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Results for “Reduced Systolic Function”

40 trials

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Showing 20 of 40 results

Not applicableNot Yet RecruitingNCT07275437
What this trial is testing

Effectiveness and Safety of Uptitration of Guideline Directed MEdical Therapy in Heart Failure With Reduced Ejection Fraction With Limited Kidney Function Assessments

Who this might be right for
Heart FailureHeart Failure and Reduced Ejection FractionHeart Failure and Mildly Reduced Ejection Fraction
University Medical Center Groningen 344
Very early researchLooking for participantsNCT06108076
What this trial is testing

Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes

Who this might be right for
Type 2 DiabetesHeart Failure, Reduced Ejection Fraction
The University of Texas Health Science Center at San Antonio 10
Testing effectiveness (Phase 2)Study completedNCT00616161
What this trial is testing

A Phase II Trial to Assess Hemodynamic Effects of Istaroxime in Pts With Worsening HF and Reduced LV Systolic Function

Who this might be right for
Heart Failure
sigma-tau i.f.r. S.p.A. 120
Testing effectiveness (Phase 2)WithdrawnNCT01798745
What this trial is testing

Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic Receptor Autoantibodies

Who this might be right for
Heart Failure
Janssen Research & Development, LLC
Testing effectiveness (Phase 2)Study completedNCT01904903
What this trial is testing

Cardiac Safety Study in Patients With HER2 + Breast Cancer

Who this might be right for
HER2 Positive Breast CancerLeft Ventricular Function Systolic Dysfunction
Medstar Health Research Institute 31
Not applicableEnrolling By InvitationNCT07253909
What this trial is testing

Upper Extremity Function in Patients With Reduced Ejection Fraction Heart Failure and Cardiac Implantable Electronic Devices

Who this might be right for
Heart FailureImplantable Cardioverter Defibrillator (ICD)Cardiac Resynchronisation Therapy (CRT)+1 more
Hacettepe University 72
Large-scale testing (Phase 3)Study completedNCT00634400
What this trial is testing

Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Alternative)

Who this might be right for
Congestive Heart Failure
AstraZeneca 6,268
Not applicableLooking for participantsNCT07430553
What this trial is testing

Comparing Three Types of Specialist Pacemakers to Improve Heart Function and Reduce Rhythm Problems in Heart Failure

Who this might be right for
Heart Failure and Reduced Ejection FractionDyssynchrony
Imperial College London 60
Large-scale testing (Phase 3)Study completedNCT00634712
What this trial is testing

Candesartan Cilexetil in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Preserved)

Who this might be right for
Congestive Heart Failure
AstraZeneca 734
Not applicableStudy completedNCT03641599
What this trial is testing

Right Ventricular Function in Heart Failure

Who this might be right for
Assessment of the RV Function in Patients With Heart Faliure
shaimaa Mostafa 150
Early research (Phase 1)WithdrawnNCT00869115
What this trial is testing

Phase I Interaction Study of Istaroxime and Digoxin in Subjects With Stable Heart Failure

Who this might be right for
Heart Failure
Debiopharm International SA
Post-approval studies (Phase 4)Study completedNCT03300427
What this trial is testing

The Effects of Sacubitril/Valsartan on Cardiac Oxygen Consumption and Efficiency of Cardiac Work in Heart Failure Patients

Who this might be right for
Heart Failure
Novartis Pharmaceuticals 55
Not applicableLooking for participantsNCT06324682
What this trial is testing

ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing

Who this might be right for
Arrhythmias, CardiacAtrioventricular BlockReduced Systolic Function+22 more
University Hospital of Ferrara 8,400
Not applicableStudy completedNCT03470155
What this trial is testing

Operative Mitral Valve Reconstruction in Functional mv Insufficiency With Reduced Systolic Ventricle Function

Who this might be right for
Mitral Valve InsufficiencyLeft Ventricular Systolic DysfunctionMitral Valve Prolapse
Institut für Pharmakologie und Präventive Medizin 105
Large-scale testing (Phase 3)Ended earlyNCT00534456
What this trial is testing

An Exploratory Sub-study for the RED-HF™ (Reduction of Events With Darbepoetin Alfa in Heart Failure) Trial

Who this might be right for
AnemiaCardiovascular DiseaseCongestive Heart Failure+2 more
Amgen 12
Large-scale testing (Phase 3)Study completedNCT00634309
What this trial is testing

Candesartan Cilexetil in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Added)

Who this might be right for
Congestive Heart Failure
AstraZeneca 597
Post-approval studies (Phase 4)Study completedNCT02653482
What this trial is testing

Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure

Who this might be right for
Chronic Heart Failure With Reduced Systolic Function
Saint Luke's Health System 263
Large-scale testing (Phase 3)Study completedNCT04231331
What this trial is testing

Ertugliflozin for Functional Mitral Regurgitation

Who this might be right for
Mitral Valve InsufficiencyLeft Ventricular Systolic Dysfunction
Asan Medical Center 128
Not applicableStudy completedNCT05651529
What this trial is testing

Acute Oral Ketones or Carbohydrate Supplement Modify Heart Function in Heart Failure?

Who this might be right for
Heart Failure
Université de Sherbrooke 20
Not applicableUnknownNCT06528366
What this trial is testing

Heart Failure With Reduced Ejection Fraction: Adjuvant Therapy With Neurostimulation and Chlorella Pyrenoidosa (HD-tDCS)

Who this might be right for
Heart Failure, Reduced Ejection FractionVitamin B12 Deficiency
Federal University of Paraíba 28
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