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Results for “Ras-mutated Metastatic Colorectal Cancer”

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Showing 20 of 0 results

Large-scale testing (Phase 3)WithdrawnNCT01646554
What this trial is testing

Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases

Who this might be right for
Colorectal Cancer MetastaticLiver MetastasesKRAS Mutated Colorectal Cancer
European Organisation for Research and Treatment of Cancer - EORTC
Testing effectiveness (Phase 2)UnknownNCT03457896
What this trial is testing

Study of Neratinib +Trastuzumab or Neratinib + Cetuximab in Patients With KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer by HER2 Status

Who this might be right for
Metastatic Colorectal Cancer
NSABP Foundation Inc 35
Testing effectiveness (Phase 2)Ended earlyNCT02175654
What this trial is testing

Regorafenib as Single Agent in Patients With Metastatic Colorectal Cancer (mCRC) With Any RAS or BRAF Mutation Previously Treated With FOLFOXIRI Plus Bevacizumab

Who this might be right for
Colorectal NeoplasmsMetastatic Disease
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) 15
Testing effectiveness (Phase 2)UnknownNCT04310176
What this trial is testing

Valproic Acid in Combination With Bevacizumab and Oxaliplatin/Fluoropyrimidine Regimens in Patients With Ras-mutated Metastatic Colorectal Cancer

Who this might be right for
Ras-mutated Metastatic Colorectal Cancer
National Cancer Institute, Naples 200
Testing effectiveness (Phase 2)Looking for participantsNCT05786924
What this trial is testing

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Who this might be right for
Non-small Cell Lung CancerHistiocytic NeoplasmHistiocytosis+29 more
Institut de Recherches Internationales Servier 554
Testing effectiveness (Phase 2)UnknownNCT04194359
What this trial is testing

Sintilimab (IBI308) Combined With Bevacizumab + XELOX Regimen in Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal CancerRAS MutationMicrosatellite Stable
Second Affiliated Hospital, Zhejiang University, School of Medicine 25
Testing effectiveness (Phase 2)Looking for participantsNCT05727163
What this trial is testing

FOLFOX Via HAI Plus Intravenous Irinotecan With or Without Bevacizumab Versus Systemic FOLFOXIRI With or Without Bevacizumab in Initially Unresectable RAS-mutated CRLM Patients

Who this might be right for
Colorectal Cancer Metastatic
Sun Yat-sen University 194
Large-scale testing (Phase 3)Active Not RecruitingNCT05171660
What this trial is testing

Combination With Sintilimab and XELOX+Bevacizumab as 1st Line Therapy in RAS-mutant Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Stage IV
Second Affiliated Hospital, Zhejiang University, School of Medicine 446
Not applicableUnknownNCT04852250
What this trial is testing

Centralized Tumour Board and Secondary Intervention Rate in mCRC

Who this might be right for
Metastatic Colorectal CancerRAS MutationMultidisciplinary Communication+1 more
Ludwig-Maximilians - University of Munich 130
Testing effectiveness (Phase 2)Study completedNCT02350530
What this trial is testing

FOLFOXIRI With or Without Bevacizumab as First-line Treatment for Unresectable Liver-only Metastatic Colorectal Cancer Patients With RAS Mutation-type

Who this might be right for
Metastatic Colorectal Cancer
Sun Yat-sen University 138
Testing effectiveness (Phase 2)Looking for participantsNCT06445062
What this trial is testing

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Who this might be right for
Colorectal CancerCRCPancreatic Ductal Adenocarcinoma+3 more
Revolution Medicines, Inc. 1,130
Testing effectiveness (Phase 2)Looking for participantsNCT07020221
What this trial is testing

VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

Who this might be right for
Pancreatic Ductal AdenocarcinomaNon Small Cell Lung CancerColorectal Cancer+2 more
Verastem, Inc. 295
Testing effectiveness (Phase 2)Looking for participantsNCT07446322
What this trial is testing

FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer

Who this might be right for
Ras-mutated Metastatic Colorectal CancermCRCMSS Metastatic Colorectal Cancer
Oncolytics Biotech 60
Testing effectiveness (Phase 2)Looking for participantsNCT06128551
What this trial is testing

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)Colorectal CancerPancreatic Ductal Adenocarcinoma
Revolution Medicines, Inc. 534
Testing effectiveness (Phase 2)Looking for participantsNCT07397338
What this trial is testing

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

Who this might be right for
Advanced Solid TumorsMetastatic Solid TumorsNon-small Cell Lung Cancer (NSCLC)+3 more
Revolution Medicines, Inc. 370
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07622550
What this trial is testing

A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Serplulimab and Chemotherapy as First-line Treatment for Patients With RAS/BRAF-mutated Advanced Colorectal Cance

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Jiangsu Cancer Institute & Hospital 80
Testing effectiveness (Phase 2)Study completedNCT03271047
What this trial is testing

Study of Binimetinib + Nivolumab Plus or Minus Ipilimumab in Patients With Previously Treated Microsatellite-stable (MSS) Metastatic Colorectal Cancer With RAS Mutation

Who this might be right for
MSSRAS-mutant Colorectal Cancer
Pfizer 75
Testing effectiveness (Phase 2)Study completedNCT00019331
What this trial is testing

Vaccine Therapy Plus Biological Therapy in Treating Adults With Metastatic Solid Tumors

Who this might be right for
Colorectal CancerEndometrial CancerHead and Neck Cancer+6 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT01116271
What this trial is testing

Study of Selumetinib (AZD6244)(ARRY-142886) in Combination With Irinotecan in Previously Treated Patients With Colorec

Who this might be right for
Colorectal Cancer
AstraZeneca 32
Not applicableUnknownNCT03401957
What this trial is testing

The Emergence of RAS Mutations in Metastatic Colorectal Cancer Patients Receiving Cetuximab Treatment

Who this might be right for
Colorectal CancerDrug ResistanceMass Spectrometry+1 more
National Health Research Institutes, Taiwan 120
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