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Results for “Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)”

18 trials

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Showing 18 of 18 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05608044
What this trial is testing

Botensilimab and Balstilimab for the Treatment of Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Agenus Inc. 234
Testing effectiveness (Phase 2)Study completedNCT05243862
What this trial is testing

Safety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer.

Who this might be right for
Colorectal Cancer Metastatic
Treos Bio Limited 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT06699836
What this trial is testing

CLOVER - CCR5-targeting Leronlimab With Oral Chemotherapy and VEGF-inhibitor Enriched Regimen

Who this might be right for
Metastatic Colorectal Cancer (mCRC)
CytoDyn, Inc. 66
Testing effectiveness (Phase 2)Ended earlyNCT05572684
What this trial is testing

A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsMicrosatellite Instability LowMicrosatellite Instability High+9 more
NextCure, Inc. 97
Testing effectiveness (Phase 2)Study completedNCT03711058
What this trial is testing

Study of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer

Who this might be right for
Unresectable or Metastatic Microsatellite Stable (MSS) Solid TumorMicrosatellite Stable (MSS) Colon Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 48
Testing effectiveness (Phase 2)Looking for participantsNCT06589440
What this trial is testing

Phase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)

Who this might be right for
Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)
Stingray Therapeutics 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT05205330
What this trial is testing

Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers

Who this might be right for
Refractory Metastatic Colorectal CancerSolid TumorMetastatic Microsatellite-stable Colorectal Cancer+3 more
Rottapharm Biotech 107
Testing effectiveness (Phase 2)Active Not RecruitingNCT04963283
What this trial is testing

Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaColon CancerColon Adenocarcinoma+4 more
University of Colorado, Denver 48
Testing effectiveness (Phase 2)Looking for participantsNCT07281716
What this trial is testing

Combination Immunotherapy for the Treatment of Chemotherapy-refractory Metastatic MSS CRC

Who this might be right for
Metastatic Microsatellite Stable Colorectal Carcinoma
Dan Feng 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT04599140
What this trial is testing

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Colorectal CarcinomaMetastatic Rectal Adenocarcinoma+18 more
M.D. Anderson Cancer Center 51
Testing effectiveness (Phase 2)Study completedNCT03800602
What this trial is testing

Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaMetastatic Microsatellite Stable Colorectal CarcinomaRefractory Colorectal Carcinoma+5 more
Emory University 29
Testing effectiveness (Phase 2)Ended earlyNCT05733611
What this trial is testing

RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC

Who this might be right for
Refractory Metastatic Colorectal CancerpMMRMSS
Replimune, Inc. 5
Early research (Phase 1)Study completedNCT03274804
What this trial is testing

Combined PD-1 and CCR5 Inhibition for the Treatment of Refractory Microsatellite Stable mCRC

Who this might be right for
Metastatic Colorectal CancerMSS
University Hospital Heidelberg 20
Early research (Phase 1)WithdrawnNCT03802747
What this trial is testing

Immunotherapy Combined With Y-90 and SBRT for Colorectal Liver Metastases

Who this might be right for
Colorectal Cancer
University of Colorado, Denver
Testing effectiveness (Phase 2)WithdrawnNCT03182894
What this trial is testing

Epacadostat in Combination With Pembrolizumab and Azacitidine in Subjects With Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
James J Lee
Testing effectiveness (Phase 2)Study completedNCT02860546
What this trial is testing

A Study Evaluating TAS-102 Plus Nivolumab in Patients With MSS CRC

Who this might be right for
Refractory Metastatic Colorectal Cancer
Taiho Oncology, Inc. 18
Testing effectiveness (Phase 2)Ended earlyNCT05167409
What this trial is testing

Study of Evorpacept (ALX148) With Cetuximab and Pembrolizumab for Refractory Microsatellite Stable Metastatic Colorectal Cancer

Who this might be right for
Microsatellite Stable Metastatic Colorectal Cancer
University of Colorado, Denver 19
Testing effectiveness (Phase 2)Looking for participantsNCT06522919
What this trial is testing

Sequential Immunochemotherapy Treatment with Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticMicrosatellite Stable Colorectal CarcinomaRefractory Mismatch-repair-proficient (pMMR) Metastatic Colorectal Cancer
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
36