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Results for “RAS and BRAF Wild-type”

36 trials

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Showing 20 of 36 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05312398
What this trial is testing

CAPRI 2 GOIM Study: Investigate the Efficacy and Safety of a Bio-marker Driven Cetuximab-based Treatment Regimen

Who this might be right for
Metastatic Colorectal Adenocarcinoma
University of Campania Luigi Vanvitelli 219
Large-scale testing (Phase 3)UnknownNCT04262635
What this trial is testing

Cetuximab Plus Capecitabine as Maintenance Treatment in RAS and BRAF wt Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Sun Yat-sen University 80
Large-scale testing (Phase 3)Looking for participantsNCT06280495
What this trial is testing

Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients

Who this might be right for
Colorectal CancerLiver Metastases
Sun Yat-sen University 156
Testing effectiveness (Phase 2)Looking for participantsNCT07257653
What this trial is testing

The Safety and Efficacy of Cetuximab Beta Plus Fruquintinib With or Without Immune Checkpoint Inhibitorrs in First-line Treatment of RAS/BRAF Wild Type Unresectable Metastatic Colorectal Cancer

Who this might be right for
Colorectal NeoplasmsRASBRAF+2 more
Zhejiang University 70
Large-scale testing (Phase 3)Study completedNCT03231722
What this trial is testing

First Line mFOLFOXIRI + PANITUMUMAB vs mFOLFOX + PANITUMUMAB IN RAS AND BRAF WT METASTATIC COLORECTAL CANCER PATIENTS

Who this might be right for
Metastatic Colorectal Cancer
Gruppo Oncologico del Nord-Ovest 435
Testing effectiveness (Phase 2)Looking for participantsNCT06714357
What this trial is testing

ValproIc Acid to Potentiate Anti-EGFR Treatment Efficacy and Prevent/Revert Resistance in Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
National Cancer Institute, Naples 130
Testing effectiveness (Phase 2)Looking for participantsNCT06908031
What this trial is testing

SCRT + mFOLFOX6 + PD-1 Antibody + Targeted Therapy for HIgh-Risk pMMR/MSS Rectal Cancer

Who this might be right for
Rectal AdenocarcinomaHigh-Risk CancerMSS
Sixth Affiliated Hospital, Sun Yat-sen University 49
Large-scale testing (Phase 3)Looking for participantsNCT04776655
What this trial is testing

Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB

Who this might be right for
Colorectal CancerMetastatic Colorectal CancerRAS Mutation
Azienda USL Reggio Emilia - IRCCS 280
Testing effectiveness (Phase 2)Active Not RecruitingNCT04787341
What this trial is testing

PAnitumumab REchallenge Followed by REgorafenib Versus the Reverse Sequence

Who this might be right for
Colorectal Cancer
Gruppo Oncologico del Nord-Ovest 214
Testing effectiveness (Phase 2)UnknownNCT02904031
What this trial is testing

Study of I Line FOLFOX + Panitumumab vs 5FU + Panitumumab in RAS and BRAF WT Metastatic Colorectal Cancer Elderly Patients

Who this might be right for
Elderly Metastatic Colorectal Cancer Patients
Gruppo Oncologico del Nord-Ovest 180
Testing effectiveness (Phase 2)Looking for participantsNCT05742425
What this trial is testing

Serplulimab Combined With FOLFIRI and Bevacizumab in the Treatment of Colon Cancer Peritoneal Metastases

Who this might be right for
Unresectable Colon Cancer Peritoneal MetastasesPMMR/Ras/BRAF Wild-type
Second Affiliated Hospital, School of Medicine, Zhejiang University 30
Testing effectiveness (Phase 2)Ended earlyNCT02508077
What this trial is testing

FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer

Who this might be right for
Recurrent Colorectal CarcinomaStage IVA Colorectal CancerStage IVB Colorectal Cancer
City of Hope Medical Center 1
Testing effectiveness (Phase 2)Study completedNCT01358812
What this trial is testing

FOLFOXIRI Plus Panitumumab In Kras and Braf Wild-Type Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colo-rectal Cancer
Gruppo Oncologico del Nord-Ovest 37
Testing effectiveness (Phase 2)UnknownNCT06231017
What this trial is testing

Adebrelimab Plus Cetuximab and Chemotherapy for Patients With RAS/BRAF Wild-Type Unresectable Liver Metastases Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
The First Affiliated Hospital of Zhengzhou University 36
Testing effectiveness (Phase 2)Study completedNCT01640444
What this trial is testing

Influence of BRAF and PIK3K Status on the Efficacy of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFIRI) Plus Bevacizumab or Cetuximab in Patients With RAS Wild-type Metastatic Colorectal Carcinoma and < 3 Circulating Tumor Cells (CTC)

Who this might be right for
Colorectal Cancer Metastatic
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) 240
Testing effectiveness (Phase 2)Study completedNCT02399943
What this trial is testing

A Trial of Trametinib and Panitumumab in RAS/RAF Wild Type Advanced Colorectal Cancer

Who this might be right for
Colorectal CancerKRAS WildtypeNRAS Wildtype+1 more
University Health Network, Toronto 14
Testing effectiveness (Phase 2)UnknownNCT03405272
What this trial is testing

Safety and Efficacy of Recombinant Anti-EGFR Monoclonal Antibody in Patients With Wild-type RAS and BRAF mCRC

Who this might be right for
Metastatic Colorectal Cancer
Sinocelltech Ltd. 110
Testing effectiveness (Phase 2)UnknownNCT05468177
What this trial is testing

Cetuximab in Combination With Anti-PD-1 and mFOLFOX Treat For RAS/BRAF wt Right-Sided Colon Cancer

Who this might be right for
Colonic Neoplasms
Tongji Hospital 66
Large-scale testing (Phase 3)UnknownNCT05074966
What this trial is testing

The Efficacy and Safety of Modified XELOX(mXELOX) Plus Cetuximab vs FOLFOX Plus Cetuximab in RAS and BRAF WT mCRC Pts

Who this might be right for
Colo-rectal Cancer
Chinese Academy of Medical Sciences 314
Testing effectiveness (Phase 2)Looking for participantsNCT05959356
What this trial is testing

Cetuximab and Envafolimab Plus mFOLFOXIRI as First-line Treatment for RAS/BRAF Wild-type, MSS, Unresectable Left-side Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Sun Yat-sen University 198
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