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Results for “Refractory to Standard Therapies”

191 trials

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Showing 20 of 191 results

Large-scale testing (Phase 3)Study completedNCT00782145
What this trial is testing

A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+6 more
Tufts Medical Center 198
Early research (Phase 1)Study completedNCT00741234
What this trial is testing

A Phase I Dose Escalation Study of Oral SB939 Administered Alone or With Azacitidine

Who this might be right for
Solid TumorsHematologic MalignanciesMyelodysplastic Syndrome
S*BIO 85
Early research (Phase 1)Study completedNCT01430572
What this trial is testing

Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss Patients

Who this might be right for
Advanced CancersSolid Tumors
M.D. Anderson Cancer Center 62
Early research (Phase 1)Study completedNCT04676633
What this trial is testing

Safety, Tolerability, PK, Anti-Tumor Activity of STP705 in Subjects With Advanced/Metastatic or Surgically Unresectable Solid Tumors Who Are Refractory to Standard Therapy

Who this might be right for
Hepatocellular CarcinomaLiver MetastasesCholangiocarcinoma
Sirnaomics 5
Early research (Phase 1)Study completedNCT00607724
What this trial is testing

GDC-0449 in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Genentech, Inc. 68
Early research (Phase 1)Study completedNCT01209143
What this trial is testing

Pharmacokinetic Drug Interaction Study of the Hedgehog Pathway Inhibitor GDC-0449 in Combination With Rosiglitazone or Combined Oral Contraceptive in Patients With Locally Advanced or Metastatic Solid Tumors That Are Refractory to Standard Therapy or for Whom No Standard Therapy Exists

Who this might be right for
Solid Cancers
Genentech, Inc. 52
Testing effectiveness (Phase 2)Study completedNCT03637556
What this trial is testing

Pilot Study to Assess the Safety, PK and Iron Chelating Activity of DST-0509 (Deferasirox) in Thalassemia Patients Refractory to Chelation

Who this might be right for
Thalassemia Major
DisperSol Technologies, LLC 25
Large-scale testing (Phase 3)Looking for participantsNCT06413498
What this trial is testing

A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Kite, A Gilead Company 450
Large-scale testing (Phase 3)Study completedNCT02500043
What this trial is testing

Study of TAS-102 or Placebo Plus BSC in Patients With Metastatic Gastric Cancer

Who this might be right for
Refractory Metastatic Gastric Cancer
Taiho Oncology, Inc. 507
Early research (Phase 1)Study completedNCT04430842
What this trial is testing

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Who this might be right for
AstrocytomaBrain CancerBrain Metastases+20 more
Quadriga Biosciences, Inc. 15
Large-scale testing (Phase 3)Looking for participantsNCT06792253
What this trial is testing

Study Comparing BEBT-908 Combined With R to SOC for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Who this might be right for
Relapsed/Refractory Diffuse Large B-Cell Lymphoma
BeBetter Med Inc 416
Testing effectiveness (Phase 2)Study completedNCT00109707
What this trial is testing

Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies

Who this might be right for
Chronic Myelogenous LeukemiaAcute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)Hypereosinophilic Syndrome+1 more
Novartis Pharmaceuticals 507
Early research (Phase 1)Study completedNCT01014936
What this trial is testing

First-in-Man, Dose-escalation Trial of C-met Kinase Inhibitor MSC2156119J in Subjects With Advanced Solid Tumors

Who this might be right for
Patients With Solid Tumors, Either Refractory to Standard Therapy or for Which no Effective Standard Therapy is Available
EMD Serono 149
Testing effectiveness (Phase 2)Ended earlyNCT02089230
What this trial is testing

MEK Inhibitor 162 Relapsed and/or Refractory Acute Myeloid Leukemia (AML) and Poor Prognosis, Not Suitable for or Unwilling to Receive Standard Therapy

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 19
Early research (Phase 1)Looking for participantsNCT05272371
What this trial is testing

Immunotherapy With Dinutuximab Beta in Combination With Chemotherapy for the Treatment of Patients With Primary Neuroblastoma Refractory to Standard Therapy and With Relapsed or Progressive Disease

Who this might be right for
High-Risk Neuroblastoma
Jagiellonian University 20
Testing effectiveness (Phase 2)UnknownNCT02814864
What this trial is testing

Trial Evaluating the Efficacy of Systemic Mesenchymal Stromal Cell (MSC) Injections for the Treatment of Severe and Chronic Radiotherapy-induced Abdomino-pelvic Complications (Pelvic Radiation Disease, PRD) Refractory to Standard Therapy

Who this might be right for
Pelvic Radiation TherapyRadiation-induced Hemorrhagic Cystitis
Assistance Publique - Hôpitaux de Paris 12
Early research (Phase 1)Looking for participantsNCT06883539
What this trial is testing

A Phase I Study of LXP1788 Injection with Advanced Solid Tumors.

Who this might be right for
Solid Tumor Malignancies, CancerSolid CancersSolid Tumor Cancer+6 more
LaunXP Biomedical Co., Ltd. 24
Testing effectiveness (Phase 2)UnknownNCT06039202
What this trial is testing

Phase 2 Study of CA102N Combined With TAS-102 Compared to Bevacizumab Combined With TAS-102 in Subjects With Relapsed and/or Refractory Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Holy Stone Healthcare Co., Ltd 100
Large-scale testing (Phase 3)Study completedNCT03391466
What this trial is testing

Study of Effectiveness of Axicabtagene Ciloleucel Compared to Standard of Care Therapy in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma

Who this might be right for
Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Kite, A Gilead Company 359
Early research (Phase 1)Not Yet RecruitingNCT07341828
What this trial is testing

C-CAR168 in the Treatment of Central Nervous System Autoimmune Diseases Refractory to Standard Therapy

Who this might be right for
Multiple Sclerosis (MS)Neuromyelitis Optica Spectrum Disorders (NMOSD)Autoimmune Encephalitis+1 more
Huashan Hospital 15
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