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Results for “Refractory Myasthenia Gravis”

40 trials

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Showing 20 of 40 results

Large-scale testing (Phase 3)UnknownNCT05332587
What this trial is testing

Efficacy and Safety of Low-dose Rituximab in the Treatment of Refractory Myasthenia Gravis

Who this might be right for
Refractory Myasthenia GravisRituximab
First Affiliated Hospital, Sun Yat-Sen University 50
Very early researchLooking for participantsNCT07337785
What this trial is testing

CD19/BCMA-Targeted UCAR-T for Patients With Neurological Autoimmune Diseases

Who this might be right for
Relapsing or Refractory Multiple Sclerosis (MS)Myasthenia Gravis (MG)Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)+1 more
Daishi Tian 36
Very early researchNot Yet RecruitingNCT06485232
What this trial is testing

Universal CAR-T Cells in Patients with Refractory Autoimmune Diseases of the Nervous System.

Who this might be right for
Neuromyelitis Optica Spectrum DisordersMyasthenia Gravis, GeneralizedMultiple Sclerosis+1 more
Xuanwu Hospital, Beijing 25
Large-scale testing (Phase 3)Study completedNCT02301624
What this trial is testing

Extension Study of ECU-MG-301 to Evaluate Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis

Who this might be right for
Refractory Generalized Myasthenia Gravis
Alexion Pharmaceuticals, Inc. 117
Large-scale testing (Phase 3)Not Yet RecruitingNCT06836973
What this trial is testing

Blinatumomab for Treatment of Refractory Myasthenia Gravis

Who this might be right for
Myasthenia Gravis
Da, Yuwei, M.D. 2
Large-scale testing (Phase 3)Study completedNCT06764160
What this trial is testing

Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Eculizumab in Chinese Adults With gMG

Who this might be right for
Generalized Myasthenia Gravis (gMG)Refractory gMG
Alexion Pharmaceuticals, Inc. 15
Very early researchStudy completedNCT04431895
What this trial is testing

Safety And Efficacy Of Tofacitinib In Patients With Refractory Myasthenia Gravis: A Pilot Study

Who this might be right for
Myasthenia Gravis, Generalized
Huashan Hospital 19
Early research (Phase 1)Looking for participantsNCT06688435
What this trial is testing

Evaluate the Safety and Preliminary Efficacy of SYS6020 CAR T-cells in Patients With Refractory Generalized Myasthenia Gravis

Who this might be right for
Myasthenia Gravis
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 50
Very early researchNot Yet RecruitingNCT07392528
What this trial is testing

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/ BCMA（QT-019C） in Patients With r/ r Neurological Autoimmune Diseases

Who this might be right for
Neuromyelitis Optica Spectrum DisordersMultiple SclerosisMyasthenia Gravis
Tianjin Huanhu Hospital 15
Large-scale testing (Phase 3)Study completedNCT03759366
What this trial is testing

Open-Label Study of Eculizumab in Pediatric Participants With Refractory Generalized Myasthenia Gravis (gMG)

Who this might be right for
Myasthenia GravisMyasthenia Gravis, Juvenile FormMyasthenia Gravis, Generalized
Alexion Pharmaceuticals, Inc. 12
Not applicableNot Yet RecruitingNCT07499323
What this trial is testing

Talquetamab in Patients With Refractory Generalized Myasthenia Gravis

Who this might be right for
Myasthenia Gravis (MG)
First Affiliated Hospital of Chongqing Medical University 2
Early research (Phase 1)Not Yet RecruitingNCT06978738
What this trial is testing

UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusAutoimmune Hemolytic AnemiaMyasthenia Gravis+4 more
Changzhou No.2 People's Hospital 18
Early research (Phase 1)Looking for participantsNCT06869278
What this trial is testing

LCAR-AIO CAR-T Cells for Treating Relapsed/Refractory Neurological Autoimmune Diseases

Who this might be right for
Multiple Sclerosis (MS)Neuromyelitis Optica Spectrum Disease (NMOSD)Anti-Myelin Oligodendrocyte Glycoprotein-IgG Associated Disorders (MOGAD)+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 37
Very early researchNot Yet RecruitingNCT06933563
What this trial is testing

UCAR T-cell Therapy Targeting CD19/BCMA in Patients With r/r Myasthenia Gravis

Who this might be right for
Myasthenia Gravis
Zhejiang University 18
Post-approval studies (Phase 4)Not Yet RecruitingNCT06723548
What this trial is testing

Telitacicept and Low-dose Steroids in Refractory Myasthenia Gravis

Who this might be right for
Myasthenia GravisAutoimmune Diseases
First Affiliated Hospital of Wenzhou Medical University 30
Testing effectiveness (Phase 2)Study completedNCT00774462
What this trial is testing

Rituximab for the Treatment of Refractory Inflammatory Myopathies and Refractory Myasthenia Gravis

Who this might be right for
MyositisMyasthenia Gravis
Assistance Publique - Hôpitaux de Paris 30
Early research (Phase 1)Not Yet RecruitingNCT07304154
What this trial is testing

A Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases

Who this might be right for
Chronic Inflammatory Demyelinating PolyneuropathyMyasthenia GravisMultiple Sclerosis
Kite, A Gilead Company 52
Early research (Phase 1)Looking for participantsNCT06249438
What this trial is testing

C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy

Who this might be right for
Systemic Lupus Erythematosus (SLE)Immune-mediated Necrotizing Myopathy (IMNM)Neuromyelitis Optica Spectrum Disorders (NMOSD)+3 more
RenJi Hospital 30
Not applicableLooking for participantsNCT07470151
What this trial is testing

Clinical Study of EVM18001 in the Treatment of Refractory Autoimmune Diseases

Who this might be right for
System Lupus Erythematosus(SLE)SclerodermaMyasthenia Gravis (MG)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 12
Very early researchWithdrawnNCT06419166
What this trial is testing

An Exploratory Clinical Study of GC012F Injection for Refractory gMG

Who this might be right for
Refractory Generalized Myasthenia Gravis
Zhejiang University
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