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Results for “Refractory to Standard Therapies”

192 trials

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Showing 20 of 192 results

Large-scale testing (Phase 3)Study completedNCT00666211
What this trial is testing

Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
Vanderbilt-Ingram Cancer Center 98
Not applicableLooking for participantsNCT06455475
What this trial is testing

Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone

Who this might be right for
Diabetic Foot Ulcer
Capsicure, LLC 150
Testing effectiveness (Phase 2)UnknownNCT01653067
What this trial is testing

STORM: Temsirolimus, Rituximab and DHAP for Relapsed and Refractory Diffuse Large B-cell Lymphoma

Who this might be right for
Diffuse Large B-Cell Lymphoma
Mathias Witzens-Harig 88
Early research (Phase 1)Study completedNCT00728936
What this trial is testing

Placebo-controlled, Dose-escalation Study of the Safety of IMO-2125 (Immunomodulatory Oligonucleotide) in Hepatitis C-infected Patients

Who this might be right for
Hepatitis C
Idera Pharmaceuticals, Inc. 58
Not applicableNo Longer AvailableNCT00210665
What this trial is testing

Provide Access to Trabectedin in Participants With Locally Advanced or Metastatic Soft Tissue Sarcoma Who Have Persistent or Recurrent Disease and Who Are Not Expected to Benefit From Currently Available Standard of Care Treatment

Who this might be right for
Sarcoma
Janssen Research & Development, LLC
Large-scale testing (Phase 3)Looking for participantsNCT06589804
What this trial is testing

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

Who this might be right for
Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell CarcinomaMetastatic Laryngeal Squamous Cell Carcinoma+18 more
National Cancer Institute (NCI) 158
Early research (Phase 1)Study completedNCT01209143
What this trial is testing

Pharmacokinetic Drug Interaction Study of the Hedgehog Pathway Inhibitor GDC-0449 in Combination With Rosiglitazone or Combined Oral Contraceptive in Patients With Locally Advanced or Metastatic Solid Tumors That Are Refractory to Standard Therapy or for Whom No Standard Therapy Exists

Who this might be right for
Solid Cancers
Genentech, Inc. 52
Testing effectiveness (Phase 2)Study completedNCT02342665
What this trial is testing

Japanese Phase Ib/II Copanlisib in Relapsed, Indolent B-cell NHL

Who this might be right for
Lymphoma Non-Hodgkin
Bayer 25
Testing effectiveness (Phase 2)Study completedNCT00005941
What this trial is testing

Peripheral Stem Cell Transplant, White Blood Cell Infusions, Chemotherapy, and Radiation Therapy in Treating Patients With Recurrent Metastatic Cervical or Vaginal Cancer

Who this might be right for
Cervical CancerVaginal Cancer
Fred Hutchinson Cancer Center
Early research (Phase 1)Study completedNCT03985072
What this trial is testing

Study With Andes-1537 in Patients With Specific Types of Advanced Solid Tumor

Who this might be right for
Tumor, SolidGall Bladder CancerCervical Cancer+3 more
Andes Biotechnologies 67
Testing effectiveness (Phase 2)Study completedNCT01164995
What this trial is testing

Study With Wee-1 Inhibitor AZD1775 (MK-1775) and Carboplatin to Treat p53 Mutated Refractory and Resistant Ovarian Cancer

Who this might be right for
Epithelial Ovarian Cancer
The Netherlands Cancer Institute 24
Testing effectiveness (Phase 2)Ended earlyNCT02401542
What this trial is testing

Dose Escalation, Expansion Study of Vofatamab (B-701) in Treatment of Locally Advanced or Metastatic Urothelial Cell Carcinoma

Who this might be right for
Locally Advanced or Metastatic Urothelial Cell CarcinomaUrinary Bladder DiseaseUrological Diseases
Rainier Therapeutics 71
Testing effectiveness (Phase 2)Study completedNCT00679354
What this trial is testing

Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy

Who this might be right for
Childhood High-grade Cerebellar AstrocytomaChildhood High-grade Cerebral AstrocytomaRecurrent Childhood Anaplastic Astrocytoma+7 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Looking for participantsNCT06873659
What this trial is testing

SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors

Who this might be right for
Solid TumorGastric CancerLiver Cancer
Qurgen Inc. 96
Testing effectiveness (Phase 2)UnknownNCT00043199
What this trial is testing

A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Colorectal Cancer Resistant to Standard Therapies

Who this might be right for
Colorectal Neoplasms
Aronex Pharmaceuticals 40
Early research (Phase 1)Study completedNCT01397799
What this trial is testing

Evaluation of KX2-391 in Elderly Subjects With Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myelogenous Leukemia
Kinex Pharmaceuticals Inc. 24
Early research (Phase 1)Study completedNCT00339144
What this trial is testing

Study of Dasatinib (BMS-354825) in Patients With Solid Tumors

Who this might be right for
Tumors
Bristol-Myers Squibb 16
Large-scale testing (Phase 3)Ended earlyNCT03221842
What this trial is testing

Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients

Who this might be right for
Antibody-mediated Rejection
CSL Behring 63
Early research (Phase 1)Looking for participantsNCT05137054
What this trial is testing

Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Patients With Multiple Myeloma That is Resistant to Current Standard of Care Treatments

Who this might be right for
Multiple Myeloma
Regeneron Pharmaceuticals 317
Testing effectiveness (Phase 2)Looking for participantsNCT07309770
What this trial is testing

Trastuzumab Rezetecan in Advanced Solid Tumors Refractory to Standard Therapies

Who this might be right for
Urachal CancerAdvanced Solid Tumor CancerAntibody-drug Conjugates
Sheng Zhang 90
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