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Results for “RAS and BRAF Wild-type”

41 trials

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Showing 20 of 41 results

Large-scale testing (Phase 3)UnknownNCT05948072
What this trial is testing

Cetuximab+mFOLFOX6 VS. mFOLFOX6 Alone in RAS/BRAF Wild Type Patients With High-Risk Resectable CRLM

Who this might be right for
Colorectal CancerLiver Metastases
Fudan University 250
Testing effectiveness (Phase 2)UnknownNCT06379399
What this trial is testing

Trifluridine/Tipiracil Combined With Cetuximab in the Treatment of Third-line and Above RAS/BRAF Wild-type mCRC

Who this might be right for
Colorectal Cancer Metastatic
Wangxia LV 26
Large-scale testing (Phase 3)Active Not RecruitingNCT04776655
What this trial is testing

Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB

Who this might be right for
Colorectal CancerMetastatic Colorectal CancerRAS Mutation
Azienda USL Reggio Emilia - IRCCS 280
Large-scale testing (Phase 3)Looking for participantsNCT07702032
What this trial is testing

Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer (LiGeR-CRC1)

Who this might be right for
Left-sided Colorectal Cancer
Genmab 960
Testing effectiveness (Phase 2)Looking for participantsNCT06542588
What this trial is testing

Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy, HLX07and Serplulimab in LARC

Who this might be right for
Rectal Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 29
Large-scale testing (Phase 3)UnknownNCT04262635
What this trial is testing

Cetuximab Plus Capecitabine as Maintenance Treatment in RAS and BRAF wt Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Sun Yat-sen University 80
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07683403
What this trial is testing

Savolitinib Plus Cetuximab and FOLFOX Chemotherapy for RAS/BRAF Wild-type Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer (CRC)
Fudan University 138
Large-scale testing (Phase 3)Looking for participantsNCT06509126
What this trial is testing

Intermittent or Continuous Panitumumab Plus FOLFIRI for Left Sided RAS/B-RAF Wild-type Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Stage IV
National Cancer Institute, Naples 500
Testing effectiveness (Phase 2)Looking for participantsNCT07044908
What this trial is testing

TQB2922 and TAS-102 Tablets for Injection With or Without Bevacizumab in Chemotherapy-failed RAS/BRAF Wild-type Advanced Colorectal Cancer

Who this might be right for
RAS/BRAF Wild Type Colorectal Cancer
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. 72
Testing effectiveness (Phase 2)Study completedNCT04787341
What this trial is testing

PAnitumumab REchallenge Followed by REgorafenib Versus the Reverse Sequence

Who this might be right for
Colorectal Cancer
Gruppo Oncologico del Nord-Ovest 213
Testing effectiveness (Phase 2)Looking for participantsNCT06776757
What this trial is testing

Sintilimab in Combination with Cetuximab and Chemotherapy As First-line Treatment for RAS/BRAF Wild-type Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center 30
Large-scale testing (Phase 3)Study completedNCT03231722
What this trial is testing

First Line mFOLFOXIRI + PANITUMUMAB vs mFOLFOX + PANITUMUMAB IN RAS AND BRAF WT METASTATIC COLORECTAL CANCER PATIENTS

Who this might be right for
Metastatic Colorectal Cancer
Gruppo Oncologico del Nord-Ovest 435
Large-scale testing (Phase 3)UnknownNCT05074966
What this trial is testing

The Efficacy and Safety of Modified XELOX(mXELOX) Plus Cetuximab vs FOLFOX Plus Cetuximab in RAS and BRAF WT mCRC Pts

Who this might be right for
Colo-rectal Cancer
Chinese Academy of Medical Sciences 314
Post-approval studies (Phase 4)UnknownNCT06550453
What this trial is testing

Safety and Efficacy of Pembrolizumab in Combination with Bevacizumab + CapeOX in the Neoadjuvant Treatment of RAS-mutated, BRAF Wild-type, Microsatellite-stabilized, Locally Advanced Colorectal Cancer

Who this might be right for
Locally Advanced Colorectal Cancer
yangjianjun 20
Testing effectiveness (Phase 2)UnknownNCT03405272
What this trial is testing

Safety and Efficacy of Recombinant Anti-EGFR Monoclonal Antibody in Patients With Wild-type RAS and BRAF mCRC

Who this might be right for
Metastatic Colorectal Cancer
Sinocelltech Ltd. 110
Large-scale testing (Phase 3)Not Yet RecruitingNCT06959693
What this trial is testing

A Clinical Study to Evaluate the Efficacy and Safety of Envafolimab Combined With Cetuxima-βand mFOLFOX6 in Patients With MSS, RAS/BRAF Wild-Type Metastatic Colorectal Cancer (mCRC)

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Sun Yat-sen University 590
Testing effectiveness (Phase 2)UnknownNCT05468177
What this trial is testing

Cetuximab in Combination With Anti-PD-1 and mFOLFOX Treat For RAS/BRAF wt Right-Sided Colon Cancer

Who this might be right for
Colonic Neoplasms
Tongji Hospital 66
Testing effectiveness (Phase 2)Study completedNCT03142516
What this trial is testing

FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status

Who this might be right for
Colorectal NeoplasmsColorectal CarcinomaColorectal Cancer Metastatic+1 more
Grupo Espanol Multidisciplinario del Cancer Digestivo 20
Large-scale testing (Phase 3)Looking for participantsNCT06280495
What this trial is testing

Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients

Who this might be right for
Colorectal CancerLiver Metastases
Sun Yat-sen University 156
Testing effectiveness (Phase 2)UnknownNCT06231017
What this trial is testing

Adebrelimab Plus Cetuximab and Chemotherapy for Patients With RAS/BRAF Wild-Type Unresectable Liver Metastases Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
The First Affiliated Hospital of Zhengzhou University 36
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