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Results for “Recurrent DIPG”

26 trials

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Showing 20 of 26 results

Early research (Phase 1)Study completedNCT04295759
What this trial is testing

INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas

Who this might be right for
Glioblastoma MultiformeAnaplastic AstrocytomaAnaplastic Oligodendroglioma+3 more
Pediatric Brain Tumor Consortium 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT04758533
What this trial is testing

Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy

Who this might be right for
Diffuse Intrinsic Pontine GliomaMedulloblastoma, Childhood, Recurrent
Hospital Infantil Universitario Niño Jesús, Madrid, Spain 13
Testing effectiveness (Phase 2)Study completedNCT03257631
What this trial is testing

Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

Who this might be right for
Central Nervous System NeoplasmsMedulloblastoma
Celgene 53
Early research (Phase 1)Looking for participantsNCT07664176
What this trial is testing

NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors

Who this might be right for
Diffuse Midline Glioma or Diffuse Intrinsic Pontine GliomaHigh Grade GliomasMedulloblastoma Recurrent+3 more
Children's National Research Institute 30
Early research (Phase 1)Not Yet RecruitingNCT07331064
What this trial is testing

Gallium Maltolate for the Treatment of Pediatric Patients With Relapsed or Refractory Pediatric High-Grade Glioma and Atypical Teratoid Rhabdoid Tumor

Who this might be right for
High Grade GliomasAtypical Teratoid Rhabdoid Tumors (ATRT)Diffuse Midline Glioma+2 more
Sarah Rumler 15
Early research (Phase 1)Looking for participantsNCT04185038
What this trial is testing

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Who this might be right for
Central Nervous System TumorDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma+8 more
Seattle Children's Hospital 90
Early research (Phase 1)Active Not RecruitingNCT05768880
What this trial is testing

Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline GliomaRecurrent CNS Tumor, Adult+2 more
Seattle Children's Hospital 72
Early research (Phase 1)Ended earlyNCT04341311
What this trial is testing

Phase I Study of Marizomib + Panobinostat for Children With DIPG

Who this might be right for
Diffuse Intrinsic Pontine GliomaPediatric Brainstem GliomaPediatric Brainstem Gliosarcoma, Recurrent+3 more
Dana-Farber Cancer Institute 4
Early research (Phase 1)Study completedNCT02644460
What this trial is testing

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaBrain Tumor, RecurrentSolid Tumor, Recurrent+5 more
Emory University 53
Early research (Phase 1)Study completedNCT02644291
What this trial is testing

Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors

Who this might be right for
MedulloblastomaAstrocytoma, Grade IIIGlioblastoma+5 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 16
Testing effectiveness (Phase 2)Temporarily pausedNCT06639607
What this trial is testing

PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma

Who this might be right for
Diffuse Midline GliomaDiffuse Midline High-grade GliomaMedulloblastoma+1 more
Washington University School of Medicine 68
Early research (Phase 1)Ended earlyNCT03967093
What this trial is testing

BXQ-350 in Children and Young Adults With Relapsed Solid Tumors

Who this might be right for
Neoplasms
Bexion Pharmaceuticals, Inc. 9
Testing effectiveness (Phase 2)Looking for participantsNCT05096481
What this trial is testing

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaRecurrent Medulloblastoma
Nationwide Children's Hospital 120
Not applicableStudy completedNCT03126266
What this trial is testing

Re-Irradiation of Progressive or Recurrent DIPG

Who this might be right for
Recurrent or Progressive Diffuse Intrinsic Pontine Glioma
University of Calgary 27
Testing effectiveness (Phase 2)Looking for participantsNCT06838676
What this trial is testing

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

Who this might be right for
Diffuse Intrinsic Pontine Gliomas (DIPG)Progressive DIPGRefractory DIPG+2 more
Nationwide Children's Hospital 60
Early research (Phase 1)Looking for participantsNCT04837547
What this trial is testing

PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy

Who this might be right for
NeuroblastomaDiffuse Intrinsic Pontine Glioma
University of Florida 24
Testing effectiveness (Phase 2)Looking for participantsNCT06607692
What this trial is testing

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

Who this might be right for
Solid Tumor CancerMedulloblastomaHigh Risk Neuroblastoma+19 more
Fundación de investigación HM 25
Not applicableActive Not RecruitingNCT03033992
What this trial is testing

Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG

Who this might be right for
Malignant GliomaEpendymomaDiffuse Intrinsic Pontine Glioma
Children's Oncology Group 80
Early research (Phase 1)Active Not RecruitingNCT02359565
What this trial is testing

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Who this might be right for
Constitutional Mismatch Repair Deficiency SyndromeLynch SyndromeMalignant Glioma+8 more
National Cancer Institute (NCI) 71
Not applicableStudy completedNCT03841435
What this trial is testing

Hypofractionated Radiotherapy for Recurrent DIPG

Who this might be right for
Recurrent Diffuse Intrinsic Pontine Glioma
University of Cincinnati 5
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