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Results for “RASopathies”

12 trials

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Showing 12 of 12 results

Testing effectiveness (Phase 2)Ended earlyNCT03504501
What this trial is testing

Synaptic Plasticity and Cognitive Function in RASopathies

Who this might be right for
Impaired Synaptic PlasticityImpaired Cognition
Technical University of Munich 16
Not applicableLooking for participantsNCT07464821
What this trial is testing

National Multicentre Study on Lipid Profile in Noonan Syndrome and Related Disorders: Trends by Age, Gender and Genotype

Who this might be right for
RASopathiesNoonan Syndrome
IRCCS Azienda Ospedaliero-Universitaria di Bologna 200
Not applicableLooking for participantsNCT05761314
What this trial is testing

Solid Tumors in RASopathies

Who this might be right for
RASopathyCostello SyndromeCardio-Facio-Cutaneous Syndrome+1 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 100
Not applicableUnknownNCT06355622
What this trial is testing

Prevalence and Characterization of Pain in RASopathies

Who this might be right for
RASopathyCostello SyndromeCardio-Facio-Cutaneous Syndrome+1 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 150
Not applicableAvailableNCT05028166
What this trial is testing

Individual Patient Compassionate Use of Mirdametinib

Who this might be right for
Neurofibromatosis Type 1-Associated Plexiform NeurofibromasHistiocytic NeoplasmOther MAP-K Pathway Driven Diseases
SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany
Not applicableNot Yet RecruitingNCT07005297
What this trial is testing

Clinical Genetics Branch Eligibility Screening Survey

Who this might be right for
MelanomaLi-Fraumeni SyndromePulmonary Blastoma+7 more
National Cancer Institute (NCI) 1,000
Not applicableLooking for participantsNCT06489067
What this trial is testing

Study of the Thyroid Function and Echostructural Morphology in Patients Affected With Rasopathies (ECORAS2023)

Who this might be right for
RASopathy
University of Bari Aldo Moro 115
Not applicableUnknownNCT06331117
What this trial is testing

Effect of RAS/MAPK Pathway Hyperactivation on Growth' and Bone' Profile of the RASopathies

Who this might be right for
RASopathyCostello SyndromeNoonan Syndrome+1 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 120
Not applicableLooking for participantsNCT04888936
What this trial is testing

Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies

Who this might be right for
Costello SyndromeNoonan SyndromeCardiofaciocutaneous Syndrome+3 more
National Cancer Institute (NCI) 500
Not applicableLooking for participantsNCT04395495
What this trial is testing

RASopathy Biorepository

Who this might be right for
RAS MutationNeurofibromatosis 1Noonan Syndrome+11 more
Children's Hospital Medical Center, Cincinnati 1,000
Testing effectiveness (Phase 2)Looking for participantsNCT06555237
What this trial is testing

MEK Inhibitors for the Treatment of Hypertrophic Cardiomyopathy in Patients With RASopathies

Who this might be right for
CardiomegalyNoonan Syndrome
Medical University of Warsaw 40
Not applicableLooking for participantsNCT06776380
What this trial is testing

Pubertal Development in Patients with RASopathies

Who this might be right for
RASopathy
IRCCS Azienda Ospedaliero-Universitaria di Bologna 40