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Results for “Recurrent DIPG”

24 trials

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Showing 20 of 24 results

Early research (Phase 1)Active Not RecruitingNCT03389802
What this trial is testing

Phase I Study of APX005M in Pediatric Central Nervous System Tumors

Who this might be right for
Glioblastoma MultiformeHigh-grade Astrocytoma Not Otherwise Specified (NOS)CNS Primary Tumor, Not Otherwise Specified (NOS)+3 more
Pediatric Brain Tumor Consortium 32
Not applicableUnknownNCT04670016
What this trial is testing

HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers

Who this might be right for
DIPGBrain Tumor, Pediatric, RecurrentBrain Tumor, DIPG+3 more
University of Calgary 57
Testing effectiveness (Phase 2)Study completedNCT01469247
What this trial is testing

Diffuse Intrinsic Pontine Glioma (DIPG) Reirradiation (ReRT)

Who this might be right for
Brain Cancer
M.D. Anderson Cancer Center 12
Early research (Phase 1)Study completedNCT02644460
What this trial is testing

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaBrain Tumor, RecurrentSolid Tumor, Recurrent+5 more
Emory University 53
Early research (Phase 1)Study completedNCT04295759
What this trial is testing

INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas

Who this might be right for
Glioblastoma MultiformeAnaplastic AstrocytomaAnaplastic Oligodendroglioma+3 more
Pediatric Brain Tumor Consortium 13
Testing effectiveness (Phase 2)Looking for participantsNCT06838676
What this trial is testing

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

Who this might be right for
Diffuse Intrinsic Pontine Gliomas (DIPG)Progressive DIPGRefractory DIPG+2 more
Nationwide Children's Hospital 60
Early research (Phase 1)Active Not RecruitingNCT02359565
What this trial is testing

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Who this might be right for
Constitutional Mismatch Repair Deficiency SyndromeLynch SyndromeMalignant Glioma+8 more
National Cancer Institute (NCI) 71
Testing effectiveness (Phase 2)Active Not RecruitingNCT04758533
What this trial is testing

Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy

Who this might be right for
Diffuse Intrinsic Pontine GliomaMedulloblastoma, Childhood, Recurrent
Hospital Infantil Universitario Niño Jesús, Madrid, Spain 13
Very early researchActive Not RecruitingNCT03893487
What this trial is testing

Fimepinostat in Treating Brain Tumors in Children and Young Adults

Who this might be right for
Diffuse Intrinsic Pontine GliomaRecurrent Anaplastic AstrocytomaRecurrent Glioblastoma+2 more
Sabine Mueller, MD, PhD 30
Not applicableStudy completedNCT03126266
What this trial is testing

Re-Irradiation of Progressive or Recurrent DIPG

Who this might be right for
Recurrent or Progressive Diffuse Intrinsic Pontine Glioma
University of Calgary 27
Not applicableStudy completedNCT03841435
What this trial is testing

Hypofractionated Radiotherapy for Recurrent DIPG

Who this might be right for
Recurrent Diffuse Intrinsic Pontine Glioma
University of Cincinnati 5
Early research (Phase 1)Not Yet RecruitingNCT07331064
What this trial is testing

Gallium Maltolate for the Treatment of Pediatric Patients With Relapsed or Refractory Pediatric High-Grade Glioma and Atypical Teratoid Rhabdoid Tumor

Who this might be right for
High Grade GliomasAtypical Teratoid Rhabdoid Tumors (ATRT)Diffuse Midline Glioma+2 more
Sarah Rumler 15
Early research (Phase 1)Looking for participantsNCT04185038
What this trial is testing

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Who this might be right for
Central Nervous System TumorDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma+8 more
Seattle Children's Hospital 90
Testing effectiveness (Phase 2)Study completedNCT03257631
What this trial is testing

Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

Who this might be right for
Central Nervous System NeoplasmsMedulloblastoma
Celgene 53
Early research (Phase 1)Looking for participantsNCT04837547
What this trial is testing

PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy

Who this might be right for
NeuroblastomaDiffuse Intrinsic Pontine Glioma
University of Florida 24
Early research (Phase 1)Ended earlyNCT04341311
What this trial is testing

Phase I Study of Marizomib + Panobinostat for Children With DIPG

Who this might be right for
Diffuse Intrinsic Pontine GliomaPediatric Brainstem GliomaPediatric Brainstem Gliosarcoma, Recurrent+3 more
Dana-Farber Cancer Institute 4
Testing effectiveness (Phase 2)Looking for participantsNCT05096481
What this trial is testing

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaRecurrent Medulloblastoma
Nationwide Children's Hospital 120
Not applicableActive Not RecruitingNCT03033992
What this trial is testing

Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG

Who this might be right for
Malignant GliomaEpendymomaDiffuse Intrinsic Pontine Glioma
Pediatric Brain Tumor Consortium 80
Early research (Phase 1)Active Not RecruitingNCT05768880
What this trial is testing

Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline GliomaRecurrent CNS Tumor, Adult+2 more
Seattle Children's Hospital 72
Early research (Phase 1)Study completedNCT02644291
What this trial is testing

Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors

Who this might be right for
MedulloblastomaAstrocytoma, Grade IIIGlioblastoma+5 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 16
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