Testing effectiveness (Phase 2)Looking for participantsNCT05443126What this trial is testingEP0031 in Patients With Advanced RET-altered MalignanciesWho this might be right forAdvanced Solid TumorNSCLC Ellipses Pharma 265
Early research (Phase 1)Active Not RecruitingNCT05241834What this trial is testingLOXO-260 in Cancer Patients With a Change in a Particular Gene (RET) That Has Not Responded to TreatmentWho this might be right forCarcinoma, Non-Small-Cell LungThyroid Neoplasms Eli Lilly and Company 70
Early research (Phase 1)Study completedNCT03780517What this trial is testingSafety, Efficacy, and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered TumorsWho this might be right forAdvanced Nonhaematologic Malignancies Boston Pharmaceuticals 117
Testing effectiveness (Phase 2)Looking for participantsNCT04683250What this trial is testingStudy of RET Inhibitor TAS0953/HM06 in Patients with Advanced Solid Tumors with RET Gene AbnormalitiesWho this might be right forRET-altered Non Small Cell Lung CancerRET-altered Solid Tumors Taiho Pharmaceutical Co., Ltd. 244
Testing effectiveness (Phase 2)UnknownNCT05675605What this trial is testingTY-1091 in Patients With Advanced Solid TumorsWho this might be right forRET-altered Non Small Cell Lung CancerMedullary Thyroid CancerRET-altered Papillary Thyroid Cancer+1 more TYK Medicines, Inc 248
Testing effectiveness (Phase 2)UnknownNCT05278364What this trial is testingPhase I/II Study of SY-5007, a RET Inhibitor, in Patients With RET-altered Advanced Solid TumorWho this might be right forNon-Small Cell Lung CancerMedullary Thyroid CancerSolid Tumor Shouyao Holdings (Beijing) Co. LTD 184
Testing effectiveness (Phase 2)Study completedNCT03037385What this trial is testingPhase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid TumorsWho this might be right forRET-altered Non Small Cell Lung CancerMedullary Thyroid CancerRET-altered Papillary Thyroid Cancer+37 more Hoffmann-La Roche 590
Early research (Phase 1)Active Not RecruitingNCT05653869What this trial is testingAPS03118 in Advanced Solid Tumors Harboring RET Mutations or FusionsWho this might be right forRET-altered Solid Tumors Applied Pharmaceutical Science, Inc. 108
Testing effectiveness (Phase 2)Active Not RecruitingNCT03899792What this trial is testingOral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) TumorsWho this might be right forMedullary Thyroid CancerInfantile MyofibromatosisInfantile Fibrosarcoma+2 more Eli Lilly and Company 36