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Results for “Refractory Metastatic Colorectal Cancer”

249 trials

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Showing 20 of 249 results

Testing effectiveness (Phase 2)Study completedNCT00827684
What this trial is testing

Temsirolimus and Irinotecan for Treatment Resistant Patients With Metastatic Colorectal Cancer and KRAS Mutations

Who this might be right for
Metastatic Colorectal Cancer
Vejle Hospital 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT04902872
What this trial is testing

Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors

Who this might be right for
Solid Tumor, AdultEpithelial Ovarian CancerSmall Cell Lung Carcinoma+9 more
Cybrexa Therapeutics 130
Large-scale testing (Phase 3)Looking for participantsNCT06614192
What this trial is testing

A Study Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and Tipiracil (LONSURF) Oral Tablets Plus IV Infused Bevacizumab in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
AbbVie 460
Testing effectiveness (Phase 2)Study completedNCT02195011
What this trial is testing

Safety Study of Regorafenib and SIR-Spheres® Microspheres Radioembolization in Patients With Refractory Metastatic Colorectal Cancer With Liver Metastases

Who this might be right for
Colorectal Neoplasms
SCRI Development Innovations, LLC 26
Testing effectiveness (Phase 2)Study completedNCT00016250
What this trial is testing

Ro 31-7453 in Treating Patients With Recurrent or Refractory Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Study completedNCT00593060
What this trial is testing

Temsirolimus (CCI-770, Torisel) Combined With Cetuximab in Cetuximab-Refractory Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal Adenocarcinoma
Jeffrey W. Clark, MD 35
Testing effectiveness (Phase 2)Study completedNCT00068068
What this trial is testing

Photodynamic Therapy With Talaporfin Sodium (LS11) in Treating Patients With Refractory Colorectal Liver Metastases

Who this might be right for
Liver MetastasisColorectal NeoplasmsLiver Neoplasms+1 more
Light Sciences LLC 25
Early research (Phase 1)Looking for participantsNCT04485013
What this trial is testing

TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

Who this might be right for
Cancer
Tizona Therapeutics, Inc 240
Testing effectiveness (Phase 2)Active Not RecruitingNCT04294264
What this trial is testing

TAS-102 and Oxaliplatin for the Treatment of Refractory Stage IV Colon Cancer

Who this might be right for
Metastatic Colorectal CarcinomaRecurrent Colon CarcinomaRefractory Colorectal Carcinoma+3 more
Rutgers, The State University of New Jersey 50
Testing effectiveness (Phase 2)Study completedNCT02368886
What this trial is testing

Lower or Standard Dose Regorafenib in Treating Patients With Refractory Metastatic Colorectal Cancer

Who this might be right for
Colon AdenocarcinomaRectal AdenocarcinomaStage III Colorectal Cancer AJCC v7+6 more
Academic and Community Cancer Research United 123
Testing effectiveness (Phase 2)Study completedNCT03442569
What this trial is testing

PhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC

Who this might be right for
Colon Cancer
UNC Lineberger Comprehensive Cancer Center 56
Early research (Phase 1)Study completedNCT02482441
What this trial is testing

A Phase 1a/b Dose Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of OMP-131R10

Who this might be right for
Advanced Relapsed TumorsRefractory Solid Tumors
OncoMed Pharmaceuticals, Inc. 50
Early research (Phase 1)Study completedNCT02743637
What this trial is testing

A Dose Escalation Study of SDX-7320 in Patients With Advanced Refractory or Late-Stage Solid Tumors

Who this might be right for
Advanced MalignancyAdvanced Solid TumorsNeoplasm+1 more
SynDevRx, Inc. 32
Testing effectiveness (Phase 2)UnknownNCT06039202
What this trial is testing

Phase 2 Study of CA102N Combined With TAS-102 Compared to Bevacizumab Combined With TAS-102 in Subjects With Relapsed and/or Refractory Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Holy Stone Healthcare Co., Ltd 100
Testing effectiveness (Phase 2)Looking for participantsNCT06699836
What this trial is testing

Leronlimab in Combination With TAS-102 + Bevacizumab in Previously Treated Participants With mCRC

Who this might be right for
Metastatic Colorectal Cancer (mCRC)
CytoDyn, Inc. 60
Early research (Phase 1)Ended earlyNCT02110953
What this trial is testing

Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal Cancer That Has Spread to the Liver

Who this might be right for
Liver MetastasesMucinous Adenocarcinoma of the ColonMucinous Adenocarcinoma of the Rectum+8 more
Fox Chase Cancer Center 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT05205330
What this trial is testing

Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers

Who this might be right for
Refractory Metastatic Colorectal CancerSolid TumorMetastatic Microsatellite-stable Colorectal Cancer+3 more
Rottapharm Biotech 107
Testing effectiveness (Phase 2)Study completedNCT00337545
What this trial is testing

Phase II Trial of RAD001 in Refractory Colorectal Cancer

Who this might be right for
Colorectal Cancer
Swedish Medical Center 22
Not applicableStudy completedNCT02135757
What this trial is testing

Study to Evaluate Real-world Pharmacoeconomics and Resistance Mechanisms of Panitumumab in Metastatic Colorectal Cancer Patients

Who this might be right for
Colorectal Cancer Metastatic
PeriPharm 23
Testing effectiveness (Phase 2)Looking for participantsNCT06522919
What this trial is testing

Sequential Immunochemotherapy Treatment with Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticMicrosatellite Stable Colorectal CarcinomaRefractory Mismatch-repair-proficient (pMMR) Metastatic Colorectal Cancer
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
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