Testing effectiveness (Phase 2)Study completedNCT01497860What this trial is testingVinorelbine for Children With Progressive or Recurrent Low-grade GliomasWho this might be right forLow-grade Glioma Eugene Hwang 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT01089101What this trial is testingSelumetinib in Treating Young Patients With Recurrent or Refractory Low Grade GliomaWho this might be right forLow Grade GliomaRecurrent Childhood Pilocytic AstrocytomaRecurrent Neurofibromatosis Type 1+3 more National Cancer Institute (NCI) 217
Testing effectiveness (Phase 2)Study completedNCT03213665What this trial is testingTazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)Who this might be right forAdvanced Malignant Solid NeoplasmAnn Arbor Stage III Hodgkin LymphomaAnn Arbor Stage III Non-Hodgkin Lymphoma+38 more National Cancer Institute (NCI) 20
Early research (Phase 1)Study completedNCT00052780What this trial is testingTemozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain TumorsWho this might be right forChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+22 more National Cancer Institute (NCI) 72
Testing effectiveness (Phase 2)Looking for participantsNCT04923126What this trial is testingSJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade GliomaWho this might be right forLow-Grade GliomaRecurrent Low-Grade GliomaProgressive Low-Grade Glioma St. Jude Children's Research Hospital 132
Testing effectiveness (Phase 2)Study completedNCT00003466What this trial is testingTemozolomide in Treating Patients With Progressive Low-Grade GliomaWho this might be right forBrain and Central Nervous System Tumors Duke University 100
Large-scale testing (Phase 3)Active Not RecruitingNCT04576117What this trial is testingCompare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade GliomaWho this might be right forRecurrent Low Grade AstrocytomaRecurrent WHO Grade 2 GliomaRefractory Low Grade Astrocytoma+2 more National Cancer Institute (NCI) 300
Early research (Phase 1)Study completedNCT00138216What this trial is testingTemozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid TumorsWho this might be right forBrain and Central Nervous System TumorsUnspecified Childhood Solid Tumor, Protocol Specific Children's Oncology Group 42
Early research (Phase 1)Study completedNCT00063973What this trial is testingCilengitide in Treating Children With Refractory Primary Brain TumorsWho this might be right forChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+23 more National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Ended earlyNCT01338857What this trial is testingSorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade AstrocytomasWho this might be right forneurofibromatosis1 (NF1)Recurrent or Progressive Optic Pathway Gliomas (OPG)Recurrent or Progressive Low-grade Glioma NYU Langone Health 12
Testing effectiveness (Phase 2)Study completedNCT00381797What this trial is testingBevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade GliomaWho this might be right forChildhood Cerebral Anaplastic AstrocytomaChildhood OligodendrogliomaChildhood Spinal Cord Neoplasm+3 more National Cancer Institute (NCI) 97
Testing effectiveness (Phase 2)Looking for participantsNCT04775485What this trial is testingEvaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid TumorsWho this might be right forLow-grade GliomaAdvanced Solid Tumor Day One Biopharmaceuticals, Inc. 141
Testing effectiveness (Phase 2)Study completedNCT00615927What this trial is testingPhase II Imatinib + Hydroxyurea in Treatment of Patients With Recurrent/Progressive Grade II Low-Grade Glioma (LGG)Who this might be right forGlioblastomaGliosarcoma Duke University 64
Not applicableStudy completedNCT00276640What this trial is testingRadiation Therapy or Combination Chemotherapy in Treating Patients With Clinically or Radiologically Progressive Low-Grade GliomasWho this might be right forPrimary Central Nervous System Neoplasms Societe Internationale d'Oncologie Pediatrique 3,417
Not applicableUnknownNCT00891722What this trial is testingTumor Tissue, Blood Samples, and Family History in Predicting Tumor Development and Response to Treatment in Young Patients With Low-Grade GliomaWho this might be right forBrain and Central Nervous System Tumors Children's Cancer and Leukaemia Group 900
Testing effectiveness (Phase 2)Study completedNCT01024907What this trial is testingProton Beam Radiation Therapy in Treating Patients With Low Grade GliomasWho this might be right forAdult Brain TumorAdult Brain Stem GliomaAdult Diffuse Astrocytoma+9 more Abramson Cancer Center at Penn Medicine 23
Testing effectiveness (Phase 2)Study completedNCT00238264What this trial is testingRadiation Therapy in Treating Young Patients With GliomasWho this might be right forBrain TumorCentral Nervous System Tumor Children's Oncology Group 92
Testing effectiveness (Phase 2)Ended earlyNCT01966809What this trial is testingPhotodynamic Therapy (PDT) For Recurrent High Grade GliomasWho this might be right forBrain Tumor, Recurrent Harry T Whelan, MD 1
Testing effectiveness (Phase 2)Study completedNCT01734512What this trial is testingPNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in ChildrenWho this might be right forPediatric Recurrent Progressive Low-grade GliomasPediatric Progressive Low-grade Gliomas University of California, San Francisco 65
Testing effectiveness (Phase 2)Study completedNCT01635283What this trial is testingVaccine for Patients With Newly Diagnosed or Recurrent Low-Grade GliomaWho this might be right forAdult Diffuse AstrocytomaAdult Mixed GliomaAdult Oligodendroglioma+2 more Jonsson Comprehensive Cancer Center 5