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Results for “Recurrent High Risk Myelodysplastic Syndrome”

141 trials

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Showing 20 of 141 results

Early research (Phase 1)Study completedNCT00569283
What this trial is testing

Donor Natural Killer Cell Infusion in Preventing Relapse or Graft Failure in Patients Who Have Undergone Donor Bone Marrow Transplant

Who this might be right for
Cancer
Asan Medical Center 18
Early research (Phase 1)Ended earlyNCT02319369
What this trial is testing

Safety, Tolerability and Pharmacokinetics of Milademetan Alone and With 5-Azacitidine (AZA) in Acute Myelogenous Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myelogenous LeukemiaMyelodysplastic Syndrome
Daiichi Sankyo 74
Testing effectiveness (Phase 2)Study completedNCT01869114
What this trial is testing

Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+7 more
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 57
Testing effectiveness (Phase 2)Study completedNCT00083187
What this trial is testing

VNP40101M in Treating Patients With Acute Myelogenous Leukemia or High-Risk Myelodysplasia

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Neoplasms
Vion Pharmaceuticals 230
Testing effectiveness (Phase 2)Study completedNCT00553202
What this trial is testing

Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia

Who this might be right for
Leukemia
Children's Oncology Group 158
Early research (Phase 1)UnknownNCT00769613
What this trial is testing

Emergency Use of Donor Lymphocytes in Treating Patients Who Have Undergone Donor Stem Cell Transplant and Have Cytomegalovirus Infections

Who this might be right for
Cancer
Milton S. Hershey Medical Center 20
Testing effectiveness (Phase 2)Study completedNCT01839916
What this trial is testing

Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)+61 more
University of Chicago 77
Testing effectiveness (Phase 2)Looking for participantsNCT03214562
What this trial is testing

Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
High Risk Myelodysplastic SyndromeRecurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia
M.D. Anderson Cancer Center 116
Testing effectiveness (Phase 2)Study completedNCT01707004
What this trial is testing

Decitabine and Total-Body Irradiation Followed By Donor Bone Marrow Transplant and Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Myeloid Leukemia in RemissionAdult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities+9 more
University of Wisconsin, Madison 20
Testing effectiveness (Phase 2)Study completedNCT00475150
What this trial is testing

Cediranib Maleate in Treating Patients With Relapsed, Refractory, or Untreated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)+8 more
National Cancer Institute (NCI) 39
Early research (Phase 1)Study completedNCT01300572
What this trial is testing

Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS

Who this might be right for
Chronic Myelomonocytic LeukemiaPreviously Treated Myelodysplastic SyndromeRecurrent Adult Acute Lymphoblastic Leukemia+3 more
Fred Hutchinson Cancer Center 16
Testing effectiveness (Phase 2)Ended earlyNCT00818961
What this trial is testing

Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Cancer

Who this might be right for
LeukemiaLymphomaMyelodysplastic Syndromes+1 more
Northside Hospital, Inc. 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT02935361
What this trial is testing

Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes
University of Southern California 33
Testing effectiveness (Phase 2)Study completedNCT00839982
What this trial is testing

Clofarabine and Cytarabine in Treating Older Patients With AML or High-Risk MDS

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+5 more
Fred Hutchinson Cancer Center 35
Testing effectiveness (Phase 2)Ended earlyNCT00052598
What this trial is testing

Therapeutic Allogeneic Lymphocytes and Aldesleukin in Treating Patients With High-Risk or Recurrent Myeloid Leukemia After Undergoing Donor Stem Cell Transplant

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities+12 more
Fred Hutchinson Cancer Center 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT02861417
What this trial is testing

Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmHigh Risk Acute Myeloid LeukemiaHigh Risk Myelodysplastic Syndrome+11 more
M.D. Anderson Cancer Center 204
Testing effectiveness (Phase 2)Ended earlyNCT03067571
What this trial is testing

Daratumumab in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
High Risk Myelodysplastic SyndromeRecurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia
M.D. Anderson Cancer Center 7
Not applicableActive Not RecruitingNCT02670525
What this trial is testing

Matched Targeted Therapy For High-Risk Leukemias and Myelodysplastic Syndrome

Who this might be right for
Recurrent, Refractory, or High Risk LeukemiasMatched Targeted Therapy
Dana-Farber Cancer Institute 338
Early research (Phase 1)Study completedNCT00588991
What this trial is testing

Veliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leukemia, High-Risk Myelodysplasia, or Aggressive Myeloproliferative Disorders

Who this might be right for
Adult Acute Megakaryoblastic LeukemiaAdult Acute Monoblastic LeukemiaAdult Acute Monocytic Leukemia+20 more
National Cancer Institute (NCI) 12
Early research (Phase 1)Ended earlyNCT04477291
What this trial is testing

CG-806 in Patients With Relapsed or Refractory AML or Higher-Risk MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Aptose Biosciences Inc. 45
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