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Results for “Refractory Myeloproliferative Neoplasm”

699 trials

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Showing 20 of 699 results

Testing effectiveness (Phase 2)Looking for participantsNCT03128034
What this trial is testing

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia+9 more
Fred Hutchinson Cancer Center 75
Testing effectiveness (Phase 2)Study completedNCT00053287
What this trial is testing

Fludarabine/Carboplatin/Topotecan w/Thalidomide for Relapsed/Refractory AML, CML and MDS

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Diseases
Case Comprehensive Cancer Center 42
Early research (Phase 1)Study completedNCT02352558
What this trial is testing

BBI608 in Adult Patients With Advanced, Refractory Hematologic Malignancies

Who this might be right for
Hematologic Malignancy
Sumitomo Pharma America, Inc. 15
Early research (Phase 1)Study completedNCT00038051
What this trial is testing

Evaluation of the Anti-CD-33 Immunotoxin Hum-195/rGel in Patients With Advanced Myeloid Malignancies

Who this might be right for
Acute Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyeloproliferative Disorders+1 more
M.D. Anderson Cancer Center 28
Testing effectiveness (Phase 2)Study completedNCT00245037
What this trial is testing

Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+4 more
OHSU Knight Cancer Institute 147
Not applicableEnded earlyNCT01077440
What this trial is testing

Presence of Donor-Derived DNA in Semen Samples From Cancer Survivors Who Underwent Donor Stem Cell Transplant

Who this might be right for
Cancer SurvivorChronic Myeloproliferative DisordersLeukemia+6 more
Vanderbilt University 24
Not applicableEnded earlyNCT00255684
What this trial is testing

Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing a Donor Umbilical Cord Blood Transplant for Hematologic Cancer

Who this might be right for
Chronic Myeloproliferative DisordersGraft Versus Host DiseaseLeukemia+4 more
University of Rochester 16
Large-scale testing (Phase 3)Ended earlyNCT00109538
What this trial is testing

Study of Lonafarnib Versus Placebo in Subjects With Either Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) (Study P02978AM3)(TERMINATED)

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicMyelodysplasia+1 more
Merck Sharp & Dohme LLC 47
Testing effectiveness (Phase 2)WithdrawnNCT02765997
What this trial is testing

StemRegenin-1 Expanded vs Unexpanded UCB for High Risk Heme Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphocytic LeukemiaChronic Myelogenous Leukemia+1 more
Masonic Cancer Center, University of Minnesota
Early research (Phase 1)Study completedNCT01684150
What this trial is testing

A Phase 1, Open-Label, Dose-Escalation & Expanded Cohort, Continuous IV Infusion, Multi-center Study of the Safety, Tolerability,PK & PD of EPZ-5676 in Treatment Relapsed/Refractory Patients With Leukemias Involving

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome+1 more
Epizyme, Inc. 51
Early research (Phase 1)Study completedNCT05665530
What this trial is testing

PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies

Who this might be right for
Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)Mantle Cell Lymphoma (MCL)+9 more
Prelude Therapeutics 86
Testing effectiveness (Phase 2)Active Not RecruitingNCT02935361
What this trial is testing

Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes
University of Southern California 33
Testing effectiveness (Phase 2)Study completedNCT01445080
What this trial is testing

Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

Who this might be right for
Blastic PhaseChildhood Acute Promyelocytic Leukemia With PML-RARAChildhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive+7 more
National Cancer Institute (NCI) 70
Testing effectiveness (Phase 2)Looking for participantsNCT03934372
What this trial is testing

Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors

Who this might be right for
Acute Myeloid LeukemiaAccelerated Phase Chronic Myeloid LeukemiaBlast Phase Chronic Myeloid Leukemia+6 more
Incyte Biosciences International Sàrl 70
Testing effectiveness (Phase 2)Study completedNCT00003406
What this trial is testing

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+4 more
Cancer Treatment Centers of America 30
Testing effectiveness (Phase 2)Ended earlyNCT00818649
What this trial is testing

Bortezomib and Vorinostat in Treating Patients With High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia

Who this might be right for
LeukemiaMyelodysplastic Syndrome
Masonic Cancer Center, University of Minnesota 16
Not applicableStudy completedNCT01499147
What this trial is testing

Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute LeukemiaChronic Myelogenous Leukemia+8 more
University of Illinois at Chicago 100
Early research (Phase 1)Study completedNCT01075425
What this trial is testing

Belinostat and Bortezomib in Treating Patients With Relapsed or Refractory Acute Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Lymphocytic LeukemiaAcute Myeloid LeukemiaMyelodysplastic Syndrome+1 more
Virginia Commonwealth University 41
Testing effectiveness (Phase 2)Study completedNCT01177371
What this trial is testing

High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Megakaryoblastic Leukemia (M7)+70 more
Case Comprehensive Cancer Center 13
Early research (Phase 1)Study completedNCT00042900
What this trial is testing

Pyroxamide in Treating Patients With Advanced Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+5 more
Memorial Sloan Kettering Cancer Center
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