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Results for “Refractory Langerhans Cell Histiocytosis”

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Showing 20 of 0 results

Large-scale testing (Phase 3)UnknownNCT06038422
What this trial is testing

GTP Regimen in the Treatment of Refractory/Recurrent HLH

Who this might be right for
RefractoryRecurrenceHemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 15
Early research (Phase 1)UnknownNCT05477446
What this trial is testing

Safety and Efficacy of CD207 Targeted CAR-T Cell Therapy in Patients With R/R Langerhans Cell Histiocytosis

Who this might be right for
Langerhans Cell Histiocytosis
Beijing Friendship Hospital 12
Testing effectiveness (Phase 2)Study completedNCT03233204
What this trial is testing

Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+33 more
National Cancer Institute (NCI) 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213704
What this trial is testing

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor+30 more
National Cancer Institute (NCI) 9
Large-scale testing (Phase 3)UnknownNCT03533790
What this trial is testing

DEP-Ru Regimen as a Salvage Therapy for HLH

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 80
Testing effectiveness (Phase 2)WithdrawnNCT01796405
What this trial is testing

Clofarabine for Langerhans in Pedi

Who this might be right for
Langerhans Cell Histiocytosis
Dana-Farber Cancer Institute
Testing effectiveness (Phase 2)Study completedNCT03526250
What this trial is testing

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Ewing Sarcoma+29 more
National Cancer Institute (NCI) 23
Large-scale testing (Phase 3)UnknownNCT04120090
What this trial is testing

Ruxolitinib as a Salvage Therapy for Hemophagocytic Lymphohistiocytosis

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 80
Testing effectiveness (Phase 2)Active Not RecruitingNCT02574728
What this trial is testing

Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors

Who this might be right for
Cancer
Emory University 46
Testing effectiveness (Phase 2)Active Not RecruitingNCT04551131
What this trial is testing

Use Of A Response-Adapted Ruxolitinib-Containing Regimen For The Treatment Of Hemophagocytic Lymphohistiocytosis

Who this might be right for
Hemophagocytic Lymphohistiocytosis
St. Jude Children's Research Hospital 10
Testing effectiveness (Phase 2)Looking for participantsNCT05997602
What this trial is testing

To Evaluate the Efficacy, Safety, and PK Characteristics of FCN-159 in Pediatric Patients With Refractory/Recurrent LCH

Who this might be right for
Langerhans Cell HistiocytosisLCH
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 56
Testing effectiveness (Phase 2)UnknownNCT03795909
What this trial is testing

Ruxolitinib Combined With Dexamethasone for HLH

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Capital Research Institute of Pediatrics 50
Testing effectiveness (Phase 2)UnknownNCT04405375
What this trial is testing

GPED Regimen for Relapsed/Refractory or Advanced ENKTCL

Who this might be right for
Extranodal NK/T-cell Lymphoma, Nasal Type
Beijing Tongren Hospital 29
Testing effectiveness (Phase 2)UnknownNCT00084695
What this trial is testing

Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases

Who this might be right for
Childhood Langerhans Cell HistiocytosisFanconi AnemiaLeukemia+5 more
Milton S. Hershey Medical Center 25
Testing effectiveness (Phase 2)Active Not RecruitingNCT03210714
What this trial is testing

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Childhood Malignant Germ Cell Tumor+29 more
National Cancer Institute (NCI) 20
Not applicableEnded earlyNCT00008216
What this trial is testing

Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer

Who this might be right for
Adult Langerhans Cell HistiocytosisChildhood Langerhans Cell HistiocytosisLeukemia+4 more
Columbia University 48
Testing effectiveness (Phase 2)Active Not RecruitingNCT04284774
What this trial is testing

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Malignant Solid NeoplasmRecurrent Adrenal Gland PheochromocytomaRecurrent Ectomesenchymoma+38 more
National Cancer Institute (NCI) 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT03698994
What this trial is testing

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Ependymal TumorRecurrent Ewing Sarcoma+33 more
National Cancer Institute (NCI) 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT03155620
What this trial is testing

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+42 more
National Cancer Institute (NCI) 1,377
Early research (Phase 1)Ended earlyNCT00002947
What this trial is testing

Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Langerhans Cell HistiocytosisGastrointestinal Carcinoid Tumor+9 more
Yale University 35
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