984
What this trial is testing

Phase I/II Combination With Irinotecan- Erbitux

Who this might be right for
Metastatic Colorectal Cancer (MCRC)
Bristol-Myers Squibb 38
Testing effectiveness (Phase 2)Study completedNCT01640444
What this trial is testing

Influence of BRAF and PIK3K Status on the Efficacy of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFIRI) Plus Bevacizumab or Cetuximab in Patients With RAS Wild-type Metastatic Colorectal Carcinoma and < 3 Circulating Tumor Cells (CTC)

Who this might be right for
Colorectal Cancer Metastatic
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) 240
Not applicableActive Not RecruitingNCT02394834
What this trial is testing

An Exploratory Study of Treatment Sensitivity and Prognostic Factors in a Efficacy and Safety Study of mFOLFOX6 + Bevacizumab Versus mFOLFOX6 + Panitumumab Therapy in Patients With Chemotherapy-naïve Unresectable Advanced or Recurrent Colorectal Cancer

Who this might be right for
Colorectal Cancer
Takeda 757
Large-scale testing (Phase 3)Study completedNCT02484833
What this trial is testing

Erbitux MEtastatic Colorectal Cancer Strategy Study

Who this might be right for
Antineoplastic Agents
Armando Orlandi 607
Early research (Phase 1)Study completedNCT03714958
What this trial is testing

Trametinib + HDM201 in CRC Patients With RAS/RAF Mutant and TP53 Wild-type Advanced/Metastatic Colorectal Cancer Mutant and TP53 Wild-type

Who this might be right for
Colorectal CancerAdvanced CancerMetastatic Cancer
Centre Leon Berard 12
Testing effectiveness (Phase 2)Study completedNCT02292758
What this trial is testing

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With RAS Wild-Type Locally Advanced or Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Who this might be right for
Colorectal AdenocarcinomaRAS Wild TypeStage IV Colorectal Cancer AJCC v7+2 more
Academic and Community Cancer Research United 36
Testing effectiveness (Phase 2)Looking for participantsNCT05694936
What this trial is testing

Combining Sodium Valproate With Standard-of-care EGFR (Epidermal Growth Factor Receptor) Monoclonal Antibody Treatment in Patients With Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Australasian Gastro-Intestinal Trials Group 90
Testing effectiveness (Phase 2)UnknownNCT03405272
What this trial is testing

Safety and Efficacy of Recombinant Anti-EGFR Monoclonal Antibody in Patients With Wild-type RAS and BRAF mCRC

Who this might be right for
Metastatic Colorectal Cancer
Sinocelltech Ltd. 110
Testing effectiveness (Phase 2)Study completedNCT01836653
What this trial is testing

Achievement of Improved Survival by Molecular Targeted Chemotherapy and Liver Resection for Not Optimally Resectable Colorectal Liver Metastases

Who this might be right for
Liver Only Metastasis From KRAS Exon 2 Wild Type (Under Protocol 1.0-1.2 Edition) and RAS Wild Type (Under Protocol 2.0 Edition) Colorectal Cancer
EPS Corporation 122
Large-scale testing (Phase 3)Ended earlyNCT03300609
What this trial is testing

5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumab

Who this might be right for
Colorectal AdenocarcinomaRAS Wild TypeStage III Colorectal Cancer AJCC v7+6 more
University of Southern California 4
Testing effectiveness (Phase 2)Study completedNCT00640081
What this trial is testing

Combination Chemotherapy and Cetuximab as First-Line Therapy in Treating Patients With Advanced and/or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Cheryl Pugh 169
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