Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Refractory Metastatic Colorectal Cancer”

254 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 254 results

Early research (Phase 1)UnknownNCT05213195
What this trial is testing

NKG2D CAR-NK Cell Therapy in Patients With Refractory Metastatic Colorectal Cancer

Who this might be right for
Refractory Metastatic Colorectal Cancer
Zhejiang University 38
Testing effectiveness (Phase 2)Study completedNCT03647839
What this trial is testing

Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Australasian Gastro-Intestinal Trials Group 90
Large-scale testing (Phase 3)Active Not RecruitingNCT06614192
What this trial is testing

A Study Assessing Adverse Events and Disease Activity of Intravenously (IV) Infused Telisotuzumab Adizutecan in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
AbbVie 74
Early research (Phase 1)Ended earlyNCT02908451
What this trial is testing

AbGn-107 in Patients With Gastric, Colorectal, Pancreatic or Biliary Cancer

Who this might be right for
Gastric CancerColorectal CancerPancreatic Cancer+1 more
AbGenomics B.V Taiwan Branch 39
Not applicableWithdrawnNCT06221423
What this trial is testing

Fruquintinib Combined With TAS-102 in Refractory Metastatic Colorectal Cancer

Who this might be right for
Colorectal CancerMetastatic Colorectal CancerRefractory Colorectal Carcinoma
Fudan University
Testing effectiveness (Phase 2)Study completedNCT03475004
What this trial is testing

Study of Pembrolizumab, Binimetinib, and Bevacizumab in Patients With Refractory Colorectal Cancer

Who this might be right for
Colorectal CancerMetastatic Cancer
University of Colorado, Denver 53
Testing effectiveness (Phase 2)Active Not RecruitingNCT05608044
What this trial is testing

Botensilimab and Balstilimab for the Treatment of Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Agenus Inc. 234
Testing effectiveness (Phase 2)Active Not RecruitingNCT04294264
What this trial is testing

TAS-102 and Oxaliplatin for the Treatment of Refractory Stage IV Colon Cancer

Who this might be right for
Metastatic Colorectal CarcinomaRecurrent Colon CarcinomaRefractory Colorectal Carcinoma+3 more
Rutgers, The State University of New Jersey 50
Testing effectiveness (Phase 2)Study completedNCT02873195
What this trial is testing

Capecitabine and Bevacizumab With or Without Atezolizumab in Treating Patients With Refractory Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal CarcinomaRecurrent Colorectal CarcinomaRefractory Colorectal Carcinoma+3 more
Academic and Community Cancer Research United 133
Testing effectiveness (Phase 2)Looking for participantsNCT07012954
What this trial is testing

CtDNA-Guided Cetuximab or Bevacizumab Plus Trifluridine/Tipiracil in RAS/BRAF Wild-Type mCRC

Who this might be right for
Colorectal Cancer Metastatic
Sun Yat-sen University 64
Testing effectiveness (Phase 2)Study completedNCT00107861
What this trial is testing

Interferon-Beta Gene Transfer (Ad.hIFN-β) as Treatment for Refractory Colorectal Carcinoma With Liver Metastases

Who this might be right for
Colorectal CarcinomaMetastases
Biogen 44
Early research (Phase 1)Study completedNCT00667641
What this trial is testing

Paclitaxel and Bortezomib in Treating Patients With Metastatic or Unresectable Malignant Solid Tumors

Who this might be right for
Breast CancerColorectal CancerHead and Neck Cancer+6 more
University of Medicine and Dentistry of New Jersey 16
Testing effectiveness (Phase 2)Study completedNCT02651415
What this trial is testing

Phase II Study of Perindopril and Regorafenib in mCRC

Who this might be right for
Metastatic Colorectal Cancer
British Columbia Cancer Agency 12
Testing effectiveness (Phase 2)Ended earlyNCT03435640
What this trial is testing

REVEAL Study of NKTR-262 in Combination With NKTR-214 and Nivolumab in Patients With Locally Advanced / Metastatic Solid Tumor Malignancies

Who this might be right for
MelanomaMerkel Cell CarcinomaTriple Negative Breast Cancer+4 more
Nektar Therapeutics 64
Testing effectiveness (Phase 2)Ended earlyNCT03610490
What this trial is testing

Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma

Who this might be right for
Malignant Solid NeoplasmMetastatic Colorectal AdenocarcinomaMetastatic Ovarian Carcinoma+9 more
M.D. Anderson Cancer Center 16
Testing effectiveness (Phase 2)Looking for participantsNCT07722754
What this trial is testing

Bevacizumab, Sintilimab, Cetuximab and Irinotecan in Refractory RAS Wild-type Metastatic Colorectal Cancer: BOND-4 Trial

Who this might be right for
Colorectal Neoplasms MalignantNeoplasm, Metastatic
Guangdong Provincial People's Hospital 160
Testing effectiveness (Phase 2)UnknownNCT03567629
What this trial is testing

Evaluate the Efficacy of Irinotecan Versus Oxaliplatin in the First-line Treatment of Refractory Metastatic Colorectal Cancer

Who this might be right for
mCRC
Peking University 130
Testing effectiveness (Phase 2)Looking for participantsNCT06265025
What this trial is testing

GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerMalignant MelanomaColorectal Cancer+3 more
GeneMedicine Co., Ltd. 125
Testing effectiveness (Phase 2)UnknownNCT03608046
What this trial is testing

Avelumab Combined With Cetuximab and Irinotecan for Treatment Refractory Metastatic Colorectal Microsatellite Stable Cancer

Who this might be right for
Colorectal Neoplasms, Malignant
Cliniques universitaires Saint-Luc- Université Catholique de Louvain 59
Large-scale testing (Phase 3)Looking for participantsNCT07525206
What this trial is testing

Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
AbbVie 990
Next Page