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Results for “Refractory High Risk Myelodysplastic Syndrome”

209 trials

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Showing 20 of 209 results

Early research (Phase 1)Study completedNCT01757639
What this trial is testing

Ipilimumab in Treating Patients With Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeChronic Myelomonocytic LeukemiaMyelodysplastic Syndrome+3 more
National Cancer Institute (NCI) 42
Testing effectiveness (Phase 2)Looking for participantsNCT06802315
What this trial is testing

Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myeloid Leukemia, Relapsed, AdultAcute Myeloid Leukemia RefractoryChronic Myeloid Leukemia - Accelerated Phase+1 more
University of Illinois at Chicago
Early research (Phase 1)Looking for participantsNCT06594445
What this trial is testing

HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML

Who this might be right for
Myeloid MalignancyAcute Myeloid LeukemiaMyelodysplastic Syndromes
Masonic Cancer Center, University of Minnesota 45
Early research (Phase 1)Study completedNCT00077558
What this trial is testing

3-AP Followed By Fludarabine In Treating Patients With Relapsed or Refractory Acute or Chronic Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Diseases
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Testing effectiveness (Phase 2)Looking for participantsNCT04140487
What this trial is testing

Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent/Refractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Chronic Myelomonocytic LeukemiaRecurrent Myelodysplastic/Myeloproliferative Neoplasm+3 more
M.D. Anderson Cancer Center
Not applicableUnknownNCT02905552
What this trial is testing

Myelodysplasic Syndromes and Risk Factors for Infection

Who this might be right for
Myelodysplastic Syndrome (MDS)InfectionRisk Factors+1 more
Assistance Publique - Hôpitaux de Paris 320
Testing effectiveness (Phase 2)Looking for participantsNCT05601726
What this trial is testing

First-in-human Study Aiming to Characterize the Safety, Tolerability, Pharmacokinetic and Preliminary Signs of Activity of ABD-3001 in Refractory or Relapsed AML and High Risk MDS Adult Patients

Who this might be right for
Acute Myeloid Leukemia, AdultMyelodysplastic Syndromes
Advanced BioDesign 36
Testing effectiveness (Phase 2)Study completedNCT00064311
What this trial is testing

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

Who this might be right for
Breast CancerChronic Myeloproliferative DisordersGestational Trophoblastic Tumor+9 more
National Institutes of Health Clinical Center (CC)
Testing effectiveness (Phase 2)UnknownNCT00022321
What this trial is testing

Gemtuzumab in Treating Patients With Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndromes
Jonsson Comprehensive Cancer Center
Testing effectiveness (Phase 2)Looking for participantsNCT03661307
What this trial is testing

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+2 more
M.D. Anderson Cancer Center 73
Testing effectiveness (Phase 2)Looking for participantsNCT04493164
What this trial is testing

CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia With Gene MutationsMyelodysplastic SyndromeMyeloproliferative Neoplasm+2 more
M.D. Anderson Cancer Center 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT03674411
What this trial is testing

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphocytic LeukemiaBiphenotypic/Undifferentiated Leukemia+8 more
Masonic Cancer Center, University of Minnesota 22
Testing effectiveness (Phase 2)Study completedNCT02019069
What this trial is testing

CPX-351 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
Adult Acute Erythroid Leukemia (M6)Adult Acute Megakaryoblastic Leukemia (M7)Adult Acute Minimally Differentiated Myeloid Leukemia (M0)+13 more
Rondeep Brar 11
Early research (Phase 1)WithdrawnNCT05456269
What this trial is testing

Bisantrene Combined With Cytarabine or With Decitabine for Adult Subjects With Extramedullary AML and MDS

Who this might be right for
Acute Myeloid LeukemiaRecurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia+2 more
Race Oncology Ltd
Early research (Phase 1)Looking for participantsNCT05829226
What this trial is testing

Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS)

Who this might be right for
AML, Adult RecurrentMDS
PureTech 90
Testing effectiveness (Phase 2)Ended earlyNCT00740181
What this trial is testing

Decitabine, Cytarabine, GCSF for Refractory AML/MDS

Who this might be right for
MyelodysplasiaLeukemia
Brown University 9
Testing effectiveness (Phase 2)Ended earlyNCT02152956
What this trial is testing

Flotetuzumab in Primary Induction Failure (PIF) or Early Relapse (ER) Acute Myeloid Leukemia (AML)

Who this might be right for
AML
MacroGenics 244
Testing effectiveness (Phase 2)WithdrawnNCT00003984
What this trial is testing

Monoclonal Antibody Therapy in Treating Patients With Primary Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndromes
European Organisation for Research and Treatment of Cancer - EORTC
Not applicableStudy completedNCT02007863
What this trial is testing

Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and Myelodysplasia

Who this might be right for
LeukemiaMyelodysplasiaAcute Lymphocytic Leukemia+1 more
University of Miami 2
Early research (Phase 1)Looking for participantsNCT06501196
What this trial is testing

BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

Who this might be right for
LeukemiaLeukemia, MyeloidLeukemia, Myeloid, Acute+3 more
BlossomHill Therapeutics 170
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