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Results for “Relapsed/Refractory Hematological Malignancies”

476 trials

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Showing 20 of 476 results

Testing effectiveness (Phase 2)Study completedNCT00245037
What this trial is testing

Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+4 more
OHSU Knight Cancer Institute 147
Not applicableEnded earlyNCT00255684
What this trial is testing

Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing a Donor Umbilical Cord Blood Transplant for Hematologic Cancer

Who this might be right for
Chronic Myeloproliferative DisordersGraft Versus Host DiseaseLeukemia+4 more
University of Rochester 16
Early research (Phase 1)Not Yet RecruitingNCT07113496
What this trial is testing

RN1201injection for Relapsed/Refractory CD19+/BCMA+ Hematologic Malignancies

Who this might be right for
Relapsed or Refractory B-cell Hematologic MalignanciesB-cell Acute Lymphoblastic Leukemia (B-ALL)Multiple Myeloma (MM)+3 more
The First Affiliated Hospital with Nanjing Medical University 27
Early research (Phase 1)Study completedNCT01684150
What this trial is testing

A Phase 1, Open-Label, Dose-Escalation & Expanded Cohort, Continuous IV Infusion, Multi-center Study of the Safety, Tolerability,PK & PD of EPZ-5676 in Treatment Relapsed/Refractory Patients With Leukemias Involving

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome+1 more
Epizyme, Inc. 51
Early research (Phase 1)Study completedNCT05665530
What this trial is testing

PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies

Who this might be right for
Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)Mantle Cell Lymphoma (MCL)+9 more
Prelude Therapeutics 86
Early research (Phase 1)Looking for participantsNCT05892718
What this trial is testing

A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors

Who this might be right for
Advanced Solid TumorRefractory Non-Hodgkin Lymphoma
FBD Biologics Limited 80
Very early researchLooking for participantsNCT04532203
What this trial is testing

CAR-T Cells Therapy for Patients With Relapsed and/or Refractory Central Nervous System Hematological Malignancies

Who this might be right for
Acute Lymphoblastic LeukemiaNon-Hodgkin's Lymphoma
Zhejiang University 72
Not applicableLooking for participantsNCT05237986
What this trial is testing

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

Who this might be right for
LymphomaLeukemia
National Cancer Institute (NCI) 60
Very early researchLooking for participantsNCT04603872
What this trial is testing

CAR-T Cells Combined With Dasatinib for Patients With Relapsed and/or Refractory B-cell Hematological Malignancies

Who this might be right for
Multiple Myeloma in RelapseMultiple Myeloma, RefractoryAcute Lymphoblastic Leukemia, in Relapse+3 more
Zhejiang University 120
Testing effectiveness (Phase 2)Study completedNCT00721734
What this trial is testing

Study of the Safety and Pharmacokinetics of Carfilzomib in Patients With Relapsed and Refractory Multiple Myeloma and Varying Degrees of Renal Function

Who this might be right for
Multiple MyelomaRenal Insufficiency
Amgen 50
Testing effectiveness (Phase 2)Study completedNCT00003406
What this trial is testing

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+4 more
Cancer Treatment Centers of America 30
Very early researchUnknownNCT04767308
What this trial is testing

Safety and Efficacy of CT125A Cells for Treatment of Relapsed/Refractory CD5+ Hematopoietic Malignancies

Who this might be right for
CD5+ Relapsed/Refractory Hematopoietic MalignanciesChronic Lymphocytic Leukemia (CLL)Mantle Cell Lymphoma (MCL)+3 more
Huazhong University of Science and Technology 18
Not applicableStudy completedNCT01499147
What this trial is testing

Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute LeukemiaChronic Myelogenous Leukemia+8 more
University of Illinois at Chicago 100
Early research (Phase 1)Study completedNCT00042900
What this trial is testing

Pyroxamide in Treating Patients With Advanced Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+5 more
Memorial Sloan Kettering Cancer Center
Large-scale testing (Phase 3)UnknownNCT06238336
What this trial is testing

Clinical Study of CAR-T Technology for the Treatment of Relapsed Refractory Malignant Haematological Tumours

Who this might be right for
Hematological Malignancy
Shanxi Bethune Hospital 30
Early research (Phase 1)UnknownNCT03757000
What this trial is testing

A Phase I Study of YY-20394 in Patients With B Cell Hematologic Malignancies

Who this might be right for
B-cell Lymphoma RecurrentB-cell Chronic Lymphocytic Leukemia
Shanghai YingLi Pharmaceutical Co. Ltd. 42
Early research (Phase 1)Active Not RecruitingNCT04603001
What this trial is testing

Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)Chronic Myelomonocytic Leukemia (CMML)+1 more
Eli Lilly and Company 260
Testing effectiveness (Phase 2)Study completedNCT00014469
What this trial is testing

Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Advanced Hematologic Cancer

Who this might be right for
Graft Versus Host DiseaseLeukemiaMyelodysplastic Syndromes+1 more
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Looking for participantsNCT06690827
What this trial is testing

Clinical Trial of CD123-targeted CAR-NK Therapy for Relapse/refractory AML or BPDCN

Who this might be right for
AML (Acute Myeloid Leukemia)BPDCN (blastic Plasmacytoid Dendritic Cell Neoplasm)
Chongqing Precision Biotech Co., Ltd 30
Testing effectiveness (Phase 2)Looking for participantsNCT03670966
What this trial is testing

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia in Remission+9 more
Fred Hutchinson Cancer Center 30
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